Paper27453045
A Conserved Motif Provides Binding Specificity to the PP2A-B56 Phosphatase.
Hertz EPT and 7 others. Mol Cell, 2016. Cited by 244 papers, by iCite.
11 sourcespapers-2026-11-12-0.1.0
Download JSON
Cite this record
ConductScience Library. A Conserved Motif Provides Binding Specificity to the PP2A-B56 Phosphatase. Papers, record 27453045. Release papers-2026-11-12-0.1.0, 12 Nov 2026. https://conductscience.org/library/papers/27453045
Paper
PubMed's record of the paper, with iCite's citation figures. No abstract is shown.
Topics18
NLM's MeSH indexing of the paper, its major topics first.
| MeSH term | Major |
|---|---|
| Protein Phosphatase 2 | Major topic |
| Amino Acid Sequence | |
| Animals | |
| Binding Sites | |
| Computational Biology | |
| Conserved Sequence | |
| Databases, Protein | |
| Forkhead Box Protein O3 | |
| GTPase-Activating Proteins | |
| HeLa Cells | |
| Humans | |
| Molecular Docking Simulation | |
| Phosphorylation | |
| Protein Binding | |
| Protein Interaction Domains and Motifs | |
| Recombinant Fusion Proteins | |
| Substrate Specificity | |
| Transfection |
Source PubMed
Comments and corrections1
PubMed's comments and corrections, NLM's own indexing: retractions first, then expressions of concern, errata and updates, and comments last.
| Kind | PMID | Title | In Papers |
|---|---|---|---|
| Comment in | 27,507,207 | Cell signalling: The motif behind PP2A-B56 specificity. | https://conductscience.org/library/papers/27507207 |
Source PubMed
Cited by189
The papers in our copy of PubMed whose reference list names this one, newest first. iCite, which reads more sources, counts 244 citations.
| PMID | Title | Journal | Year | In Papers | Source |
|---|---|---|---|---|---|
| 42,907,605 | Activator mimicry by PP6 regulatory subunits directs Aurora A dephosphorylation in mitosis. | EMBO J | 2026 | https://conductscience.org/library/papers/42907605 | PubMed |
| 42,630,699 | A case report of a novel de novo variant in PPP2CA causing a neurodevelopmental disorder and epilepsy. | Front Psychiatry | 2026 | https://conductscience.org/library/papers/42630699 | PubMed |
| 42,315,833 | A functional map of phosphoprotein phosphatase regulation identifies an evolutionarily conserved reductase for the catalytic metal ions. | Nat Commun | 2026 | https://conductscience.org/library/papers/42315833 | PubMed |
| 42,190,811 | Liprin-α family proteins and their cellular functions. | J Biol Chem | 2026 | https://conductscience.org/library/papers/42190811 | PubMed |
| 42,138,961 | The Host Cell Factor Phosphatase-2A Subunit PR130 Restricts Replication of Herpes Simplex Virus Type-1. | Adv Sci (Weinh) | 2026 | https://conductscience.org/library/papers/42138961 | PubMed |
| 42,126,139 | Emergent Nonlinearity in Active Molecular Chemotaxis. | ACS Nano | 2026 | https://conductscience.org/library/papers/42126139 | PubMed |
| 42,115,626 | PPP2R2C confers radioresistance in nasopharyngeal carcinoma by suppressing ferroptosis via RPS27L stabilization. | Cell Death Dis | 2026 | https://conductscience.org/library/papers/42115626 | PubMed |
| 41,965,447 | Suppression of PP2A-B56α drives EMT in EGFR mutant non-small cell lung cancer. | Oncogene | 2026 | https://conductscience.org/library/papers/41965447 | PubMed |
| 41,841,343 | Dual-site phosphorylation of SLX4 stabilizes the SLX4-MUS81 interface to promote mitotic SMX assembly and genome protection. | Nucleic Acids Res | 2026 | https://conductscience.org/library/papers/41841343 | PubMed |
| 41,818,150 | Switching of the c-Myc protein degradation pathway depending on the PP2A-B55α complex levels. | Proc Natl Acad Sci U S A | 2026 | https://conductscience.org/library/papers/41818150 | PubMed |
| 41,817,770 | Decoding Cdk1 control: from mitotic thresholds to meiotic specificity. | Chromosome Res | 2026 | https://conductscience.org/library/papers/41817770 | PubMed |
| 41,805,761 | The adeno-associated virus Rep proteins target PP4:SMEK1 by preventing substrate recruitment. | PLoS Pathog | 2026 | https://conductscience.org/library/papers/41805761 | PubMed |
| 41,437,840 | Structural bases of signal generation and transduction by the SPS amino acid sensor of Saccharomyces cerevisiae. | G3 (Bethesda) | 2026 | https://conductscience.org/library/papers/41437840 | PubMed |
| 41,315,219 | AMPK phosphorylates WIP1 to promote DNA repair and radioresistance in cancer cells. | Cell Death Dis | 2025 | https://conductscience.org/library/papers/41315219 | PubMed |
| 41,285,957 | Phosphatase specificity influences phosphorylation timing of CDK substrates during the cell cycle. | Nat Commun | 2025 | https://conductscience.org/library/papers/41285957 | PubMed |
| 41,146,310 | Targeting PP2A in cancer: an underrated option. | J Exp Clin Cancer Res | 2025 | https://conductscience.org/library/papers/41146310 | PubMed |
| 41,081,447 | Protein phosphatase 2A (PP2A) function in male germ cells and its importance for male fertility. | Endocr Connect | 2025 | https://conductscience.org/library/papers/41081447 | PubMed |
| 41,047,934 | Identification of locally activated spindle-associated proteins in oocytes uncovers a phosphatase-driven mechanism. | J Cell Sci | 2025 | https://conductscience.org/library/papers/41047934 | PubMed |
| 41,042,873 | The PP2A-B55α phosphatase is a master regulator of mitochondrial degradation and biogenesis. | Sci Adv | 2025 | https://conductscience.org/library/papers/41042873 | PubMed |
| 40,897,470 | Amino acid-dependent TSC2 dephosphorylation by lysosome-PP2A regulates mTORC1 signaling transduction. | Life Sci Alliance | 2025 | https://conductscience.org/library/papers/40897470 | PubMed |
Genes3
The genes the Gene search release ties to the paper: Swiss-Prot's references first, then PubTator's text mining.
| Gene | NCBI Gene ID | Linked by | In Genes | Source |
|---|---|---|---|---|
| FOXO3 | 2,309 | PubTator's text mining | https://conductscience.org/library/genes/2309 | NCBI Gene |
| NEWENTRY | 192,343 | PubTator's text mining | https://conductscience.org/library/genes/192343 | NCBI Gene |
| PTPA | 5,524 | PubTator's text mining | https://conductscience.org/library/genes/5524 | NCBI Gene |
Data dates
The date of each source this release read.
- Trials
- 2026-11-12
- Gene search
- 2026-11-11
- Pipelines
- 2026-09-18
None in this release
- Grants
- Trials
- References
- Drugs
- Data
Sources 11
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- HGNCCC0
- iCiteCC BY 4.0
- NCBI GenePublic domain (US government)
- NIH RePORTER's grant and paper linksPublic domain
- Open TargetsCC0 1.0
- PMC's ID filePublic domain (US government)
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- HGNCCC0: https://www.genenames.org/about/license/
- iCiteCC BY 4.0
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH RePORTER's grant and paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PMC's ID fileNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this paper from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/papers/v1/27453045
GET https://conductscience.org/api/papers/v1/27453045/cited_by?page=2