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Paper · 359749

Antigen-specific helper factor in man.

Mudawwar FB and 2 others. J Exp Med, 1978. Cited by 63 papers, by iCite.

11 sourcespapers-2026-11-12-0.1.0

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ConductScience Library. Antigen-specific helper factor in man. Papers, record 359749. Release papers-2026-11-12-0.1.0, 12 Nov 2026. https://conductscience.org/library/papers/359749

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Paper

PubMed's record of the paper, with iCite's citation figures. No abstract is shown.

Title
Antigen-specific helper factor in man.
PubMed
Journal
J Exp Med
PubMed
Year
1978
PubMed
Publication types
Journal Article, Research Support, U.S. Gov't, P.H.S.
PubMed
Citations, by iCite
63
iCite
Relative citation ratio, by iCite
1.67
iCite
Revised in PubMed
2019-05-08
PubMed

Authors3

The authors in the order PubMed's record lists them, with the ORCID iDs it states.

OrderAuthorForenameKindORCID iD
1Mudawwar FBF B
2Yunis EJE J
3Geha RSR S

Source PubMed

Topics12

NLM's MeSH indexing of the paper, its major topics first.

MeSH termMajor
Antibody FormationMajor topic
Lymphocyte CooperationMajor topic
T-LymphocytesMajor topic
Tetanus ToxoidMajor topic
B-Lymphocytes
Humans
Immunoglobulin G
Immunoglobulin Idiotypes
Immunosorbent Techniques
Lymphokines
Molecular Weight
Tetanus Antitoxin

Source PubMed

Grants0

Each grant PubMed's record writes, matched to the NIH project NIH's grant and paper links name for this paper, and each of those links the record does not write.

None in this release.

Trials0

The trials whose ClinicalTrials.gov record lists the paper, and the trial numbers the paper's PubMed record names.

None in this release.

Comments and corrections0

PubMed's comments and corrections, NLM's own indexing: retractions first, then expressions of concern, errata and updates, and comments last.

None in this release.

References16

The papers the reference list in PubMed's record names, those in our copy of PubMed, in the list's order.

OrderPMIDTitleJournalYearIn PapersSource
170,054Evidence for two series of B-cell antigens in man and their comparison with HLA-D.Scand J Immunol1977https://conductscience.org/library/papers/70054PubMed
2415,256Molecular variants of human Ia-like antigens.Nature1978https://conductscience.org/library/papers/415256PubMed
3301,172The specificity of T-cell helper factor in man.J Exp Med1977https://conductscience.org/library/papers/301172PubMed
44,200,776
Interaction of human thymus-derived and non-thymus-derived lymphocytes in vitro. Induction of proliferation and antibody synthesis in B lymphocytes by a soluble factor released from antigen-stimulated T lymphocytes.
J Exp Med1973https://conductscience.org/library/papers/4200776PubMed
54,122,710Sheep red cell binding to human lymphocytes treated with neuraminidase; enhancement of T cell binding and identification of a subpopulation of B cells.J Exp Med1973https://conductscience.org/library/papers/4122710PubMed
64,503,682Replacement of T-cell function by a T-cell product.Nat New Biol1972https://conductscience.org/library/papers/4503682PubMed
74,169,033Chromic chloride: a coupling reagent for passive hemagglutination reactions.J Immunol1967https://conductscience.org/library/papers/4169033PubMed
84,610,078Antigen-specific T-cell factor in cell cooperation: physical properties and mapping in the left-hand (K) half of H-2.J Exp Med1974https://conductscience.org/library/papers/4610078PubMed
953,267Expression of individual Ia specificities on T and B cells. I. Studies with mitogen-induced blast cells.J Exp Med1976https://conductscience.org/library/papers/53267PubMed
104,587,740A rapid method for the isolation of functional thymus-derived murine lymphocytes.Eur J Immunol1973https://conductscience.org/library/papers/4587740PubMed

Cited by26

The papers in our copy of PubMed whose reference list names this one, newest first. iCite, which reads more sources, counts 63 citations.

PMIDTitleJournalYearIn PapersSource
7,033,287
Immunoglobulin production induced in vitro by glucocorticoid hormones: T cell-dependent stimulation of immunoglobulin production without B cell proliferation in cultures of human peripheral blood lymphocytes.
J Clin Invest1981https://conductscience.org/library/papers/7033287PubMed
7,032,768Characterization of polymyositis infiltrates using monoclonal antibodies to human leucocyte antigens.Clin Exp Immunol1981https://conductscience.org/library/papers/7032768PubMed
7,007,212Partial characterization of murine and monkey helper factor to a streptococcal antigen.Immunology1980https://conductscience.org/library/papers/7007212PubMed
6,978,212Human anti-tetanus antibody response in vitro: autologous and allogeneic T cells provide help by different routes.Clin Exp Immunol1981https://conductscience.org/library/papers/6978212PubMed
6,795,110Antigen B-specific helper factor from timothy grass pollen: isolation and partial characterization.Immunology1981https://conductscience.org/library/papers/6795110PubMed
6,792,726In vitro antibody response of human lymphocytes.Springer Semin Immunopathol1980https://conductscience.org/library/papers/6792726PubMed
6,608,488Non-specific factor enhancement of human in vitro antigen-dependent antibody synthesis: role of B cell activation and T cell help.Immunology1984https://conductscience.org/library/papers/6608488PubMed
6,605,303The interaction of specific T-cell help and non-specific B-cell growth factors in the production of anti-tetanus antibody by human B cells grown in serum-free microcultures.Immunology1983https://conductscience.org/library/papers/6605303PubMed
6,603,301Human B cell growth factors overcome T cell-mediated inhibition of specific antibody production: a possible mechanism for the exacerbation of autoimmune disease.Clin Exp Immunol1983https://conductscience.org/library/papers/6603301PubMed
6,602,149Synthesis of antibodies to hepatitis B virus by cultured lymphocytes from chronic hepatitis B surface antigen carriers.J Clin Invest1983https://conductscience.org/library/papers/6602149PubMed

1 to 10 of 26

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Genes0

The genes the Gene search release ties to the paper: Swiss-Prot's references first, then PubTator's text mining.

None in this release.

Drugs0

The drugs whose trials, in the Pipelines release, list the paper.

None in this release.

Data0

The data bank entries PubMed's record names. Trial numbers are under Trials.

None in this release.

Data dates

The date of each source this release read.

PubMed
2026-11-06
PubMed
iCite
2026-11-05
iCite
PMC's ID file
2026-11-05
PMC's ID file
NIH RePORTER's grant and paper links
2026-11-01
NIH RePORTER's grant and paper links
Trials
2026-11-12
Gene search
2026-11-11
Pipelines
2026-09-18

Sources 11

  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • HGNCCC0
  • iCiteCC BY 4.0
  • NCBI GenePublic domain (US government)
  • NIH RePORTER's grant and paper linksPublic domain
  • Open TargetsCC0 1.0
  • PMC's ID filePublic domain (US government)
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • HGNCCC0: https://www.genenames.org/about/license/
  • iCiteCC BY 4.0
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH RePORTER's grant and paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PMC's ID fileNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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