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Paper · 30264682

Antiproliferative Effects of Cynaropicrin on Anaplastic Thyroid Cancer Cells.

Lepore SM and 7 others. Endocr Metab Immune Disord Drug Targets, 2019. Cited by 23 papers, by iCite.

11 sourcespapers-2026-11-12-0.1.0

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ConductScience Library. Antiproliferative Effects of Cynaropicrin on Anaplastic Thyroid Cancer Cells. Papers, record 30264682. Release papers-2026-11-12-0.1.0, 12 Nov 2026. https://conductscience.org/library/papers/30264682

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Paper

PubMed's record of the paper, with iCite's citation figures. No abstract is shown.

Title
Antiproliferative Effects of Cynaropicrin on Anaplastic Thyroid Cancer Cells.
PubMed
Journal
Endocr Metab Immune Disord Drug Targets
PubMed
Year
2019
PubMed
Publication types
Journal Article
PubMed
Citations, by iCite
23
iCite
Relative citation ratio, by iCite
1.24
iCite
Revised in PubMed
2019-05-17
PubMed

Authors8

The authors in the order PubMed's record lists them, with the ORCID iDs it states.

OrderAuthorForenameKindORCID iD
1Lepore SMSaverio M
2Maggisano VValentina
3Lombardo GEGiovanni E
4Maiuolo JJessica
5Mollace VVincenzo
6Bulotta SStefania
7Russo DDiego
8Celano MMarilena

Source PubMed

Topics16

NLM's MeSH indexing of the paper, its major topics first.

MeSH termMajor
Antineoplastic Agents, PhytogenicMajor topic
LactonesMajor topic
SesquiterpenesMajor topic
Thyroid Carcinoma, AnaplasticMajor topic
Thyroid NeoplasmsMajor topic
Antioxidants
Cell Cycle Checkpoints
Cell Line, Tumor
Cell Survival
Humans
Lipid Peroxidation
Malondialdehyde
NF-kappa B
Phosphorylation
Reactive Oxygen Species
STAT3 Transcription Factor

Source PubMed

Grants0

Each grant PubMed's record writes, matched to the NIH project NIH's grant and paper links name for this paper, and each of those links the record does not write.

None in this release.

Trials0

The trials whose ClinicalTrials.gov record lists the paper, and the trial numbers the paper's PubMed record names.

None in this release.

Comments and corrections0

PubMed's comments and corrections, NLM's own indexing: retractions first, then expressions of concern, errata and updates, and comments last.

None in this release.

References0

The papers the reference list in PubMed's record names, those in our copy of PubMed, in the list's order.

None in this release.

Cited by19

The papers in our copy of PubMed whose reference list names this one, newest first. iCite, which reads more sources, counts 23 citations.

PMIDTitleJournalYearIn PapersSource
42,278,321Modulation of NF-κB and TLR Signaling Pathways and Complement Components in Ovine Maternal Thyroid During Early Pregnancy.Int J Mol Sci2026https://conductscience.org/library/papers/42278321PubMed
42,120,505Lysosomal vulnerability as a therapeutic target in thyroid cancer using fucoidan nanoparticles.Sci Rep2026https://conductscience.org/library/papers/42120505PubMed
41,647,454The effect of cynaropicrin, a sesquiterpene lactone, on the migratory properties of triple-negative breast cancer cells and the underlying mechanisms.Avicenna J Phytomed2026https://conductscience.org/library/papers/41647454PubMed
40,732,979The Potential of Nutraceutical Supplementation in Counteracting Cancer Development and Progression: A Pathophysiological Perspective.Nutrients2025https://conductscience.org/library/papers/40732979PubMed
40,520,862Cynaropicrin induces the apoptosis of colorectal cancer cells by elevating reactive oxygen species and activating the JNK/p38 MAPK.Am J Cancer Res2025https://conductscience.org/library/papers/40520862PubMed
40,372,575Natural sesquiterpene lactones in prostate cancer therapy: mechanisms and sources.Med Oncol2025https://conductscience.org/library/papers/40372575PubMed
40,295,200Cynaropicrin Suppresses Cell Proliferation by Inducing Mitophagy through p38 MAPK-Mediated Mitochondrial ROS Generation in Human Hepatocellular Carcinoma Cells.J Microbiol Biotechnol2025https://conductscience.org/library/papers/40295200PubMed
39,200,219The Protective Role of Troxerutin (Trox) in Counteracting Anaplastic Thyroid Carcinoma (ATC) Progression.Biomedicines2024https://conductscience.org/library/papers/39200219PubMed
39,066,893Cynaropicrin, a sesquiterpene lactone, triggers apoptotic cell death in triple negative breast cancer cells.Mol Biol Rep2024https://conductscience.org/library/papers/39066893PubMed
38,929,492Selenoprotein-P1 (SEPP1) Expression in Human Proximal Tubule Cells after Ischemia-Reperfusion Injury: An In Vitro Model.Medicina (Kaunas)2024https://conductscience.org/library/papers/38929492PubMed

1 to 10 of 19

See all 19 cited by

Genes2

The genes the Gene search release ties to the paper: Swiss-Prot's references first, then PubTator's text mining.

GeneNCBI Gene IDLinked byIn GenesSource
NFKB14,790PubTator's text mininghttps://conductscience.org/library/genes/4790NCBI Gene
STAT36,774PubTator's text mininghttps://conductscience.org/library/genes/6774NCBI Gene

Drugs0

The drugs whose trials, in the Pipelines release, list the paper.

None in this release.

Data0

The data bank entries PubMed's record names. Trial numbers are under Trials.

None in this release.

Data dates

The date of each source this release read.

PubMed
2026-11-06
PubMed
iCite
2026-11-05
iCite
PMC's ID file
2026-11-05
PMC's ID file
NIH RePORTER's grant and paper links
2026-11-01
NIH RePORTER's grant and paper links
Trials
2026-11-12
Gene search
2026-11-11
Pipelines
2026-09-18

Sources 11

  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • HGNCCC0
  • iCiteCC BY 4.0
  • NCBI GenePublic domain (US government)
  • NIH RePORTER's grant and paper linksPublic domain
  • Open TargetsCC0 1.0
  • PMC's ID filePublic domain (US government)
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • HGNCCC0: https://www.genenames.org/about/license/
  • iCiteCC BY 4.0
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH RePORTER's grant and paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PMC's ID fileNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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