Paper39628652

Enhanced thrombin and plasmin generation profiles in alpha-2-antiplasmin-deficient patients: Data from the Rare Bleeding disorders in the Netherlands study.

Haisma B and 11 others. Res Pract Thromb Haemost, 2024. Cited by 0 papers, by iCite.

11 sourcespapers-2026-11-12-0.1.0

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ConductScience Library. Enhanced thrombin and plasmin generation profiles in alpha-2-antiplasmin-deficient patients: Data from the Rare Bleeding disorders in the Netherlands study. Papers, record 39628652. Release papers-2026-11-12-0.1.0, 12 Nov 2026. https://conductscience.org/library/papers/39628652

Paper

PubMed's record of the paper, with iCite's citation figures. No abstract is shown.

Title: Enhanced thrombin and plasmin generation profiles in alpha-2-antiplasmin-deficient patients: Data from the Rare Bleeding disorders in the Netherlands study.; PubMed
Journal: Res Pract Thromb Haemost; PubMed
Year: 2024; PubMed
Publication types: Journal Article; PubMed
PubMed: https://pubmed.ncbi.nlm.nih.gov/39628652/; PubMed
DOI: https://doi.org/10.1016/j.rpth.2024.102604; PubMed
PMC: https://pmc.ncbi.nlm.nih.gov/articles/PMC11613267/; PubMed
The journal: https://conductscience.org/library/journal-index/101703775; PubMed
Citations, by iCite: 0; iCite
Relative citation ratio, by iCite: 0.0, provisional; iCite
Revised in PubMed: 2024-12-05; PubMed

Authors12

The authors in the order PubMed's record lists them, with the ORCID iDs it states.

Order	Author	Forename
1	Haisma B	Bauke
2	Rijpma SR	Sanna R
3	Cnossen MH	Marjon H
4	den Exter PL	Paul L
5	Kruis IC	Ilmar C
6	Meijer K	Karina
7	Nieuwenhuizen L	Laurens
8	van Es N	Nick
9	Schutgens REG	Roger E G
10	Blijlevens NMA	Nicole M A
11	van Heerde WL	Waander L
12	Schols SEM	Saskia E M

Source PubMed

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Topics0

NLM's MeSH indexing of the paper, its major topics first.

None in this release.

References41

The papers the reference list in PubMed's record names, those in our copy of PubMed, in the list's order.

Order	PMID	Title	Journal	Year	In Papers	Source
1	2,939,896	Platelets modulate the proteolysis of factor VIII:C protein by plasmin.	Blood	1986	https://conductscience.org/library/papers/2939896	PubMed
2	26,153,047	The role of activated coagulation factor XII in overall clot stability and fibrinolysis.	Thromb Res	2015	https://conductscience.org/library/papers/26153047	PubMed
3	33,064,819	Bleeding severity in patients with rare bleeding disorders: real-life data from the RBiN study.	Blood Adv	2020	https://conductscience.org/library/papers/33064819	PubMed
4	35,687,811	Plasma-based assays distinguish hyperfibrinolysis and shutdown subgroups in trauma-induced coagulopathy.	J Trauma Acute Care Surg	2022	https://conductscience.org/library/papers/35687811	PubMed
5	28,253,193	Structural and functional insight into pan-endopeptidase inhibition by α2-macroglobulins.	Biol Chem	2017	https://conductscience.org/library/papers/28253193	PubMed
6	11,472,338	Congenital alpha(2)-plasmin inhibitor deficiencies: a review.	Br J Haematol	2001	https://conductscience.org/library/papers/11472338	PubMed
7	21,765,837	Alpha II Antiplasmin Deficiency Complicating Pregnancy: A Case Report.	Obstet Gynecol Int	2011	https://conductscience.org/library/papers/21765837	PubMed
8	8,647,939	The kidney is a major site of alpha(2)-antiplasmin production.	J Clin Invest	1996	https://conductscience.org/library/papers/8647939	PubMed
9	1,537,129	Plasma fibrinopeptide A levels in patients with acute myocardial infarction treated with alteplase. Correlation with concomitant heparin, coronary artery patency, and recurrent ischemia. The European Cooperative Study Group.	Circulation	1992	https://conductscience.org/library/papers/1537129	PubMed
10	1,689,358	Measurement of the 'fast' or complexed form of alpha 2 macroglobulin in biological fluids using a sandwich enzyme immunoassay.	J Immunol Methods	1990	https://conductscience.org/library/papers/1689358	PubMed
11	4,089,832	Severe hemorrhagic tendency in heterozygous alpha 2-antiplasmin deficiency.	Thromb Res	1985	https://conductscience.org/library/papers/4089832	PubMed
12	15,670,058	Bleeding and thrombotic problems in a patient with alpha2 plasmin inhibitor deficiency.	J Thromb Haemost	2005	https://conductscience.org/library/papers/15670058	PubMed
13	7,805,216	Plasmin-mediated activation of contact system in response to pharmacological thrombolysis.	Circulation	1995	https://conductscience.org/library/papers/7805216	PubMed
14	10,583,218	A novel missense mutation in the human plasmin inhibitor (alpha2-antiplasmin) gene associated with a bleeding tendency.	Br J Haematol	1999	https://conductscience.org/library/papers/10583218	PubMed
15	9,880,645	A case of intramedullary haematoma associated with congenital alpha2-plasmin inhibitor deficiency.	Pediatr Radiol	1998	https://conductscience.org/library/papers/9880645	PubMed
16	76,519	The alpha2-plasmin inhibitor levels in liver diseases.	Clin Chim Acta	1978	https://conductscience.org/library/papers/76519	PubMed
17	18,803,553	Menorrhagia and reproductive health in rare bleeding disorders: a study from the Indian subcontinent.	Haemophilia	2009	https://conductscience.org/library/papers/18803553	PubMed
18	1,806,461	Intramedullary multiple hematomas in siblings with congenital alpha-2-plasmin inhibitor deficiency: orthopedic surgery with protection by tranexamic acid.	Haemostasis	1991	https://conductscience.org/library/papers/1806461	PubMed
19	17,388,801	TAFIa, PAI-1 and alpha-antiplasmin: complementary roles in regulating lysis of thrombi and plasma clots.	J Thromb Haemost	2007	https://conductscience.org/library/papers/17388801	PubMed
20	31,469,483	Thrombin and plasmin generation in patients with plasminogen or plasminogen activator inhibitor type 1 deficiency.	Haemophilia	2019	https://conductscience.org/library/papers/31469483	PubMed

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Cited by1

The papers in our copy of PubMed whose reference list names this one, newest first. iCite, which reads more sources, counts 0 citations.

PMID	Title	Journal	Year	In Papers
42,780,071	Genetic and hemostatic characterization of PAI-1 deficiency and isolated hyperfibrinolysis: data from the RBiN study.	Res Pract Thromb Haemost	2026	https://conductscience.org/library/papers/42780071

Source PubMed

Genes3

The genes the Gene search release ties to the paper: Swiss-Prot's references first, then PubTator's text mining.

Gene	NCBI Gene ID	Linked by	In Genes	Source
F2	2,147	PubTator's text mining	https://conductscience.org/library/genes/2147	NCBI Gene
PLG	5,340	PubTator's text mining	https://conductscience.org/library/genes/5340	NCBI Gene
SERPINF2	5,345	PubTator's text mining	https://conductscience.org/library/genes/5345	NCBI Gene

Data dates

The date of each source this release read.

PubMed: 2026-11-06; PubMed
iCite: 2026-11-05; iCite
PMC's ID file: 2026-11-05; PMC's ID file
NIH RePORTER's grant and paper links: 2026-11-01; NIH RePORTER's grant and paper links
Trials: 2026-11-12
Gene search: 2026-11-11
Pipelines: 2026-09-18

None in this release

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ClinicalTrials.govNo license stated
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iCiteCC BY 4.0
NCBI GenePublic domain (US government)
NIH RePORTER's grant and paper linksPublic domain
Open TargetsCC0 1.0
PMC's ID filePublic domain (US government)
PubMedNLM's terms
PubTator 3Public domain
UniProtCC BY 4.0

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ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
ClinicalTrials.govnone stated
HGNCCC0: https://www.genenames.org/about/license/
iCiteCC BY 4.0
NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
NIH RePORTER's grant and paper linksPublic domain (NIH RePORTER)
Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
PMC's ID fileNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
PubMedNLM's terms
PubTator 3Public domain
UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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