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Paper · 39227612

SPRED3 regulates the NF-κB signaling pathway in thyroid cancer and promotes the proliferation.

Chen Z and 4 others. Sci Rep, 2024. Cited by 7 papers, by iCite.

11 sourcespapers-2026-11-12-0.1.0

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ConductScience Library. SPRED3 regulates the NF-κB signaling pathway in thyroid cancer and promotes the proliferation. Papers, record 39227612. Release papers-2026-11-12-0.1.0, 12 Nov 2026. https://conductscience.org/library/papers/39227612

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Paper

PubMed's record of the paper, with iCite's citation figures. No abstract is shown.

Title
SPRED3 regulates the NF-κB signaling pathway in thyroid cancer and promotes the proliferation.
PubMed
Journal
Sci Rep
PubMed
Year
2024
PubMed
Publication types
Journal Article
PubMed
Citations, by iCite
7
iCite
Relative citation ratio, by iCite
0.94, provisional
iCite
Revised in PubMed
2026-01-27
PubMed

Authors5

The authors in the order PubMed's record lists them, with the ORCID iDs it states.

OrderAuthorForenameKindORCID iD
1Chen ZZhiping
2Wang CCongren
3Li MMingzhu
4Cai SShaoyang
5Liu XXiaoyu

Source PubMed

Topics16

NLM's MeSH indexing of the paper, its major topics first.

MeSH termMajor
Cell ProliferationMajor topic
NF-kappa BMajor topic
Signal TransductionMajor topic
Thyroid NeoplasmsMajor topic
Animals
Female
Humans
Male
Mice
Middle Aged
Cell Line, Tumor
Gene Expression Regulation, Neoplastic
Prognosis
Thyroid Cancer, Papillary
Tumor Microenvironment
Repressor Proteins

Source PubMed

Grants1

Each grant PubMed's record writes, matched to the NIH project NIH's grant and paper links name for this paper, and each of those links the record does not write.

Grant, as the record writes itAgencyCountryNIH projectStated by
2022J01120919Fujian Natural Science Foundation ProgramPubMed

Source PubMed

Trials0

The trials whose ClinicalTrials.gov record lists the paper, and the trial numbers the paper's PubMed record names.

None in this release.

Comments and corrections0

PubMed's comments and corrections, NLM's own indexing: retractions first, then expressions of concern, errata and updates, and comments last.

None in this release.

References38

The papers the reference list in PubMed's record names, those in our copy of PubMed, in the list's order.

OrderPMIDTitleJournalYearIn PapersSource
134,057,118Overexpression of NF-kB as a predictor of neoadjuvant chemotherapy response in breast cancer.Breast Dis2021https://conductscience.org/library/papers/34057118PubMed
235,220,887Fusobacterium nucleatum promotes colorectal cancer cells adhesion to endothelial cells and facilitates extravasation and metastasis by inducing ALPK1/NF-κB/ICAM1 axis.Gut Microbes2022https://conductscience.org/library/papers/35220887PubMed
319,156,774Aberrant BRAF splicing as an alternative mechanism for oncogenic B-Raf activation in thyroid carcinoma.J Pathol2009https://conductscience.org/library/papers/19156774PubMed
418,177,721The biology of cancer: metabolic reprogramming fuels cell growth and proliferation.Cell Metab2008https://conductscience.org/library/papers/18177721PubMed
531,097,454Inhibiting BRAF Oncogene-Mediated Radioresistance Effectively Radiosensitizes BRAFV600E-Mutant Thyroid Cancer Cells by Constraining DNA Double-Strand Break Repair.Clin Cancer Res2019https://conductscience.org/library/papers/31097454PubMed
630,874,331The Sprouty/Spred family as tumor suppressors: Coming of age.Cancer Sci2019https://conductscience.org/library/papers/30874331PubMed
733,276,434NF-κB and Disease.Int J Mol Sci2020https://conductscience.org/library/papers/33276434PubMed
832,409,139NF-κB in the New Era of Cancer Therapy.Trends Cancer2020https://conductscience.org/library/papers/32409139PubMed
931,816,325HMGB1 upregulates NF-kB by inhibiting IKB-α and associates with diabetic retinopathy.Life Sci2020https://conductscience.org/library/papers/31816325PubMed
1032,046,099Targeting MAPK Signaling in Cancer: Mechanisms of Drug Resistance and Sensitivity.Int J Mol Sci2020https://conductscience.org/library/papers/32046099PubMed

1 to 10 of 38

See all 38 references

Cited by7

The papers in our copy of PubMed whose reference list names this one, newest first. iCite, which reads more sources, counts 7 citations.

PMIDTitleJournalYearIn PapersSource
42,698,456Investigating the impact of Sprouty-related EVH1 domain-containing protein 3 on gastric cancer prognosis and tumor microenvironments.Front Oncol2026https://conductscience.org/library/papers/42698456PubMed
41,984,095Aryl hydrocarbon receptor orchestrates transcriptomic, non-coding and splicing programs that drive human lung epithelial responses to vaporized cannabis in vitro.Arch Toxicol2026https://conductscience.org/library/papers/41984095PubMed
41,369,405Extracellular Vesicles from iPSC-Derived Glial Progenitor Cells Prevent Glutamate-Induced Excitotoxicity by Stabilising Calcium Oscillations and Mitochondrial Depolarisation.Cells2025https://conductscience.org/library/papers/41369405PubMed
41,158,264Development and validation of a necroptosis-related gene signature for predicting prognosis and immune infiltration in papillary thyroid cancer.Transl Cancer Res2025https://conductscience.org/library/papers/41158264PubMed
41,068,688Distinct genomic subgroups and mutational patterns in undifferentiated/dedifferentiated endometrial carcinoma.BMC Cancer2025https://conductscience.org/library/papers/41068688PubMed
40,806,788Loss of SPRED3 Causes Primary Hypothyroidism and Alters Thyroidal Expression of Autophagy Regulators LC3, p62, and ATG5 in Mice.Int J Mol Sci2025https://conductscience.org/library/papers/40806788PubMed
40,596,746Global Thyroid Cancer Patterns and Predictive Analytics: Integrating Machine Learning for Advanced Diagnostic Modelling.J Cell Mol Med2025https://conductscience.org/library/papers/40596746PubMed

Genes2

The genes the Gene search release ties to the paper: Swiss-Prot's references first, then PubTator's text mining.

GeneNCBI Gene IDLinked byIn GenesSource
NFKB14,790PubTator's text mininghttps://conductscience.org/library/genes/4790NCBI Gene
SPRED3399,473PubTator's text mininghttps://conductscience.org/library/genes/399473NCBI Gene

Drugs0

The drugs whose trials, in the Pipelines release, list the paper.

None in this release.

Data0

The data bank entries PubMed's record names. Trial numbers are under Trials.

None in this release.

Data dates

The date of each source this release read.

PubMed
2026-11-06
PubMed
iCite
2026-11-05
iCite
PMC's ID file
2026-11-05
PMC's ID file
NIH RePORTER's grant and paper links
2026-11-01
NIH RePORTER's grant and paper links
Trials
2026-11-12
Gene search
2026-11-11
Pipelines
2026-09-18

Sources 11

  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • HGNCCC0
  • iCiteCC BY 4.0
  • NCBI GenePublic domain (US government)
  • NIH RePORTER's grant and paper linksPublic domain
  • Open TargetsCC0 1.0
  • PMC's ID filePublic domain (US government)
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • HGNCCC0: https://www.genenames.org/about/license/
  • iCiteCC BY 4.0
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH RePORTER's grant and paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PMC's ID fileNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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