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Paper · 2581996

A unique control mechanism in the regulation of insulin secretion. Secretagogue-induced somatostatin receptor recruitment.

Draznin B and 2 others. J Clin Invest, 1985. Cited by 17 papers, by iCite.

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ConductScience Library. A unique control mechanism in the regulation of insulin secretion. Secretagogue-induced somatostatin receptor recruitment. Papers, record 2581996. Release papers-2026-11-12-0.1.0, 12 Nov 2026. https://conductscience.org/library/papers/2581996

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Paper

PubMed's record of the paper, with iCite's citation figures. No abstract is shown.

Title
A unique control mechanism in the regulation of insulin secretion. Secretagogue-induced somatostatin receptor recruitment.
PubMed
Journal
J Clin Invest
PubMed
Year
1985
PubMed
Publication types
Journal Article, Research Support, Non-U.S. Gov't, Research Support, U.S. Gov't, Non-P.H.S., Research Support, U.S. Gov't, P.H.S.
PubMed
Citations, by iCite
17
iCite
Relative citation ratio, by iCite
0.67
iCite
Revised in PubMed
2018-12-17
PubMed

Authors3

The authors in the order PubMed's record lists them, with the ORCID iDs it states.

OrderAuthorForenameKindORCID iD
1Draznin BB
2Leitner JWJ W
3Sussman KEK E

Source PubMed

Topics14

NLM's MeSH indexing of the paper, its major topics first.

MeSH termMajor
InsulinMajor topic
Receptors, Cell SurfaceMajor topic
SomatostatinMajor topic
1-Methyl-3-isobutylxanthine
Animals
Binding, Competitive
Glucose
In Vitro Techniques
Insulin Secretion
Islets of Langerhans
Male
Rats
Rats, Inbred Strains
Receptors, Somatostatin

Source PubMed

Grants1

Each grant PubMed's record writes, matched to the NIH project NIH's grant and paper links name for this paper, and each of those links the record does not write.

Grant, as the record writes itAgencyCountryNIH projectStated by
AM 32006NIADDK NIH HHSUnited StatesR01AM032006PubMed and NIH

Source NIH RePORTER

Trials0

The trials whose ClinicalTrials.gov record lists the paper, and the trial numbers the paper's PubMed record names.

None in this release.

Comments and corrections0

PubMed's comments and corrections, NLM's own indexing: retractions first, then expressions of concern, errata and updates, and comments last.

None in this release.

References18

The papers the reference list in PubMed's record names, those in our copy of PubMed, in the list's order.

OrderPMIDTitleJournalYearIn PapersSource
15,333,500Method for the isolation of intact islets of Langerhans from the rat pancreas.Diabetes1967https://conductscience.org/library/papers/5333500PubMed
2400,768Mechanisms of impaired acute insulin release in adult onset diabetes: studies with isoproterenol and secretin.J Clin Endocrinol Metab1978https://conductscience.org/library/papers/400768PubMed
3447,800Potentiation of insulin secretory responses by plasma glucose levels in man: evidence that hyperglycemia in diabetes compensates for imparied glucose potentiation.J Clin Endocrinol Metab1979https://conductscience.org/library/papers/447800PubMed
47,000,591Hypothesis: single and chain release of insulin secretory granules is related to anionic transport at exocytotic sites.Diabetes1980https://conductscience.org/library/papers/7000591PubMed
56,107,815The relationship between somatostatin binding and cyclic AMP-stimulated protein kinase inhibition.Metabolism1980https://conductscience.org/library/papers/6107815PubMed
66,108,333Role of insulin secretagogues in the regulation of somatostatin binding by isolated rat islets.J Clin Invest1980https://conductscience.org/library/papers/6108333PubMed
77,009,282The milieu interieur and the islets of Langerhans.Diabetologia1981https://conductscience.org/library/papers/7009282PubMed
86,115,787Evidence for the hormonal status of somatostatin in man.Diabetes1981https://conductscience.org/library/papers/6115787PubMed
96,123,431Role of the secretion vesicle in the transport of receptors: modulation of somatostatin binding to pancreatic islets.Endocrinology1982https://conductscience.org/library/papers/6123431PubMed
106,126,003Quantitative electron microscopic autoradiography of insulin, glucagon, and somatostatin binding sites on islets.Science1982https://conductscience.org/library/papers/6126003PubMed

1 to 10 of 18

See all 18 references

Cited by2

The papers in our copy of PubMed whose reference list names this one, newest first. iCite, which reads more sources, counts 17 citations.

PMIDTitleJournalYearIn PapersSource
7,905,262Stimulation by prostaglandin E2 of a high-affinity GTPase in the secretory granules of normal rat and human pancreatic islets.Biochem J1994https://conductscience.org/library/papers/7905262PubMed
2,895,122Exocytosis in normal anterior pituitary cells. Quantitative correlation between growth hormone release and the morphological features of exocytosis.J Clin Invest1988https://conductscience.org/library/papers/2895122PubMed

Genes2

The genes the Gene search release ties to the paper: Swiss-Prot's references first, then PubTator's text mining.

GeneNCBI Gene IDLinked byIn GenesSource
INS3,630PubTator's text mininghttps://conductscience.org/library/genes/3630NCBI Gene
SST6,750PubTator's text mininghttps://conductscience.org/library/genes/6750NCBI Gene

Drugs0

The drugs whose trials, in the Pipelines release, list the paper.

None in this release.

Data0

The data bank entries PubMed's record names. Trial numbers are under Trials.

None in this release.

Data dates

The date of each source this release read.

PubMed
2026-11-06
PubMed
iCite
2026-11-05
iCite
PMC's ID file
2026-11-05
PMC's ID file
NIH RePORTER's grant and paper links
2026-11-01
NIH RePORTER's grant and paper links
Trials
2026-11-12
Gene search
2026-11-11
Pipelines
2026-09-18

Sources 11

  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • HGNCCC0
  • iCiteCC BY 4.0
  • NCBI GenePublic domain (US government)
  • NIH RePORTER's grant and paper linksPublic domain
  • Open TargetsCC0 1.0
  • PMC's ID filePublic domain (US government)
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • HGNCCC0: https://www.genenames.org/about/license/
  • iCiteCC BY 4.0
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH RePORTER's grant and paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PMC's ID fileNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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