Paper · 36734882

MiR-181a-5p promotes osteogenesis by targeting BMP3.

Long Z and 4 others. Aging (Albany NY), 2023. Cited by 30 papers, by iCite.

11 sourcespapers-2026-11-12-0.1.0

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ConductScience Library. MiR-181a-5p promotes osteogenesis by targeting BMP3. Papers, record 36734882. Release papers-2026-11-12-0.1.0, 12 Nov 2026. https://conductscience.org/library/papers/36734882

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Paper

PubMed's record of the paper, with iCite's citation figures. No abstract is shown.

Title: MiR-181a-5p promotes osteogenesis by targeting BMP3.; PubMed
Journal: Aging (Albany NY); PubMed
Year: 2023; PubMed
Publication types: Journal Article, Research Support, Non-U.S. Gov't; PubMed
PubMed: https://pubmed.ncbi.nlm.nih.gov/36734882/; PubMed
DOI: https://doi.org/10.18632/aging.204505; PubMed
PMC: https://pmc.ncbi.nlm.nih.gov/articles/PMC9970307/; PubMed
The journal: https://conductscience.org/library/journal-index/101508617; PubMed
Citations, by iCite: 30; iCite
Relative citation ratio, by iCite: 4.5; iCite
Revised in PubMed: 2023-03-01; PubMed

Authors5

The authors in the order PubMed's record lists them, with the ORCID iDs it states.

Order	Author	Forename
1	Long Z	Ze
2	Dou P	Pengcheng
3	Cai W	Weiliang
4	Mao M	Minzhi
5	Wu R	Ren

Source PubMed

Topics7

NLM's MeSH indexing of the paper, its major topics first.

MeSH term	Major
MicroRNAs	Major topic
Osteoporosis	Major topic
Mice
Animals
Osteogenesis
Bone Morphogenetic Protein 3
Cell Differentiation

Source PubMed

Grants0

Each grant PubMed's record writes, matched to the NIH project NIH's grant and paper links name for this paper, and each of those links the record does not write.

None in this release.

Trials0

The trials whose ClinicalTrials.gov record lists the paper, and the trial numbers the paper's PubMed record names.

None in this release.

Comments and corrections0

PubMed's comments and corrections, NLM's own indexing: retractions first, then expressions of concern, errata and updates, and comments last.

None in this release.

References42

The papers the reference list in PubMed's record names, those in our copy of PubMed, in the list's order.

Order	PMID	Title	Journal	Year	In Papers	Source
1	9,182,764	Cbfa1, a candidate gene for cleidocranial dysplasia syndrome, is essential for osteoblast differentiation and bone development.	Cell	1997	https://conductscience.org/library/papers/9182764	PubMed
2	31,165,768	Variable osteogenic performance of MC3T3-E1 subclones impacts their utility as models of osteoblast biology.	Sci Rep	2019	https://conductscience.org/library/papers/31165768	PubMed
3	23,262,291	miR-181a promotes osteoblastic differentiation through repression of TGF-β signaling molecules.	Int J Biochem Cell Biol	2013	https://conductscience.org/library/papers/23262291	PubMed
4	35,626,707	The Role of MiR-181 Family Members in Endothelial Cell Dysfunction and Tumor Angiogenesis.	Cells	2022	https://conductscience.org/library/papers/35626707	PubMed
5	34,299,372	Evaluation of MC3T3-E1 Cell Osteogenesis in Different Cell Culture Media.	Int J Mol Sci	2021	https://conductscience.org/library/papers/34299372	PubMed
6	34,064,134	Regulation and Role of Transcription Factors in Osteogenesis.	Int J Mol Sci	2021	https://conductscience.org/library/papers/34064134	PubMed
7	23,689,830	The relevance of mouse models for investigating age-related bone loss in humans.	J Gerontol A Biol Sci Med Sci	2013	https://conductscience.org/library/papers/23689830	PubMed
8	22,491,715	microRNA involvement in human cancer.	Carcinogenesis	2012	https://conductscience.org/library/papers/22491715	PubMed
9	27,005,616	MicroRNAs in Osteoclastogenesis and Function: Potential Therapeutic Targets for Osteoporosis.	Int J Mol Sci	2016	https://conductscience.org/library/papers/27005616	PubMed
10	27,082,893	Epigenetic regulation of bone cells.	Connect Tissue Res	2017	https://conductscience.org/library/papers/27082893	PubMed

1 to 10 of 42

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Cited by22

The papers in our copy of PubMed whose reference list names this one, newest first. iCite, which reads more sources, counts 30 citations.

PMID	Title	Journal	Year	In Papers	Source
42,219,493	miR-211-5p/FOXO3 axis accelerates osteogenic differentiation and fracture healing by mediating Wnt/β-catenin pathway.	J Orthop Surg Res	2026	https://conductscience.org/library/papers/42219493	PubMed
41,782,000	miR-1290 serves as a potential biomarker for osteoporotic fracture and regulates osteoblast function by targeting KDM5A.	J Orthop Surg Res	2026	https://conductscience.org/library/papers/41782000	PubMed
41,353,424	miR-338-3p targets WAPL to suppress proliferation and invasion in cervical cancer cells: experimental insights.	World J Surg Oncol	2025	https://conductscience.org/library/papers/41353424	PubMed
40,781,581	Whole genome resequencing reveals genetic diversity, population structure, and selection signatures in local duck breeds.	BMC Genomics	2025	https://conductscience.org/library/papers/40781581	PubMed
40,713,616	The role and regulatory mechanism of miR-122-5p in the process of pilon fracture healing.	J Orthop Surg Res	2025	https://conductscience.org/library/papers/40713616	PubMed
40,663,175	Metformin promotes osteogenic differentiation of human periodontal ligament stem cells via KLF2-mediated activation of miR-181a-5p under lipopolysaccharide stimulation.	Hum Cell	2025	https://conductscience.org/library/papers/40663175	PubMed
40,368,863	[Effect of stretch on taurine upregulated gene 1-mediated miR-545-3p/cannbinoida receptor 2 pathway regulating distraction osteogenesis in rats].	Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi	2025	https://conductscience.org/library/papers/40368863	PubMed
40,322,028	Curculigoside is a Promising Osteoprotective Agent for Osteoporosis: Review.	Drug Des Devel Ther	2025	https://conductscience.org/library/papers/40322028	PubMed
40,038,790	MiR-147b-3p promotes osteogenesis by targeting NDUFA4 and PI3K/AKT pathway.	J Orthop Surg Res	2025	https://conductscience.org/library/papers/40038790	PubMed
39,924,543	FBN2 promotes the proliferation, mineralization, and differentiation of osteoblasts to accelerate fracture healing.	Sci Rep	2025	https://conductscience.org/library/papers/39924543	PubMed

1 to 10 of 22

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Genes3

The genes the Gene search release ties to the paper: Swiss-Prot's references first, then PubTator's text mining.

Gene	NCBI Gene ID	Linked by	In Genes	Source
ALPP	250	PubTator's text mining	https://conductscience.org/library/genes/250	NCBI Gene
BMP3	651	PubTator's text mining	https://conductscience.org/library/genes/651	NCBI Gene
PBX1	5,087	PubTator's text mining	https://conductscience.org/library/genes/5087	NCBI Gene

Drugs0

The drugs whose trials, in the Pipelines release, list the paper.

None in this release.

Data0

The data bank entries PubMed's record names. Trial numbers are under Trials.

None in this release.

Data dates

The date of each source this release read.

PubMed: 2026-11-06; PubMed
iCite: 2026-11-05; iCite
PMC's ID file: 2026-11-05; PMC's ID file
NIH RePORTER's grant and paper links: 2026-11-01; NIH RePORTER's grant and paper links
Trials: 2026-11-12
Gene search: 2026-11-11
Pipelines: 2026-09-18

Sources 11

ChEMBL, through Open TargetsCC BY-SA 3.0
ClinicalTrials.govNo license stated
HGNCCC0
iCiteCC BY 4.0
NCBI GenePublic domain (US government)
NIH RePORTER's grant and paper linksPublic domain
Open TargetsCC0 1.0
PMC's ID filePublic domain (US government)
PubMedNLM's terms
PubTator 3Public domain
UniProtCC BY 4.0

Each source's terms

ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
ClinicalTrials.govnone stated
HGNCCC0: https://www.genenames.org/about/license/
iCiteCC BY 4.0
NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
NIH RePORTER's grant and paper linksPublic domain (NIH RePORTER)
Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
PMC's ID fileNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
PubMedNLM's terms
PubTator 3Public domain
UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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