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Paper · 28337145

Dioscin Protects ANIT-Induced Intrahepatic Cholestasis Through Regulating Transporters, Apoptosis and Oxidative Stress.

Yao H and 9 others. Front Pharmacol, 2017. Cited by 30 papers, by iCite.

11 sourcespapers-2026-11-12-0.1.0

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ConductScience Library. Dioscin Protects ANIT-Induced Intrahepatic Cholestasis Through Regulating Transporters, Apoptosis and Oxidative Stress. Papers, record 28337145. Release papers-2026-11-12-0.1.0, 12 Nov 2026. https://conductscience.org/library/papers/28337145

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Paper

PubMed's record of the paper, with iCite's citation figures. No abstract is shown.

Title
Dioscin Protects ANIT-Induced Intrahepatic Cholestasis Through Regulating Transporters, Apoptosis and Oxidative Stress.
PubMed
Journal
Front Pharmacol
PubMed
Year
2017
PubMed
Publication types
Journal Article
PubMed
Citations, by iCite
30
iCite
Relative citation ratio, by iCite
1.3
iCite
Revised in PubMed
2022-04-08
PubMed

Authors10

The authors in the order PubMed's record lists them, with the ORCID iDs it states.

OrderAuthorForenameKindORCID iD
1Yao HHong
2Xu YYouwei
3Yin LLianhong
4Tao XXufeng
5Xu LLina
6Qi YYan
7Han XXu
8Sun PPengyuan
9Liu KKexin
10Peng JJinyong

Source PubMed

Topics0

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None in this release.

Grants0

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None in this release.

Trials0

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None in this release.

Comments and corrections0

PubMed's comments and corrections, NLM's own indexing: retractions first, then expressions of concern, errata and updates, and comments last.

None in this release.

References55

The papers the reference list in PubMed's record names, those in our copy of PubMed, in the list's order.

OrderPMIDTitleJournalYearIn PapersSource
112,526,835Synthesis of monomethylated dioscin derivatives and their antitumor activities.Carbohydr Res2003https://conductscience.org/library/papers/12526835PubMed
222,005,833Hepatoprotective action of Radix Paeoniae Rubra aqueous extract against CCl4-induced hepatic damage.Molecules2011https://conductscience.org/library/papers/22005833PubMed
324,987,427Large dosage of chishao in formulae for cholestatic hepatitis: a systematic review and meta-analysis.Evid Based Complement Alternat Med2014https://conductscience.org/library/papers/24987427PubMed
426,806,614Serum Metabolomic Profiling in a Rat Model Reveals Protective Function of Paeoniflorin Against ANIT Induced Cholestasis.Phytother Res2016https://conductscience.org/library/papers/26806614PubMed
515,970,352Oxidative stress and apoptosis in fetal rat liver induced by maternal cholestasis. Protective effect of ursodeoxycholic acid.J Hepatol2005https://conductscience.org/library/papers/15970352PubMed
627,155,058Dioscin reduces ovariectomy-induced bone loss by enhancing osteoblastogenesis and inhibiting osteoclastogenesis.Pharmacol Res2016https://conductscience.org/library/papers/27155058PubMed
718,601,945Regulation of glutathione synthesis.Mol Aspects Med2009https://conductscience.org/library/papers/18601945PubMed
816,858,290Kupffer cell-mediated downregulation of hepatic transporter expression in rat hepatic ischemia-reperfusion.Transplantation2006https://conductscience.org/library/papers/16858290PubMed
915,505,592The importance of redox state in liver damage.Ann Hepatol2004https://conductscience.org/library/papers/15505592PubMed
1012,763,363Adaptive changes in hepatobiliary transporter expression in primary biliary cirrhosis.J Hepatol2003https://conductscience.org/library/papers/12763363PubMed

1 to 10 of 55

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Cited by17

The papers in our copy of PubMed whose reference list names this one, newest first. iCite, which reads more sources, counts 30 citations.

PMIDTitleJournalYearIn PapersSource
42,643,637Dioscin in liver diseases: pharmacological mechanisms, translational potential and future perspectives.Front Pharmacol2026https://conductscience.org/library/papers/42643637PubMed
42,287,535Galactosylated Solid Lipid Nanoparticles with Swertiamarin Alleviate Cholestiatic Liver Injury via Enhancing the SIRT1/Nrf2 Pathway.Appl Biochem Biotechnol2026https://conductscience.org/library/papers/42287535PubMed
40,244,450Synergistic action of cilnidipine and bexarotene in mitigating cholestatic liver damage: role of FXR signaling cascade.Naunyn Schmiedebergs Arch Pharmacol2025https://conductscience.org/library/papers/40244450PubMed
40,009,169Novel insights into bexarotene's role in preventing cholestasis: mechanisms and implications.Naunyn Schmiedebergs Arch Pharmacol2025https://conductscience.org/library/papers/40009169PubMed
39,989,470Hepatoprotective Effects of Cilnidipine in Cholestatic Liver Disease: Role of FXR and NRF2 Signalling.J Exp Pharmacol2025https://conductscience.org/library/papers/39989470PubMed
39,666,011Based on network pharmacology, the mechanism of Dioscin in alleviating renal tubular epithelial cell injury induced by calcium oxalate crystals was explored.Urolithiasis2024https://conductscience.org/library/papers/39666011PubMed
39,220,868The role of botanical triterpenoids and steroids in bile acid metabolism, transport, and signaling: Pharmacological and toxicological implications.Acta Pharm Sin B2024https://conductscience.org/library/papers/39220868PubMed
38,523,644The anti-cholestatic effects of Coptis chinensis Franch. alone and combined with Tetradium ruticarpum (A. Jussieu) T. G. Hartley: dual effects on fecal metabolism and microbial diversity.Front Pharmacol2024https://conductscience.org/library/papers/38523644PubMed
37,055,831Dioscin alleviates the progression of osteoarthritis: an in vitro and in vivo study.J Inflamm (Lond)2023https://conductscience.org/library/papers/37055831PubMed
35,845,569San-Huang-Chai-Zhu Formula Ameliorates Liver Injury in Intrahepatic Cholestasis through Suppressing SIRT1/PGC-1α-Regulated Mitochondrial Oxidative Stress.Evid Based Complement Alternat Med2022https://conductscience.org/library/papers/35845569PubMed

1 to 10 of 17

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Genes0

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None in this release.

Drugs0

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None in this release.

Data0

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None in this release.

Data dates

The date of each source this release read.

PubMed
2026-11-06
PubMed
iCite
2026-11-05
iCite
PMC's ID file
2026-11-05
PMC's ID file
NIH RePORTER's grant and paper links
2026-11-01
NIH RePORTER's grant and paper links
Trials
2026-11-12
Gene search
2026-11-11
Pipelines
2026-09-18

Sources 11

  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • HGNCCC0
  • iCiteCC BY 4.0
  • NCBI GenePublic domain (US government)
  • NIH RePORTER's grant and paper linksPublic domain
  • Open TargetsCC0 1.0
  • PMC's ID filePublic domain (US government)
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • HGNCCC0: https://www.genenames.org/about/license/
  • iCiteCC BY 4.0
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH RePORTER's grant and paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PMC's ID fileNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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