Paper · 39739772
Loss of Mfn1 but not Mfn2 enhances adipogenesis.
Mann JP and 15 others. PLoS One, 2024. Cited by 4 papers, by iCite.
11 sourcespapers-2026-11-12-0.1.0
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ConductScience Library. Loss of Mfn1 but not Mfn2 enhances adipogenesis. Papers, record 39739772. Release papers-2026-11-12-0.1.0, 12 Nov 2026. https://conductscience.org/library/papers/39739772
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Paper
PubMed's record of the paper, with iCite's citation figures. No abstract is shown.
Topics12
NLM's MeSH indexing of the paper, its major topics first.
| MeSH term | Major |
|---|---|
| GTP Phosphohydrolases | Major topic |
| Adipogenesis | Major topic |
| 3T3-L1 Cells | Major topic |
| Adipocytes | Major topic |
| Fibroblasts | Major topic |
| Mitochondria | Major topic |
| Animals | |
| Mice | |
| Cell Differentiation | |
| PPAR gamma | |
| Mice, Knockout | |
| Fatty Acid-Binding Proteins |
Source PubMed
Grants2
Each grant PubMed's record writes, matched to the NIH project NIH's grant and paper links name for this paper, and each of those links the record does not write.
| Grant, as the record writes it | Agency | Country | NIH project | Stated by |
|---|---|---|---|---|
| Wellcome Trust | United Kingdom | PubMed | ||
| MC_UU_00015/7 | Medical Research Council | United Kingdom | PubMed |
Source PubMed
Trials0
The trials whose ClinicalTrials.gov record lists the paper, and the trial numbers the paper's PubMed record names.
None in this release.
Comments and corrections0
PubMed's comments and corrections, NLM's own indexing: retractions first, then expressions of concern, errata and updates, and comments last.
None in this release.
References77
The papers the reference list in PubMed's record names, those in our copy of PubMed, in the list's order.
| Order | PMID | Title | Journal | Year | In Papers | Source |
|---|---|---|---|---|---|---|
| 1 | 28,348,166 | Mfn2 is critical for brown adipose tissue thermogenic function. | EMBO J | 2017 | https://conductscience.org/library/papers/28348166 | PubMed |
| 2 | 26,230,519 | Mitofusin 2 Deficiency Affects Energy Metabolism and Mitochondrial Biogenesis in MEF Cells. | PLoS One | 2015 | https://conductscience.org/library/papers/26230519 | PubMed |
| 3 | 12,527,753 | Mitofusins Mfn1 and Mfn2 coordinately regulate mitochondrial fusion and are essential for embryonic development. | J Cell Biol | 2003 | https://conductscience.org/library/papers/12527753 | PubMed |
| 4 | 11,514,614 | Dynamin-related protein Drp1 is required for mitochondrial division in mammalian cells. | Mol Biol Cell | 2001 | https://conductscience.org/library/papers/11514614 | PubMed |
| 5 | 21,393,237 | Superoxide is produced by the reduced flavin in mitochondrial complex I: a single, unified mechanism that applies during both forward and reverse electron transfer. | J Biol Chem | 2011 | https://conductscience.org/library/papers/21393237 | PubMed |
| 6 | 21,267,801 | Dynamic regulation of mitochondrial network and oxidative functions during 3T3-L1 fat cell differentiation. | J Physiol Biochem | 2011 | https://conductscience.org/library/papers/21267801 | PubMed |
| 7 | 17,428,816 | Opa1 deficiency in a mouse model of autosomal dominant optic atrophy impairs mitochondrial morphology, optic nerve structure and visual function. | Hum Mol Genet | 2007 | https://conductscience.org/library/papers/17428816 | PubMed |
| 8 | 19,052,620 | Mitofusin 2 tethers endoplasmic reticulum to mitochondria. | Nature | 2008 | https://conductscience.org/library/papers/19052620 | PubMed |
| 9 | 15,899,901 | Disruption of fusion results in mitochondrial heterogeneity and dysfunction. | J Biol Chem | 2005 | https://conductscience.org/library/papers/15899901 | PubMed |
| 10 | 24,891,617 | Direct transcriptional repression of Zfp423 by Zfp521 mediates a bone morphogenic protein-dependent osteoblast versus adipocyte lineage commitment switch. | Mol Cell Biol | 2014 | https://conductscience.org/library/papers/24891617 | PubMed |
1 to 10 of 77
See all 77 referencesCited by4
The papers in our copy of PubMed whose reference list names this one, newest first. iCite, which reads more sources, counts 4 citations.
| PMID | Title | Journal | Year | In Papers | Source |
|---|---|---|---|---|---|
| 41,202,880 | TRPM8 inhibition reduces the size but increases the number of lipid droplets in mature adipocytes in vitro. | J Lipid Res | 2025 | https://conductscience.org/library/papers/41202880 | PubMed |
| 40,312,745 | Puerarin relives inflammation, bone destruction and facilitates osteogenic differentiation in periodontitis by enhancing mitochondrial autophagy via activating mitochondrial Mitofusin 2. | Stem Cell Res Ther | 2025 | https://conductscience.org/library/papers/40312745 | PubMed |
| 37,685,840 | Mitochondrial Dynamics in Neurodegenerative Diseases: Unraveling the Role of Fusion and Fission Processes. | Int J Mol Sci | 2023 | https://conductscience.org/library/papers/37685840 | PubMed |
| 37,573,386 | E4orf1 improves adipose tissue-specific metabolic risk factors and indicators of cognition function in a mouse model of Alzheimer's disease. | Nutr Diabetes | 2023 | https://conductscience.org/library/papers/37573386 | PubMed |
Genes0
The genes the Gene search release ties to the paper: Swiss-Prot's references first, then PubTator's text mining.
None in this release.
Drugs0
The drugs whose trials, in the Pipelines release, list the paper.
None in this release.
Data1
The data bank entries PubMed's record names. Trial numbers are under Trials.
| Data bank | Accession |
|---|---|
| GEO | GSE232502 |
Source GEO
Data dates
The date of each source this release read.
- Trials
- 2026-11-12
- Gene search
- 2026-11-11
- Pipelines
- 2026-09-18
Sources 11
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- HGNCCC0
- iCiteCC BY 4.0
- NCBI GenePublic domain (US government)
- NIH RePORTER's grant and paper linksPublic domain
- Open TargetsCC0 1.0
- PMC's ID filePublic domain (US government)
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- HGNCCC0: https://www.genenames.org/about/license/
- iCiteCC BY 4.0
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH RePORTER's grant and paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PMC's ID fileNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
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