Paper · 3932053
Overview of clinical safety with misoprostol.
Herting RL and 1 other. Dig Dis Sci, 1985. Cited by 46 papers, by iCite.
11 sourcespapers-2026-11-12-0.1.0
Cite this record
ConductScience Library. Overview of clinical safety with misoprostol. Papers, record 3932053. Release papers-2026-11-12-0.1.0, 12 Nov 2026. https://conductscience.org/library/papers/3932053
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Paper
PubMed's record of the paper, with iCite's citation figures. No abstract is shown.
Topics17
NLM's MeSH indexing of the paper, its major topics first.
| MeSH term | Major |
|---|---|
| Alprostadil | Major topic |
| Anti-Ulcer Agents | Major topic |
| Biopsy | |
| Cimetidine | |
| Clinical Trials as Topic | |
| Diarrhea | |
| Double-Blind Method | |
| Gastric Mucosa | |
| Gastrointestinal Diseases | |
| Humans | |
| Iron | |
| Liver Function Tests | |
| Misoprostol | |
| Peptic Ulcer | |
| Placebos | |
| Pyloric Antrum | |
| Recurrence |
Source PubMed
Grants0
Each grant PubMed's record writes, matched to the NIH project NIH's grant and paper links name for this paper, and each of those links the record does not write.
None in this release.
Trials2
The trials whose ClinicalTrials.gov record lists the paper, and the trial numbers the paper's PubMed record names.
| Trial | Title | The trial lists it as | Named in the paper's record | Source |
|---|---|---|---|---|
| NCT02141555 | Comparing Buccal and Vaginal Misoprostol in Management of Early Pregnancy Loss | Background | ClinicalTrials.gov | |
| NCT02259309 | Immune Modulation by Misoprostol | Background | ClinicalTrials.gov |
Comments and corrections0
PubMed's comments and corrections, NLM's own indexing: retractions first, then expressions of concern, errata and updates, and comments last.
None in this release.
References8
The papers the reference list in PubMed's record names, those in our copy of PubMed, in the list's order.
| Order | PMID | Title | Journal | Year | In Papers | Source |
|---|---|---|---|---|---|---|
| 1 | 7,167,410 | Simple alkaline treatment induces intestinal metaplasia in the stomach of rats. | Pathol Res Pract | 1982 | https://conductscience.org/library/papers/7167410 | PubMed |
| 2 | 7,076,225 | Mucosal biopsy of the esophagus, stomach, and proximal duodenum. | Hum Pathol | 1982 | https://conductscience.org/library/papers/7076225 | PubMed |
| 3 | 3,932,048 | Misoprostol, a synthetic PGE1 analog, in the treatment of duodenal ulcers. A multicenter double-blind study. | Dig Dis Sci | 1985 | https://conductscience.org/library/papers/3932048 | PubMed |
| 4 | 7,430,384 | Precancerous conditions and epithelial dysplasia in the stomach. | J Clin Pathol | 1980 | https://conductscience.org/library/papers/7430384 | PubMed |
| 5 | 3,932,050 | Healing of benign gastric ulcer. A placebo-controlled comparison of two dosage regimens of misoprostol, a synthetic analog of prostaglandin E1. | Dig Dis Sci | 1985 | https://conductscience.org/library/papers/3932050 | PubMed |
| 6 | 3,932,049 | Misoprostol in the treatment of duodenal ulcer. A multicenter double-blind placebo-controlled study. | Dig Dis Sci | 1985 | https://conductscience.org/library/papers/3932049 | PubMed |
| 7 | 3,932,051 | A multicenter international controlled comparison of two dosage regimes of misoprostol and cimetidine in the treatment of duodenal ulcer in out-patients. | Dig Dis Sci | 1985 | https://conductscience.org/library/papers/3932051 | PubMed |
| 8 | 3,932,052 | Interim results of a multicenter international comparison of misoprostol and cimetidine in the treatment of out-patients with benign gastric ulcers. | Dig Dis Sci | 1985 | https://conductscience.org/library/papers/3932052 | PubMed |
Cited by9
The papers in our copy of PubMed whose reference list names this one, newest first. iCite, which reads more sources, counts 46 citations.
| PMID | Title | Journal | Year | In Papers | Source |
|---|---|---|---|---|---|
| 30,897,748 | Effects of Drugs and Excipients on Hydration Status. | Nutrients | 2019 | https://conductscience.org/library/papers/30897748 | PubMed |
| 10,647,976 | Drug-induced diarrhoea. | Drug Saf | 2000 | https://conductscience.org/library/papers/10647976 | PubMed |
| 10,146,962 | Misoprostol: pharmacoeconomics of its use as prophylaxis against gastroduodenal damage induced by nonsteroidal anti-inflammatory drugs. | Pharmacoeconomics | 1993 | https://conductscience.org/library/papers/10146962 | PubMed |
| 8,573,992 | Diclofenac/misoprostol. A review of its pharmacology and therapeutic efficacy in painful inflammatory conditions. | Drugs Aging | 1995 | https://conductscience.org/library/papers/8573992 | PubMed |
| 8,425,443 | Effects of PGE2, misoprostol, and enprostil on guinea pig enterocyte adenylate cyclase. Clinical implications. | Dig Dis Sci | 1993 | https://conductscience.org/library/papers/8425443 | PubMed |
| 7,859,585 | Safety of acid-suppressing drugs. | Dig Dis Sci | 1995 | https://conductscience.org/library/papers/7859585 | PubMed |
| 3,792,228 | Prostaglandins in peptic ulcer disease. An overview of current status and future directions. | Drugs | 1986 | https://conductscience.org/library/papers/3792228 | PubMed |
| 3,102,205 | Misoprostol. A preliminary review of its pharmacodynamic and pharmacokinetic properties, and therapeutic efficacy in the treatment of peptic ulcer disease. | Drugs | 1987 | https://conductscience.org/library/papers/3102205 | PubMed |
| 3,080,288 | Overview of misoprostol clinical experience. | Dig Dis Sci | 1986 | https://conductscience.org/library/papers/3080288 | PubMed |
Genes0
The genes the Gene search release ties to the paper: Swiss-Prot's references first, then PubTator's text mining.
None in this release.
Drugs0
The drugs whose trials, in the Pipelines release, list the paper.
None in this release.
Data0
The data bank entries PubMed's record names. Trial numbers are under Trials.
None in this release.
Data dates
The date of each source this release read.
- Trials
- 2026-11-12
- Gene search
- 2026-11-11
- Pipelines
- 2026-09-18
Sources 11
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- HGNCCC0
- iCiteCC BY 4.0
- NCBI GenePublic domain (US government)
- NIH RePORTER's grant and paper linksPublic domain
- Open TargetsCC0 1.0
- PMC's ID filePublic domain (US government)
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- HGNCCC0: https://www.genenames.org/about/license/
- iCiteCC BY 4.0
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH RePORTER's grant and paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PMC's ID fileNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
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