Paper358200
Nucleotide sequence of the ampicillin resistance gene of Escherichia coli plasmid pBR322.
Sutcliffe JG. Proc Natl Acad Sci U S A, 1978. Cited by 782 papers, by iCite.
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ConductScience Library. Nucleotide sequence of the ampicillin resistance gene of Escherichia coli plasmid pBR322. Papers, record 358200. Release papers-2026-11-12-0.1.0, 12 Nov 2026. https://conductscience.org/library/papers/358200
Paper
PubMed's record of the paper, with iCite's citation figures. No abstract is shown.
- Title
- Nucleotide sequence of the ampicillin resistance gene of Escherichia coli plasmid pBR322.
- PubMed
Topics7
NLM's MeSH indexing of the paper, its major topics first.
| MeSH term | Major |
|---|---|
| Ampicillin | Major topic |
| Escherichia coli | Major topic |
| Genes | Major topic |
| Penicillin Resistance | Major topic |
| Plasmids | Major topic |
| Base Sequence | |
| beta-Lactamases |
Source PubMed
References20
The papers the reference list in PubMed's record names, those in our copy of PubMed, in the list's order.
| Order | PMID | Title | Journal | Year | In Papers | Source |
|---|---|---|---|---|---|---|
| 1 | 358,199 | Partial amino acid sequence of penicillinase coded by Escherichia coli plasmid R6K. | Proc Natl Acad Sci U S A | 1978 | https://conductscience.org/library/papers/358199 | PubMed |
| 2 | 344,137 | Construction and characterization of new cloning vehicles. II. A multipurpose cloning system. | Gene | 1977 | https://conductscience.org/library/papers/344137 | PubMed |
| 3 | 344,136 | Construction and characterization of new cloning vehicles. I. Ampicillin-resistant derivatives of the plasmid pMB9. | Gene | 1977 | https://conductscience.org/library/papers/344136 | PubMed |
| 4 | 265,521 | A new method for sequencing DNA. | Proc Natl Acad Sci U S A | 1977 | https://conductscience.org/library/papers/265521 | PubMed |
| 5 | 593,347 | Sequence of Cro gene of bacteriophage lambda. | Nature | 1977 | https://conductscience.org/library/papers/593347 | PubMed |
| 6 | 870,828 | Nucleotide sequence of bacteriophage phi X174 DNA. | Nature | 1977 | https://conductscience.org/library/papers/870828 | PubMed |
| 7 | 796,732 | Directed selective pressure on a beta-lactamase to analyse molecular changes involved in development of enzyme function. | Nature | 1976 | https://conductscience.org/library/papers/796732 | PubMed |
| 8 | 1,093,168 | Nucleotide sequence of an RNA polymerase binding site at an early T7 promoter. | Proc Natl Acad Sci U S A | 1975 | https://conductscience.org/library/papers/1093168 | PubMed |
| 9 | 4,598,299 | The 3'-terminal sequence of Escherichia coli 16S ribosomal RNA: complementarity to nonsense triplets and ribosome binding sites. | Proc Natl Acad Sci U S A | 1974 | https://conductscience.org/library/papers/4598299 | PubMed |
| 10 | 167,279 | Pleiotropic effects of a DNA adenine methylation mutation (dam-3) in Escherichia coli K12. | Mutat Res | 1975 | https://conductscience.org/library/papers/167279 | PubMed |
| 11 | 5,326,330 | Penicillinase synthesis controlled by infectious R factors in Enterobacteriaceae. | Nature | 1965 | https://conductscience.org/library/papers/5326330 | PubMed |
| 12 | 811,671 | Transfer of proteins across membranes. I. Presence of proteolytically processed and unprocessed nascent immunoglobulin light chains on membrane-bound ribosomes of murine myeloma. | J Cell Biol | 1975 | https://conductscience.org/library/papers/811671 | PubMed |
| 13 | 785,016 | 5-5A crystallographic structure of penicillin beta-lactamase and radius of gyration in solution. | J Mol Biol | 1976 | https://conductscience.org/library/papers/785016 | PubMed |
| 14 | 1,090,574 | Construction of a colicin E1-R factor composite plasmid in vitro: means for amplification of deoxyribonucleic acid. | J Bacteriol | 1975 | https://conductscience.org/library/papers/1090574 | PubMed |
| 15 | 1,091,625 | Origin of the TEM-beta-lactamase gene found on plasmids. | J Bacteriol | 1975 | https://conductscience.org/library/papers/1091625 | PubMed |
| 16 | 1,107,329 | Analytical isoelectric focusing of R factor-determined beta-lactamases: correlation with plasmid compatibility. | J Bacteriol | 1976 | https://conductscience.org/library/papers/1107329 | PubMed |
| 17 | 1,045,010 | The generation of a ColE1-Apr cloning vehicle which allows detection of inserted DNA. | Mol Gen Genet | 1975 | https://conductscience.org/library/papers/1045010 | PubMed |
| 18 | 955,064 | The mapping and sequence determination of the single site in phiX174am3 replicative form DNA cleaved by restriction endonuclease Pst I. | FEBS Lett | 1976 | https://conductscience.org/library/papers/955064 | PubMed |
| 19 | 1,191,297 | In vitro synthesis of hydrophobic penicillinase in extracts of Bacillus licheniforms 749/C. | Biochem Biophys Res Commun | 1975 | https://conductscience.org/library/papers/1191297 | PubMed |
| 20 | 6,054,969 | Mutant drug resistant factors of high transmissibility. | Nature | 1967 | https://conductscience.org/library/papers/6054969 | PubMed |
Cited by375
The papers in our copy of PubMed whose reference list names this one, newest first. iCite, which reads more sources, counts 782 citations.
| PMID | Title | Journal | Year | In Papers | Source |
|---|---|---|---|---|---|
| 42,172,222 | Characteristics of Escherichia coli ST131 strains isolated from dogs and cats with urinary tract infections in a teaching hospital in Taiwan. | PLoS One | 2026 | https://conductscience.org/library/papers/42172222 | PubMed |
| 41,394,159 | Small RNA or oligonucleotide drugs and challenges in evaluating drug-drug interactions. | Front Pharmacol | 2025 | https://conductscience.org/library/papers/41394159 | PubMed |
| 41,251,492 | Impact of synonymous mutations in the blaTEM-3 gene on gene expression and Escherichia coli fitness. | Microbiol Spectr | 2026 | https://conductscience.org/library/papers/41251492 | PubMed |
| 41,028,731 | Escherichia coli phylogeny drives co-amoxiclav resistance through variable expression of TEM-1 beta-lactamase. | Nat Commun | 2025 | https://conductscience.org/library/papers/41028731 | PubMed |
| 39,769,093 | Novel Selectable Marker Sesquiterpenoid Antibiotic Pentalenolactone. | Int J Mol Sci | 2024 | https://conductscience.org/library/papers/39769093 | PubMed |
| 39,604,539 | Characteristics of the extended-spectrum-β-lactamase-producing Escherichia coli isolated from diseased livestock and poultry in Taiwan. | Sci Rep | 2024 | https://conductscience.org/library/papers/39604539 | PubMed |
| 38,576,723 | Development of PCR primers enabling the design of flexible sticky ends for efficient concatenation of long DNA fragments. | RSC Chem Biol | 2024 | https://conductscience.org/library/papers/38576723 | PubMed |
| 38,247,599 | The Klebsiella pneumoniae carbapenemase (KPC) β-Lactamase Has Evolved in Response to Ceftazidime Avibactam. | Antibiotics (Basel) | 2023 | https://conductscience.org/library/papers/38247599 | PubMed |
| 38,227,590 | Occurrence and characteristics of extended-spectrum-β-lactamase- and pAmpC-producing Klebsiella pneumoniae isolated from companion animals with urinary tract infections. | PLoS One | 2024 | https://conductscience.org/library/papers/38227590 | PubMed |
| 38,136,780 | Strategies to Name Metallo-β-Lactamases and Number Their Amino Acid Residues. | Antibiotics (Basel) | 2023 | https://conductscience.org/library/papers/38136780 | PubMed |
| 37,259,383 | Inhibition of Enzymatic Acetylation-Mediated Resistance to Plazomicin by Silver Ions. | Pharmaceuticals (Basel) | 2023 | https://conductscience.org/library/papers/37259383 | PubMed |
| 37,199,645 | Escherichia coli B-Strains Are Intrinsically Resistant to Colistin and Not Suitable for Characterization and Identification of mcr Genes. | Microbiol Spectr | 2023 | https://conductscience.org/library/papers/37199645 | PubMed |
| 36,948,592 | Recombinant Technologies Facilitate Drug Metabolism, Pharmacokinetics, and General Biomedical Research. | Drug Metab Dispos | 2023 | https://conductscience.org/library/papers/36948592 | PubMed |
| 36,832,001 | Engineered Biosensors for Diagnosing Multidrug Resistance in Microbial and Malignant Cells. | Biosensors (Basel) | 2023 | https://conductscience.org/library/papers/36832001 | PubMed |
| 36,169,310 | A Novel FadL Homolog, AltL, Mediates Transport of Long-Chain Alkanes and Fatty Acids in Acinetobacter venetianus RAG-1. | Appl Environ Microbiol | 2022 | https://conductscience.org/library/papers/36169310 | PubMed |
| 35,078,531 | High-resolution genomic surveillance elucidates a multilayered hierarchical transfer of resistance between WWTP- and human/animal-associated bacteria. | Microbiome | 2022 | https://conductscience.org/library/papers/35078531 | PubMed |
| 34,982,550 | Antibiotic-Efficient Genetic Cassette for the TEM-1 β-Lactamase That Improves Plasmid Performance. | ACS Synth Biol | 2022 | https://conductscience.org/library/papers/34982550 | PubMed |
| 34,943,748 | Presence of the Extended-Spectrum-β-Lactamase and Plasmid-Mediated AmpC-Encoding Genes in Escherichia coli from Companion Animals-A Study from a University-Based Veterinary Hospital in Taipei, Taiwan. | Antibiotics (Basel) | 2021 | https://conductscience.org/library/papers/34943748 | PubMed |
| 34,784,042 | Production of Vaccines Using Biological Conjugation. | Methods Mol Biol | 2022 | https://conductscience.org/library/papers/34784042 | PubMed |
| 33,820,762 | Role of Synonymous Mutations in the Evolution of TEM β-Lactamase Genes. | Antimicrob Agents Chemother | 2021 | https://conductscience.org/library/papers/33820762 | PubMed |
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- 2026-11-12
- Gene search
- 2026-11-11
- Pipelines
- 2026-09-18
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- Drugs
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- ClinicalTrials.govNo license stated
- HGNCCC0
- iCiteCC BY 4.0
- NCBI GenePublic domain (US government)
- NIH RePORTER's grant and paper linksPublic domain
- Open TargetsCC0 1.0
- PMC's ID filePublic domain (US government)
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
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- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- HGNCCC0: https://www.genenames.org/about/license/
- iCiteCC BY 4.0
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH RePORTER's grant and paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PMC's ID fileNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
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