Paper · 400768

Mechanisms of impaired acute insulin release in adult onset diabetes: studies with isoproterenol and secretin.

Halter JB and 1 other. J Clin Endocrinol Metab, 1978. Cited by 42 papers, by iCite.

11 sourcespapers-2026-11-12-0.1.0

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ConductScience Library. Mechanisms of impaired acute insulin release in adult onset diabetes: studies with isoproterenol and secretin. Papers, record 400768. Release papers-2026-11-12-0.1.0, 12 Nov 2026. https://conductscience.org/library/papers/400768

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Paper

PubMed's record of the paper, with iCite's citation figures. No abstract is shown.

Title: Mechanisms of impaired acute insulin release in adult onset diabetes: studies with isoproterenol and secretin.; PubMed
Journal: J Clin Endocrinol Metab; PubMed
Year: 1978; PubMed
Publication types: Journal Article, Research Support, U.S. Gov't, Non-P.H.S., Research Support, U.S. Gov't, P.H.S.; PubMed
PubMed: https://pubmed.ncbi.nlm.nih.gov/400768/; PubMed
DOI: https://doi.org/10.1210/jcem-46-6-952; PubMed
The journal: https://conductscience.org/library/journal-index/0375362; PubMed
Citations, by iCite: 42; iCite
Relative citation ratio, by iCite: 1.29; iCite
Revised in PubMed: 2018-12-17; PubMed

Authors2

The authors in the order PubMed's record lists them, with the ORCID iDs it states.

Order	Author	Forename	Kind	ORCID iD
1	Halter JB	J B
2	Porte D Jr	D

Source PubMed

Topics12

NLM's MeSH indexing of the paper, its major topics first.

MeSH term	Major
Diabetes Mellitus, Type 2	Major topic
Insulin	Major topic
Isoproterenol	Major topic
Secretin	Major topic
Aged
Blood Glucose
Glucose Tolerance Test
Humans
Insulin Secretion
Male
Middle Aged
Reference Values

Source PubMed

Grants3

Each grant PubMed's record writes, matched to the NIH project NIH's grant and paper links name for this paper, and each of those links the record does not write.

Grant, as the record writes it	Agency	Country	Stated by
AM-05498	NIADDK NIH HHS	United States	PubMed
AM-12829	NIADDK NIH HHS	United States	PubMed
AM-20754	NIADDK NIH HHS	United States	PubMed

Source PubMed

Trials0

The trials whose ClinicalTrials.gov record lists the paper, and the trial numbers the paper's PubMed record names.

None in this release.

Comments and corrections0

PubMed's comments and corrections, NLM's own indexing: retractions first, then expressions of concern, errata and updates, and comments last.

None in this release.

References0

The papers the reference list in PubMed's record names, those in our copy of PubMed, in the list's order.

None in this release.

Cited by6

The papers in our copy of PubMed whose reference list names this one, newest first. iCite, which reads more sources, counts 42 citations.

PMID	Title	Journal	Year	In Papers	Source
41,575,482	Gut Peptide Alterations in Type 2 Diabetes and Obesity: A Narrative Review.	Curr Obes Rep	2026	https://conductscience.org/library/papers/41575482	PubMed
38,118,001	Daniel Porte Jr., 13 August 1931-13 May 2023.	Diabetes	2024	https://conductscience.org/library/papers/38118001	PubMed
34,671,320	Pleiotropic Effects of Secretin: A Potential Drug Candidate in the Treatment of Obesity?	Front Endocrinol (Lausanne)	2021	https://conductscience.org/library/papers/34671320	PubMed
12,637,977	The relative contributions of insulin resistance and beta-cell dysfunction to the pathophysiology of Type 2 diabetes.	Diabetologia	2003	https://conductscience.org/library/papers/12637977	PubMed
3,907,235	Glycemic control with an artificial pancreas improves insulin responses to both oral and glucose in nonobese noninsulin-dependent diabetic subjects.	Acta Diabetol Lat	1985	https://conductscience.org/library/papers/3907235	PubMed
2,581,996	A unique control mechanism in the regulation of insulin secretion. Secretagogue-induced somatostatin receptor recruitment.	J Clin Invest	1985	https://conductscience.org/library/papers/2581996	PubMed

Genes2

The genes the Gene search release ties to the paper: Swiss-Prot's references first, then PubTator's text mining.

Gene	NCBI Gene ID	Linked by	In Genes	Source
INS	3,630	PubTator's text mining	https://conductscience.org/library/genes/3630	NCBI Gene
SCT	6,343	PubTator's text mining	https://conductscience.org/library/genes/6343	NCBI Gene

Drugs0

The drugs whose trials, in the Pipelines release, list the paper.

None in this release.

Data0

The data bank entries PubMed's record names. Trial numbers are under Trials.

None in this release.

Data dates

The date of each source this release read.

PubMed: 2026-11-06; PubMed
iCite: 2026-11-05; iCite
PMC's ID file: 2026-11-05; PMC's ID file
NIH RePORTER's grant and paper links: 2026-11-01; NIH RePORTER's grant and paper links
Trials: 2026-11-12
Gene search: 2026-11-11
Pipelines: 2026-09-18

Sources 11

ChEMBL, through Open TargetsCC BY-SA 3.0
ClinicalTrials.govNo license stated
HGNCCC0
iCiteCC BY 4.0
NCBI GenePublic domain (US government)
NIH RePORTER's grant and paper linksPublic domain
Open TargetsCC0 1.0
PMC's ID filePublic domain (US government)
PubMedNLM's terms
PubTator 3Public domain
UniProtCC BY 4.0

Each source's terms

ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
ClinicalTrials.govnone stated
HGNCCC0: https://www.genenames.org/about/license/
iCiteCC BY 4.0
NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
NIH RePORTER's grant and paper linksPublic domain (NIH RePORTER)
Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
PMC's ID fileNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
PubMedNLM's terms
PubTator 3Public domain
UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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