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Paper · 301251

Neonatally tolerant mice fail to react against virus-infected tolerated cells.

Zinkernagel RM and 3 others. Nature, 1977. Cited by 22 papers, by iCite.

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ConductScience Library. Neonatally tolerant mice fail to react against virus-infected tolerated cells. Papers, record 301251. Release papers-2026-11-12-0.1.0, 12 Nov 2026. https://conductscience.org/library/papers/301251

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Paper

PubMed's record of the paper, with iCite's citation figures. No abstract is shown.

Title
Neonatally tolerant mice fail to react against virus-infected tolerated cells.
PubMed
Journal
Nature
PubMed
Year
1977
PubMed
Publication types
Journal Article, Research Support, U.S. Gov't, P.H.S.
PubMed
Citations, by iCite
22
iCite
Relative citation ratio, by iCite
0.49
iCite
Revised in PubMed
2026-10-28
PubMed

Authors4

The authors in the order PubMed's record lists them, with the ORCID iDs it states.

OrderAuthorForenameKindORCID iD
1Zinkernagel RMR M
2Callahan GNG N
3Streilein JWJ W
4Klein JJ

Source PubMed

Topics13

NLM's MeSH indexing of the paper, its major topics first.

MeSH termMajor
Histocompatibility AntigensMajor topic
Immune ToleranceMajor topic
Immunity, CellularMajor topic
T-LymphocytesMajor topic
Vaccinia virusMajor topic
Animals
Animals, Newborn
Antigens, Viral
Binding Sites
Cytotoxicity Tests, Immunologic
Immunosuppression Therapy
Mice
Radiation Chimera

Source PubMed

Grants0

Each grant PubMed's record writes, matched to the NIH project NIH's grant and paper links name for this paper, and each of those links the record does not write.

None in this release.

Trials0

The trials whose ClinicalTrials.gov record lists the paper, and the trial numbers the paper's PubMed record names.

None in this release.

Comments and corrections0

PubMed's comments and corrections, NLM's own indexing: retractions first, then expressions of concern, errata and updates, and comments last.

None in this release.

References10

The papers the reference list in PubMed's record names, those in our copy of PubMed, in the list's order.

OrderPMIDTitleJournalYearIn PapersSource
158,463Specificity of virus-immune effector T cells for H-2K or H-2D compatible interactions: implications for H-antigen diversity.Transplant Rev1976https://conductscience.org/library/papers/58463PubMed
21,078,719Genes required for cytotoxicity against virus-infected target cells in K and D regions of H-2 complex.Nature1975https://conductscience.org/library/papers/1078719PubMed
34,547,543Immunological surveillance against altered self components by sensitised T lymphocytes in lymphocytic choriomeningitis.Nature1974https://conductscience.org/library/papers/4547543PubMed
44,133,807Restriction of in vitro T cell-mediated cytotoxicity in lymphocytic choriomeningitis within a syngeneic or semiallogeneic system.Nature1974https://conductscience.org/library/papers/4133807PubMed
55,075,626Aliotypic antibodies.Transplant Rev1972https://conductscience.org/library/papers/5075626PubMed
6136,607Products of the major histocompatibility complex and their relationship to the immune response.Nature1976https://conductscience.org/library/papers/136607PubMed
752,176Idiotype-positive T lymphocytes.Scand J Immunol1975https://conductscience.org/library/papers/52176PubMed
8185,298Characterization of Ia antigens in mouse serum.J Immunol1976https://conductscience.org/library/papers/185298PubMed
91,083,956Cytotoxic T lymphocytes recognise allogeneic tolerated TNP-conjugated cells.Nature1976https://conductscience.org/library/papers/1083956PubMed
101,083,955Virus-specific T-cell-mediated cytotoxicity across the H-2 barrier to virus-altered alloantigen.Nature1976https://conductscience.org/library/papers/1083955PubMed

Cited by7

The papers in our copy of PubMed whose reference list names this one, newest first. iCite, which reads more sources, counts 22 citations.

PMIDTitleJournalYearIn PapersSource
9,482,904Prevention of Th2-mediated murine allergic airways disease by soluble antigen administration in the neonate.Proc Natl Acad Sci U S A1998https://conductscience.org/library/papers/9482904PubMed
6,213,732Genetic control of the immune response to myoglobins. Both low and high responder T cells tolerant to the other major histocompatibility complex help high but not low responder B cells.J Exp Med1982https://conductscience.org/library/papers/6213732PubMed
6,161,883Reactivity of neuro-antigen-sensitized lymphocytes against syngeneic, allogeneic and tolerated allogeneic neural tissue.Immunology1981https://conductscience.org/library/papers/6161883PubMed
310,553H-2 complementation in anti-H-Y cytotoxic T-cell responses can occur in chimeric mice.Proc Natl Acad Sci U S A1978https://conductscience.org/library/papers/310553PubMed
305,460The lymphoreticular system in triggering virus plus self-specific cytotoxic T cells: evidence for T help.J Exp Med1978https://conductscience.org/library/papers/305460PubMed
305,459On the thymus in the differentiation of "H-2 self-recognition" by T cells: evidence for dual recognition?J Exp Med1978https://conductscience.org/library/papers/305459PubMed
304,527Cytotoxic T cells learn specificity for self H-2 during differentiation in the thymus.Nature1978https://conductscience.org/library/papers/304527PubMed

Genes0

The genes the Gene search release ties to the paper: Swiss-Prot's references first, then PubTator's text mining.

None in this release.

Drugs0

The drugs whose trials, in the Pipelines release, list the paper.

None in this release.

Data0

The data bank entries PubMed's record names. Trial numbers are under Trials.

None in this release.

Data dates

The date of each source this release read.

PubMed
2026-11-06
PubMed
iCite
2026-11-05
iCite
PMC's ID file
2026-11-05
PMC's ID file
NIH RePORTER's grant and paper links
2026-11-01
NIH RePORTER's grant and paper links
Trials
2026-11-12
Gene search
2026-11-11
Pipelines
2026-09-18

Sources 11

  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • HGNCCC0
  • iCiteCC BY 4.0
  • NCBI GenePublic domain (US government)
  • NIH RePORTER's grant and paper linksPublic domain
  • Open TargetsCC0 1.0
  • PMC's ID filePublic domain (US government)
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • HGNCCC0: https://www.genenames.org/about/license/
  • iCiteCC BY 4.0
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH RePORTER's grant and paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PMC's ID fileNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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