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Paper38534331

Low Density Lipoprotein Cholesterol Decreases the Expression of Adenosine A2A Receptor and Lipid Rafts-Protein Flotillin-1: Insights on Cardiovascular Risk of Hypercholesterolemia.

Chaptal MC and 13 others. Cells, 2024. Cited by 4 papers, by iCite.

11 sourcespapers-2026-11-12-0.1.0

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ConductScience Library. Low Density Lipoprotein Cholesterol Decreases the Expression of Adenosine A2A Receptor and Lipid Rafts-Protein Flotillin-1: Insights on Cardiovascular Risk of Hypercholesterolemia. Papers, record 38534331. Release papers-2026-11-12-0.1.0, 12 Nov 2026. https://conductscience.org/library/papers/38534331

Paper

PubMed's record of the paper, with iCite's citation figures. No abstract is shown.

Title
Low Density Lipoprotein Cholesterol Decreases the Expression of Adenosine A2A Receptor and Lipid Rafts-Protein Flotillin-1: Insights on Cardiovascular Risk of Hypercholesterolemia.
PubMed
Journal
Cells
PubMed
Year
2024
PubMed
Publication types
Journal Article, Research Support, Non-U.S. Gov't
PubMed
Citations, by iCite
4
iCite
Relative citation ratio, by iCite
0.92, provisional
iCite
Revised in PubMed
2025-01-16
PubMed

Authors14

The authors in the order PubMed's record lists them, with the ORCID iDs it states.

OrderAuthorForenameKindORCID iD
1Chaptal MCMarie-Charlotte
2Maraninchi MMariehttps://orcid.org/0000-0002-6645-1811
3Musto GGiorgia
4Mancini JJulienhttps://orcid.org/0000-0001-9500-8598
5Chtioui HHedi
6Dupont-Roussel JJanine
7Marlinge MMarion
8Fromonot JJulienhttps://orcid.org/0000-0001-6726-9125
9Lalevee NNathaliehttps://orcid.org/0000-0003-1924-1667
10Mourre FFlorian
11Beliard SSophie
12Guieu RRégis
13Valero RRenéhttps://orcid.org/0000-0002-2176-3280
14Mottola GGiovannahttps://orcid.org/0000-0002-7541-0472

Source PubMed

Topics13

NLM's MeSH indexing of the paper, its major topics first.

MeSH termMajor
HypercholesterolemiaMajor topic
Cardiovascular DiseasesMajor topic
Membrane ProteinsMajor topic
Humans
Cholesterol, LDL
Receptor, Adenosine A2A
Leukocytes, Mononuclear
Adenosine
Risk Factors
Cholesterol
Carrier Proteins
Heart Disease Risk Factors
Membrane Microdomains

Source PubMed

References75

The papers the reference list in PubMed's record names, those in our copy of PubMed, in the list's order.

OrderPMIDTitleJournalYearIn PapersSource
122,591,295Association of coffee drinking with total and cause-specific mortality.N Engl J Med2012https://conductscience.org/library/papers/22591295PubMed
236,769,539Advances in the Pathophysiology of Thrombosis in Antiphospholipid Syndrome: Molecular Mechanisms and Signaling through Lipid Rafts.J Clin Med2023https://conductscience.org/library/papers/36769539PubMed
328,513,806Increased activity of vascular adenosine deaminase in atherosclerosis and therapeutic potential of its inhibition.Cardiovasc Res2016https://conductscience.org/library/papers/28513806PubMed
424,090,652Potential role of A2A adenosine receptor in traumatic optic neuropathy.J Neuroimmunol2013https://conductscience.org/library/papers/24090652PubMed
510,448,520The mammalian low-density lipoprotein receptor family.Annu Rev Nutr1999https://conductscience.org/library/papers/10448520PubMed
628,220,900Membrane cholesterol access into a G-protein-coupled receptor.Nat Commun2017https://conductscience.org/library/papers/28220900PubMed
732,225,034Flotillins: At the Intersection of Protein S-Palmitoylation and Lipid-Mediated Signaling.Int J Mol Sci2020https://conductscience.org/library/papers/32225034PubMed
815,713,660The stomatin/prohibitin/flotillin/HflK/C domain of flotillin-1 contains distinct sequences that direct plasma membrane localization and protein interactions in 3T3-L1 adipocytes.J Biol Chem2005https://conductscience.org/library/papers/15713660PubMed
931,504,4182019 ESC/EAS Guidelines for the management of dyslipidaemias: lipid modification to reduce cardiovascular risk.Eur Heart J2020https://conductscience.org/library/papers/31504418PubMed
1019,041,138Production of an agonist-like monoclonal antibody to the human A2A receptor of adenosine for clinical use.Mol Immunol2009https://conductscience.org/library/papers/19041138PubMed
1132,256,352Ferroptosis and Its Potential Role in Human Diseases.Front Pharmacol2020https://conductscience.org/library/papers/32256352PubMed
1233,117,828Overview of the Assessment of Endothelial Function in Humans.Front Med (Lausanne)2020https://conductscience.org/library/papers/33117828PubMed
1318,218,631Restricted collision coupling of the A2A receptor revisited: evidence for physical separation of two signaling cascades.J Biol Chem2008https://conductscience.org/library/papers/18218631PubMed
149,495,868The A2A adenosine receptor mediates coronary vasodilation.J Pharmacol Exp Ther1998https://conductscience.org/library/papers/9495868PubMed
1512,475,889Changes of peripheral A2A adenosine receptors in chronic heart failure and cardiac transplantation.FASEB J2003https://conductscience.org/library/papers/12475889PubMed
1631,848,472Mechanisms and regulation of cholesterol homeostasis.Nat Rev Mol Cell Biol2020https://conductscience.org/library/papers/31848472PubMed
1716,957,081Protecting motor neurons from toxic insult by antagonism of adenosine A2a and Trk receptors.J Neurosci2006https://conductscience.org/library/papers/16957081PubMed
1816,920,910Cutting edge: Critical role for A2A adenosine receptors in the T cell-mediated regulation of colitis.J Immunol2006https://conductscience.org/library/papers/16920910PubMed
1935,474,963Multiparametric platform for profiling lipid trafficking in human leukocytes.Cell Rep Methods2022https://conductscience.org/library/papers/35474963PubMed
2034,711,342Familial Hypercholesterolemia: JACC Focus Seminar 4/4.J Am Coll Cardiol2021https://conductscience.org/library/papers/34711342PubMed

See all 75 references

Cited by3

The papers in our copy of PubMed whose reference list names this one, newest first. iCite, which reads more sources, counts 4 citations.

PMIDTitleJournalYearIn PapersSource
41,720,808Adenosine from high-fat-diet-tolerant monkey-derived Limsolactobacillus reuteri MacFasB02 modulates cholesterol metabolism to alleviate hyperlipidemia and inflammation.NPJ Sci Food2026https://conductscience.org/library/papers/41720808PubMed
40,801,651Synthetic Small-Molecule Ligands Targeted to Adenosine Receptors: Is There Potential Towards Ischemic Heart Disease?Cells2025https://conductscience.org/library/papers/40801651PubMed
40,668,534Purinergic receptors in atherosclerosis: implications for pathophysiology and therapeutic strategies.J Physiol Biochem2025https://conductscience.org/library/papers/40668534PubMed

Genes3

The genes the Gene search release ties to the paper: Swiss-Prot's references first, then PubTator's text mining.

GeneNCBI Gene IDLinked byIn GenesSource
ADORA2A135PubTator's text mininghttps://conductscience.org/library/genes/135NCBI Gene
FLOT110,211PubTator's text mininghttps://conductscience.org/library/genes/10211NCBI Gene
TF7,018PubTator's text mininghttps://conductscience.org/library/genes/7018NCBI Gene

Data dates

The date of each source this release read.

PubMed
2026-11-06
PubMed
iCite
2026-11-05
iCite
PMC's ID file
2026-11-05
PMC's ID file
NIH RePORTER's grant and paper links
2026-11-01
NIH RePORTER's grant and paper links
Trials
2026-11-12
Gene search
2026-11-11
Pipelines
2026-09-18

None in this release

  • Grants
  • Trials
  • Comments and corrections
  • Drugs
  • Data

Sources 11

  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • HGNCCC0
  • iCiteCC BY 4.0
  • NCBI GenePublic domain (US government)
  • NIH RePORTER's grant and paper linksPublic domain
  • Open TargetsCC0 1.0
  • PMC's ID filePublic domain (US government)
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • HGNCCC0: https://www.genenames.org/about/license/
  • iCiteCC BY 4.0
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH RePORTER's grant and paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PMC's ID fileNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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