Paper · 21620132

PK-M2 Makes Cells Sweeter on HIF1.

Tennant DA. Cell, 2011. Cited by 21 papers, by iCite.

11 sourcespapers-2026-11-12-0.1.0

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ConductScience Library. PK-M2 Makes Cells Sweeter on HIF1. Papers, record 21620132. Release papers-2026-11-12-0.1.0, 12 Nov 2026. https://conductscience.org/library/papers/21620132

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Paper

PubMed's record of the paper, with iCite's citation figures. No abstract is shown.

Title: PK-M2 Makes Cells Sweeter on HIF1.; PubMed
Journal: Cell; PubMed
Year: 2011; PubMed
Publication types: Comment, Journal Article; PubMed
PubMed: https://pubmed.ncbi.nlm.nih.gov/21620132/; PubMed
DOI: https://doi.org/10.1016/j.cell.2011.05.009; PubMed
The journal: https://conductscience.org/library/journal-index/0413066; PubMed
Citations, by iCite: 21; iCite
Relative citation ratio, by iCite: 0.46; iCite
Revised in PubMed: 2011-05-30; PubMed

Authors1

The authors in the order PubMed's record lists them, with the ORCID iDs it states.

Order	Author	Forename	Kind	ORCID iD
1	Tennant DA	Daniel A

Source PubMed

Topics0

NLM's MeSH indexing of the paper, its major topics first.

None in this release.

Grants0

Each grant PubMed's record writes, matched to the NIH project NIH's grant and paper links name for this paper, and each of those links the record does not write.

None in this release.

Trials0

The trials whose ClinicalTrials.gov record lists the paper, and the trial numbers the paper's PubMed record names.

None in this release.

Comments and corrections1

PubMed's comments and corrections, NLM's own indexing: retractions first, then expressions of concern, errata and updates, and comments last.

Kind	PMID	Title	In Papers
Comment on	21,620,138	Pyruvate kinase M2 is a PHD3-stimulated coactivator for hypoxia-inducible factor 1.	https://conductscience.org/library/papers/21620138

Source PubMed

References0

The papers the reference list in PubMed's record names, those in our copy of PubMed, in the list's order.

None in this release.

Cited by14

The papers in our copy of PubMed whose reference list names this one, newest first. iCite, which reads more sources, counts 21 citations.

PMID	Title	Journal	Year	In Papers	Source
41,372,616	Succinate-driven PKM2 succinylation and dimerization accelerates age-associated cardiac fibrosis.	Commun Biol	2025	https://conductscience.org/library/papers/41372616	PubMed
41,347,875	Conformational Dynamics of PKM2 Regulate Hypoxia-Induced Pathological Retinal Angiogenesis.	Invest Ophthalmol Vis Sci	2025	https://conductscience.org/library/papers/41347875	PubMed
38,282,712	Angiotensin-(1-7) Modulates the Warburg Effect to Alleviate Inflammation in LPS-Induced Macrophages and Septic Mice.	J Inflamm Res	2024	https://conductscience.org/library/papers/38282712	PubMed
35,429,904	AKR1C1 promotes non-small cell lung cancer proliferation via crosstalk between HIF-1α and metabolic reprogramming.	Transl Oncol	2022	https://conductscience.org/library/papers/35429904	PubMed
34,471,821	Potassium and Sodium Channels and the Warburg Effect: Biophysical Regulation of Cancer Metabolism.	Bioelectricity	2019	https://conductscience.org/library/papers/34471821	PubMed
33,953,708	Glycolytic Metabolism Is Critical for the Innate Antibacterial Defense in Acute Streptococcus pneumoniae Otitis Media.	Front Immunol	2021	https://conductscience.org/library/papers/33953708	PubMed
32,391,119	Lactate induces PD-L1 in HRASG12V-positive oropharyngeal squamous cell carcinoma.	Oncotarget	2020	https://conductscience.org/library/papers/32391119	PubMed
30,255,690	Dysregulation of Glucose Metabolism by Oncogenes and Tumor Suppressors in Cancer Cells	Asian Pac J Cancer Prev	2018	https://conductscience.org/library/papers/30255690	PubMed
29,204,551	mTOR, metabolism, and the immune response in HPV-positive head and neck squamous cell cancer.	World J Otorhinolaryngol Head Neck Surg	2016	https://conductscience.org/library/papers/29204551	PubMed
28,281,307	Integrated expression analysis identifies transcription networks in mouse and human gastric neoplasia.	Genes Chromosomes Cancer	2017	https://conductscience.org/library/papers/28281307	PubMed

1 to 10 of 14

See all 14 cited by

Genes2

The genes the Gene search release ties to the paper: Swiss-Prot's references first, then PubTator's text mining.

Gene	NCBI Gene ID	Linked by	In Genes	Source
HIF1A	3,091	PubTator's text mining	https://conductscience.org/library/genes/3091	NCBI Gene
PKM	5,315	PubTator's text mining	https://conductscience.org/library/genes/5315	NCBI Gene

Drugs0

The drugs whose trials, in the Pipelines release, list the paper.

None in this release.

Data0

The data bank entries PubMed's record names. Trial numbers are under Trials.

None in this release.

Data dates

The date of each source this release read.

PubMed: 2026-11-06; PubMed
iCite: 2026-11-05; iCite
PMC's ID file: 2026-11-05; PMC's ID file
NIH RePORTER's grant and paper links: 2026-11-01; NIH RePORTER's grant and paper links
Trials: 2026-11-12
Gene search: 2026-11-11
Pipelines: 2026-09-18

Sources 11

ChEMBL, through Open TargetsCC BY-SA 3.0
ClinicalTrials.govNo license stated
HGNCCC0
iCiteCC BY 4.0
NCBI GenePublic domain (US government)
NIH RePORTER's grant and paper linksPublic domain
Open TargetsCC0 1.0
PMC's ID filePublic domain (US government)
PubMedNLM's terms
PubTator 3Public domain
UniProtCC BY 4.0

Each source's terms

ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
ClinicalTrials.govnone stated
HGNCCC0: https://www.genenames.org/about/license/
iCiteCC BY 4.0
NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
NIH RePORTER's grant and paper linksPublic domain (NIH RePORTER)
Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
PMC's ID fileNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
PubMedNLM's terms
PubTator 3Public domain
UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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