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Paper389043

Synthetic DNA and medicine.

Riggs AD and 1 other. Am J Hum Genet, 1979. Cited by 11 papers, by iCite.

11 sourcespapers-2026-11-12-0.1.0

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ConductScience Library. Synthetic DNA and medicine. Papers, record 389043. Release papers-2026-11-12-0.1.0, 12 Nov 2026. https://conductscience.org/library/papers/389043

Paper

PubMed's record of the paper, with iCite's citation figures. No abstract is shown.

Title
Synthetic DNA and medicine.
PubMed
Journal
Am J Hum Genet
PubMed
Year
1979
PubMed
Publication types
Journal Article
PubMed
Citations, by iCite
11
iCite
Relative citation ratio, by iCite
0.22
iCite
Revised in PubMed
2020-08-24
PubMed

Authors2

The authors in the order PubMed's record lists them, with the ORCID iDs it states.

OrderAuthorForenameKindORCID iD
1Riggs ADA D
2Itakura KK

Source PubMed

Topics7

NLM's MeSH indexing of the paper, its major topics first.

MeSH termMajor
Cloning, MolecularMajor topic
DNA, RecombinantMajor topic
Genes, SyntheticMajor topic
Escherichia coli
Humans
Insulin
Mutation

Source PubMed

References18

The papers the reference list in PubMed's record names, those in our copy of PubMed, in the list's order.

OrderPMIDTitleJournalYearIn PapersSource
1281,713Polymorphism of DNA sequence adjacent to human beta-globin structural gene: relationship to sickle mutation.Proc Natl Acad Sci U S A1978https://conductscience.org/library/papers/281713PubMed
2366,749Total synthesis of a gene.Science1979https://conductscience.org/library/papers/366749PubMed
3279,913Efficient correction of a mutation by use of chemically synthesized DNA.Proc Natl Acad Sci U S A1978https://conductscience.org/library/papers/279913PubMed
485,300Expression in Escherichia coli of chemically synthesized genes for human insulin.Proc Natl Acad Sci U S A1979https://conductscience.org/library/papers/85300PubMed
580,751Synthesis of an ovalbumin-like protein by Escherichia coli K12 harbouring a recombinant plasmid.Nature1978https://conductscience.org/library/papers/80751PubMed
6210,956Identification and isolation of the yeast cytochrome c gene.Cell1978https://conductscience.org/library/papers/210956PubMed
7209,457Local mutagenesis: a method for generating viral mutants with base substitutions in preselected regions of the viral genome.Proc Natl Acad Sci U S A1978https://conductscience.org/library/papers/209457PubMed
8104,296Chicken ovalbumin is synthesized and secreted by Escherichia coli.Proc Natl Acad Sci U S A1978https://conductscience.org/library/papers/104296PubMed
9412,251Expression in Escherichia coli of a chemically synthesized gene for the hormone somatostatin.Science1977https://conductscience.org/library/papers/412251PubMed
10366,607In vitro mutagenesis of a circular DNA molecule by using synthetic restriction sites.Proc Natl Acad Sci U S A1978https://conductscience.org/library/papers/366607PubMed
11364,320Synthesis of growth hormone by bacteria.Nature1978https://conductscience.org/library/papers/364320PubMed
12360,074Phenotypic expression in E. coli of a DNA sequence coding for mouse dihydrofolate reductase.Nature1978https://conductscience.org/library/papers/360074PubMed
13358,198A bacterial clone synthesizing proinsulin.Proc Natl Acad Sci U S A1978https://conductscience.org/library/papers/358198PubMed
14282,602Chemical synthesis of genes for human insulin.Proc Natl Acad Sci U S A1978https://conductscience.org/library/papers/282602PubMed
15681,366Mutagenesis at a specific position in a DNA sequence.J Biol Chem1978https://conductscience.org/library/papers/681366PubMed
16870,828Nucleotide sequence of bacteriophage phi X174 DNA.Nature1977https://conductscience.org/library/papers/870828PubMed
176,069,705Studies on the synthesis of insulin from natural and synthetic A and B chains. I. Splitting of insulin and isolation of the S-sulfonated derivatives of the A and B chains.Biochemistry1967https://conductscience.org/library/papers/6069705PubMed
18166,998Chemical synthesis and sequence studies of deoxyribooligonucleotides which constitute the duplex sequence of the lactose operator of Escherichia coli.J Biol Chem1975https://conductscience.org/library/papers/166998PubMed

Cited by2

The papers in our copy of PubMed whose reference list names this one, newest first. iCite, which reads more sources, counts 11 citations.

PMIDTitleJournalYearIn PapersSource
7,037,514New approaches to therapy and diagnosis of diabetes.Diabetologia1982https://conductscience.org/library/papers/7037514PubMed
292,308Powerful new tools in genetics.Am J Hum Genet1979https://conductscience.org/library/papers/292308PubMed

Data dates

The date of each source this release read.

PubMed
2026-11-06
PubMed
iCite
2026-11-05
iCite
PMC's ID file
2026-11-05
PMC's ID file
NIH RePORTER's grant and paper links
2026-11-01
NIH RePORTER's grant and paper links
Trials
2026-11-12
Gene search
2026-11-11
Pipelines
2026-09-18

None in this release

  • Grants
  • Trials
  • Comments and corrections
  • Genes
  • Drugs
  • Data

Sources 11

  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • HGNCCC0
  • iCiteCC BY 4.0
  • NCBI GenePublic domain (US government)
  • NIH RePORTER's grant and paper linksPublic domain
  • Open TargetsCC0 1.0
  • PMC's ID filePublic domain (US government)
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • HGNCCC0: https://www.genenames.org/about/license/
  • iCiteCC BY 4.0
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH RePORTER's grant and paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PMC's ID fileNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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