Paper · 218668

Hyperpolarizing 'alpha 2'-adrenoceptors in rat sympathetic ganglia.

Brown DA and 1 other. Br J Pharmacol, 1979. Cited by 151 papers, by iCite.

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ConductScience Library. Hyperpolarizing 'alpha 2'-adrenoceptors in rat sympathetic ganglia. Papers, record 218668. Release papers-2026-11-12-0.1.0, 12 Nov 2026. https://conductscience.org/library/papers/218668

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Paper

PubMed's record of the paper, with iCite's citation figures. No abstract is shown.

Title: Hyperpolarizing 'alpha 2'-adrenoceptors in rat sympathetic ganglia.; PubMed
Journal: Br J Pharmacol; PubMed
Year: 1979; PubMed
Publication types: Journal Article; PubMed
PubMed: https://pubmed.ncbi.nlm.nih.gov/218668/; PubMed
DOI: https://doi.org/10.1111/j.1476-5381.1979.tb07848.x; PubMed
PMC: https://pmc.ncbi.nlm.nih.gov/articles/PMC1668647/; PubMed
The journal: https://conductscience.org/library/journal-index/7502536; PubMed
Citations, by iCite: 151; iCite
Relative citation ratio, by iCite: 6.83; iCite
Revised in PubMed: 2019-05-09; PubMed

Authors2

The authors in the order PubMed's record lists them, with the ORCID iDs it states.

Order	Author	Forename	Kind	ORCID iD
1	Brown DA	D A
2	Caulfield MP	M P

Source PubMed

Topics16

NLM's MeSH indexing of the paper, its major topics first.

MeSH term	Major
Ganglia, Autonomic	Major topic
Receptors, Adrenergic	Major topic
Receptors, Adrenergic, alpha	Major topic
Animals
Catecholamines
Clonidine
In Vitro Techniques
Isoproterenol
Male
Norepinephrine
Oxymetazoline
Phentolamine
Propranolol
Rats
Receptors, Dopamine
Time Factors

Source PubMed

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Trials0

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Comments and corrections0

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References45

The papers the reference list in PubMed's record names, those in our copy of PubMed, in the list's order.

Order	PMID	Title	Journal	Year	In Papers	Source
1	14,343,876	AMIDEPHRINE--I: PHARMACOLOGIC CHARACTERIZATION OF A SYMPATHOMIMETIC ALKYLSULFONAMIDOPHENETHANOLAMINE.	Int J Neuropharmacol	1965	https://conductscience.org/library/papers/14343876	PubMed
2	13,651,579	Some quantitative uses of drug antagonists.	Br J Pharmacol Chemother	1959	https://conductscience.org/library/papers/13651579	PubMed
3	11,342	On the receptors which mediate the hyperpolarization of salivary gland cells of Nauphoeta cinerea Olivier.	J Physiol	1976	https://conductscience.org/library/papers/11342	PubMed
4	14,389	Regulation of noradrenaline release by presynaptic receptor systems.	Rev Physiol Biochem Pharmacol	1977	https://conductscience.org/library/papers/14389	PubMed
5	20,542	A functional basis for classification of alpha-adrenergic receptors.	Life Sci	1977	https://conductscience.org/library/papers/20542	PubMed
6	14,838	Pharmacological characterisation of the presynaptic alpha-adrenoceptor in the rat vas deferens.	Eur J Pharmacol	1977	https://conductscience.org/library/papers/14838	PubMed
7	14,760	Prazosin, a selective antagonist of post-synaptic alpha-adrenoceptors [proceedings].	Br J Pharmacol	1977	https://conductscience.org/library/papers/14760	PubMed
8	18,248	Selectivity of blocking agents for pre-and postsynaptic alpha-adrenoceptors.	Br J Pharmacol	1977	https://conductscience.org/library/papers/18248	PubMed
9	211,445	Responses of the rat superior cervical ganglion in vitro to isoprenaline and bethanechol.	Naunyn Schmiedebergs Arch Pharmacol	1978	https://conductscience.org/library/papers/211445	PubMed
10	202,881	Effect of butyrophenones on the sympathetic nerves of the isolated rabbit heart and on the postsynaptic alpha-adrenoceptors of the isolated rabbit aorta.	Naunyn Schmiedebergs Arch Pharmacol	1977	https://conductscience.org/library/papers/202881	PubMed

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Cited by39

The papers in our copy of PubMed whose reference list names this one, newest first. iCite, which reads more sources, counts 151 citations.

PMID	Title	Journal	Year	In Papers	Source
23,983,779	Mechanisms of electroacupuncture-induced analgesia on neuropathic pain in animal model.	Evid Based Complement Alternat Med	2013	https://conductscience.org/library/papers/23983779	PubMed
11,724,754	Effect of chronic clonidine treatment on transmitter release from sympathetic varicosities of the guinea-pig vas deferens.	Br J Pharmacol	2001	https://conductscience.org/library/papers/11724754	PubMed
10,454,061	One hundred years of adrenaline: the discovery of autoreceptors.	Clin Auton Res	1999	https://conductscience.org/library/papers/10454061	PubMed
8,242,261	Characterization of the adenosine receptors of the rat superior cervical ganglion.	Br J Pharmacol	1993	https://conductscience.org/library/papers/8242261	PubMed
7,110,381	Apomorphine contracts and relaxes circular smooth muscle of guinea-pig stomach via action on adrenoceptor mechanisms.	Naunyn Schmiedebergs Arch Pharmacol	1982	https://conductscience.org/library/papers/7110381	PubMed
6,323,699	Examination of the role of the electrogenic sodium pump in the adrenaline-induced hyperpolarization of amphibian neurones.	J Physiol	1984	https://conductscience.org/library/papers/6323699	PubMed
6,317,111	Cyclic adenosine 3',5'-monophosphate and beta-effects in rat isolated superior cervical ganglia.	Br J Pharmacol	1983	https://conductscience.org/library/papers/6317111	PubMed
6,274,464	Clonidine activates membrane potassium conductance in myenteric neurones.	Br J Pharmacol	1981	https://conductscience.org/library/papers/6274464	PubMed
6,272,131	Studies on the role of Na+, K+ and Cl- ion permeabilities in K+-induced release of 3H-noradrenaline from rat brain slices and synaptosomes and in its presynaptic alpha-adrenergic modulation.	Naunyn Schmiedebergs Arch Pharmacol	1981	https://conductscience.org/library/papers/6272131	PubMed
6,267,264	Site(s) and ionic basis of alpha-autoinhibition and facilitation of "3H'noradrenaline secretion in guinea-pig vas deferens.	J Physiol	1981	https://conductscience.org/library/papers/6267264	PubMed

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Data0

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Data dates

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PubMed: 2026-11-06; PubMed
iCite: 2026-11-05; iCite
PMC's ID file: 2026-11-05; PMC's ID file
NIH RePORTER's grant and paper links: 2026-11-01; NIH RePORTER's grant and paper links
Trials: 2026-11-12
Gene search: 2026-11-11
Pipelines: 2026-09-18

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ClinicalTrials.govNo license stated
HGNCCC0
iCiteCC BY 4.0
NCBI GenePublic domain (US government)
NIH RePORTER's grant and paper linksPublic domain
Open TargetsCC0 1.0
PMC's ID filePublic domain (US government)
PubMedNLM's terms
PubTator 3Public domain
UniProtCC BY 4.0

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ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
ClinicalTrials.govnone stated
HGNCCC0: https://www.genenames.org/about/license/
iCiteCC BY 4.0
NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
NIH RePORTER's grant and paper linksPublic domain (NIH RePORTER)
Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
PMC's ID fileNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
PubMedNLM's terms
PubTator 3Public domain
UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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