Paper · 301548

Ontogeny of Ia and IgD on IgM-bearing B lymphocytes in mice.

Kearney JF and 5 others. J Exp Med, 1977. Cited by 181 papers, by iCite.

11 sourcespapers-2026-11-12-0.1.0

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ConductScience Library. Ontogeny of Ia and IgD on IgM-bearing B lymphocytes in mice. Papers, record 301548. Release papers-2026-11-12-0.1.0, 12 Nov 2026. https://conductscience.org/library/papers/301548

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Paper

PubMed's record of the paper, with iCite's citation figures. No abstract is shown.

Title: Ontogeny of Ia and IgD on IgM-bearing B lymphocytes in mice.; PubMed
Journal: J Exp Med; PubMed
Year: 1977; PubMed
Publication types: Journal Article, Research Support, U.S. Gov't, P.H.S.; PubMed
PubMed: https://pubmed.ncbi.nlm.nih.gov/301548/; PubMed
DOI: https://doi.org/10.1084/jem.146.1.297; PubMed
PMC: https://pmc.ncbi.nlm.nih.gov/articles/PMC2180751/; PubMed
The journal: https://conductscience.org/library/journal-index/2985109R; PubMed
Citations, by iCite: 181; iCite
Relative citation ratio, by iCite: 3.18; iCite
Revised in PubMed: 2019-05-08; PubMed

Authors6

The authors in the order PubMed's record lists them, with the ORCID iDs it states.

Order	Author	Forename
1	Kearney JF	J F
2	Cooper MD	M D
3	Klein J	J
4	Abney ER	E R
5	Parkhouse RM	R M
6	Lawton AR	A R

Source PubMed

Topics16

NLM's MeSH indexing of the paper, its major topics first.

MeSH term	Major
B-Lymphocytes	Major topic
Histocompatibility Antigens	Major topic
Immunoglobulin D	Major topic
Immunoglobulin M	Major topic
Aging
Animals
Bone Marrow
Bone Marrow Cells
Cell Division
Lipopolysaccharides
Liver
Mice
Mice, Inbred Strains
Plasma Cells
Receptors, Antigen, B-Cell
Spleen

Source PubMed

Grants1

Each grant PubMed's record writes, matched to the NIH project NIH's grant and paper links name for this paper, and each of those links the record does not write.

Grant, as the record writes it	Agency	Country	NIH project	Stated by
R01 AI014782	NIAID NIH HHS	United States	R01AI014782	PubMed

Source NIH RePORTER

Trials0

The trials whose ClinicalTrials.gov record lists the paper, and the trial numbers the paper's PubMed record names.

None in this release.

Comments and corrections0

PubMed's comments and corrections, NLM's own indexing: retractions first, then expressions of concern, errata and updates, and comments last.

None in this release.

References17

The papers the reference list in PubMed's record names, those in our copy of PubMed, in the list's order.

Order	PMID	Title	Journal	Year	In Papers	Source
1	4,128,439	A mouse B-cell alloantigen determined by gene(s) linked to the major histocompatibility complex.	J Exp Med	1973	https://conductscience.org/library/papers/4128439	PubMed
2	4,215,039	Candidate for immunoglobulin D present on murine B lymphocytes.	Nature	1974	https://conductscience.org/library/papers/4215039	PubMed
3	58,052	In vitro tolerance induction of neonatal murine B cells.	J Exp Med	1976	https://conductscience.org/library/papers/58052	PubMed
4	55,062	The histocompatibility-linked immune response genes.	Adv Cancer Res	1975	https://conductscience.org/library/papers/55062	PubMed
5	47,889	Evidence for the clonal abortion theory of B-lymphocyte tolerance.	J Exp Med	1975	https://conductscience.org/library/papers/47889	PubMed
6	4,542,609	Enumeration and analysis of antibody-forming cell precursors in the neonatal mouse.	J Immunol	1973	https://conductscience.org/library/papers/4542609	PubMed
7	4,547,437	Evidence for the expression of Ia (H-2-associated) antigens on thymus-derived lymphocytes.	J Exp Med	1974	https://conductscience.org/library/papers/4547437	PubMed
8	811,749	The allogeneic bisection of carrier-specific enhancement of monoclonal B-cell responses.	J Exp Med	1975	https://conductscience.org/library/papers/811749	PubMed
9	811,748	Differences in susceptibility of mature and immature mouse B lymphocytes to anti-immunoglobulin-induced immunoglobulin suppression in vitro. Possible implications for B-cell tolerance to self.	J Exp Med	1975	https://conductscience.org/library/papers/811748	PubMed
10	814,466	Early production of intracellular IgM by B-lymphocyte precursors in mouse.	Nature	1976	https://conductscience.org/library/papers/814466	PubMed

1 to 10 of 17

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Cited by32

The papers in our copy of PubMed whose reference list names this one, newest first. iCite, which reads more sources, counts 181 citations.

PMID	Title	Journal	Year	In Papers	Source
31,213,084	Splenectomy fails to attenuate immuno-hematologic changes after rodent vertical sleeve gastrectomy.	Exp Biol Med (Maywood)	2019	https://conductscience.org/library/papers/31213084	PubMed
26,092,524	The immune system as a self-centered network of lymphocytes.	Immunol Lett	2015	https://conductscience.org/library/papers/26092524	PubMed
11,867,763	Identification of a germ-line pro-B cell subset that distinguishes the fetal/neonatal from the adult B cell development pathway.	Proc Natl Acad Sci U S A	2002	https://conductscience.org/library/papers/11867763	PubMed
10,727,464	Gene dose-dependent maturation and receptor editing of B cells expressing immunoglobulin (Ig)G1 or IgM/IgG1 tail antigen receptors.	J Exp Med	2000	https://conductscience.org/library/papers/10727464	PubMed
8,757,957	Differential expression of CD22 (Lyb8) on murine B cells.	Int Immunol	1996	https://conductscience.org/library/papers/8757957	PubMed
7,913,950	Major histocompatibility complex class II expression distinguishes two distinct B cell developmental pathways during ontogeny.	J Exp Med	1994	https://conductscience.org/library/papers/7913950	PubMed
7,590,872	Human lactoferrin induces phenotypic and functional changes in murine splenic B cells.	Immunology	1995	https://conductscience.org/library/papers/7590872	PubMed
7,037,618	Activation of polyclonal antibody responses by a synthetic serum thymic factor (FTS) in CBA/N mice.	Immunology	1982	https://conductscience.org/library/papers/7037618	PubMed
7,020,898	Surface receptors on lymphoreticular cells: sensory devices for host recognition of foreign antigens and neoplasia.	Can Med Assoc J	1980	https://conductscience.org/library/papers/7020898	PubMed
6,973,760	Expression of cell surface markers after human B lymphocyte activation.	Proc Natl Acad Sci U S A	1981	https://conductscience.org/library/papers/6973760	PubMed

1 to 10 of 32

See all 32 cited by

Genes0

The genes the Gene search release ties to the paper: Swiss-Prot's references first, then PubTator's text mining.

None in this release.

Drugs0

The drugs whose trials, in the Pipelines release, list the paper.

None in this release.

Data0

The data bank entries PubMed's record names. Trial numbers are under Trials.

None in this release.

Data dates

The date of each source this release read.

PubMed: 2026-11-06; PubMed
iCite: 2026-11-05; iCite
PMC's ID file: 2026-11-05; PMC's ID file
NIH RePORTER's grant and paper links: 2026-11-01; NIH RePORTER's grant and paper links
Trials: 2026-11-12
Gene search: 2026-11-11
Pipelines: 2026-09-18

Sources 11

ChEMBL, through Open TargetsCC BY-SA 3.0
ClinicalTrials.govNo license stated
HGNCCC0
iCiteCC BY 4.0
NCBI GenePublic domain (US government)
NIH RePORTER's grant and paper linksPublic domain
Open TargetsCC0 1.0
PMC's ID filePublic domain (US government)
PubMedNLM's terms
PubTator 3Public domain
UniProtCC BY 4.0

Each source's terms

ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
ClinicalTrials.govnone stated
HGNCCC0: https://www.genenames.org/about/license/
iCiteCC BY 4.0
NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
NIH RePORTER's grant and paper linksPublic domain (NIH RePORTER)
Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
PMC's ID fileNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
PubMedNLM's terms
PubTator 3Public domain
UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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