ConductScience.org, home
Papers
API referenceFor AI assistants

Paper · 40565321

Myostatin Modulation in Spinal Muscular Atrophy: A Systematic Review of Preclinical and Clinical Evidence.

Gnazzo M and 8 others. Int J Mol Sci, 2025. Cited by 1 paper, by iCite.

11 sourcespapers-2026-11-12-0.1.0

Download JSON
Cite this record

ConductScience Library. Myostatin Modulation in Spinal Muscular Atrophy: A Systematic Review of Preclinical and Clinical Evidence. Papers, record 40565321. Release papers-2026-11-12-0.1.0, 12 Nov 2026. https://conductscience.org/library/papers/40565321

On this page

Paper

PubMed's record of the paper, with iCite's citation figures. No abstract is shown.

Title
Myostatin Modulation in Spinal Muscular Atrophy: A Systematic Review of Preclinical and Clinical Evidence.
PubMed
Journal
Int J Mol Sci
PubMed
Year
2025
PubMed
Publication types
Journal Article, Systematic Review
PubMed
Citations, by iCite
1
iCite
Revised in PubMed
2025-12-08
PubMed

Authors9

The authors in the order PubMed's record lists them, with the ORCID iDs it states.

OrderAuthorForenameKindORCID iD
1Gnazzo MMartina
2Pisanò GGiuliahttps://orcid.org/0009-0005-2730-2791
3Baldini VValentinahttps://orcid.org/0000-0001-5795-5834
4Giacomelli GGiovanna
5Scullin SSilvia
6Piccolo BBenedetta
7Turco ECEmanuela Claudiahttps://orcid.org/0000-0002-4896-1164
8Esposito SSusannahttps://orcid.org/0000-0003-4103-2837
9Pera MCMaria Carmelahttps://orcid.org/0000-0001-6777-1721

Source PubMed

Topics10

NLM's MeSH indexing of the paper, its major topics first.

MeSH termMajor
MyostatinMajor topic
Muscular Atrophy, SpinalMajor topic
Humans
Animals
Muscle, Skeletal
Disease Models, Animal
Signal Transduction
Mice
Motor Neurons
Clinical Trials as Topic

Source PubMed

Grants0

Each grant PubMed's record writes, matched to the NIH project NIH's grant and paper links name for this paper, and each of those links the record does not write.

None in this release.

Trials0

The trials whose ClinicalTrials.gov record lists the paper, and the trial numbers the paper's PubMed record names.

None in this release.

Comments and corrections0

PubMed's comments and corrections, NLM's own indexing: retractions first, then expressions of concern, errata and updates, and comments last.

None in this release.

References38

The papers the reference list in PubMed's record names, those in our copy of PubMed, in the list's order.

OrderPMIDTitleJournalYearIn PapersSource
115,567,067Regulation of GDF-8 signaling by the p38 MAPK.Cell Signal2005https://conductscience.org/library/papers/15567067PubMed
239,105,058Long-term efficacy, safety, and patient-reported outcomes of apitegromab in patients with spinal muscular atrophy: results from the 36-month TOPAZ study.Front Neurol2024https://conductscience.org/library/papers/39105058PubMed
333,963,971A Randomized Phase 1 Safety, Pharmacokinetic and Pharmacodynamic Study of the Novel Myostatin Inhibitor Apitegromab (SRK-015): A Potential Treatment for Spinal Muscular Atrophy.Adv Ther2021https://conductscience.org/library/papers/33963971PubMed
417,938,389Strengthening the Reporting of Observational Studies in Epidemiology (STROBE): explanation and elaboration.Ann Intern Med2007https://conductscience.org/library/papers/17938389PubMed
511,459,935Regulation of myostatin activity and muscle growth.Proc Natl Acad Sci U S A2001https://conductscience.org/library/papers/11459935PubMed
640,368,588Myostatin Levels in SMA Following Disease-Modifying Treatments: A Multi-Center Study.Ann Clin Transl Neurol2025https://conductscience.org/library/papers/40368588PubMed
739,408,601Taldefgrobep Alfa and the Phase 3 RESILIENT Trial in Spinal Muscular Atrophy.Int J Mol Sci2024https://conductscience.org/library/papers/39408601PubMed
834,446,261The PRISMA 2020 statement: an updated guideline for reporting systematic reviews.Rev Esp Cardiol (Engl Ed)2021https://conductscience.org/library/papers/34446261PubMed
939,201,450Impact of Disease Severity and Disease-Modifying Therapies on Myostatin Levels in SMA Patients.Int J Mol Sci2024https://conductscience.org/library/papers/39201450PubMed
1016,873,457Effect of swimming on myostatin expression in white and red gastrocnemius muscle and in cardiac muscle of rats.Exp Physiol2006https://conductscience.org/library/papers/16873457PubMed

1 to 10 of 38

See all 38 references

Cited by0

The papers in our copy of PubMed whose reference list names this one, newest first. iCite, which reads more sources, counts 1 citation.

None in this release.

Genes2

The genes the Gene search release ties to the paper: Swiss-Prot's references first, then PubTator's text mining.

GeneNCBI Gene IDLinked byIn GenesSource
MSTN2,660PubTator's text mininghttps://conductscience.org/library/genes/2660NCBI Gene
SMN16,606PubTator's text mininghttps://conductscience.org/library/genes/6606NCBI Gene

Drugs0

The drugs whose trials, in the Pipelines release, list the paper.

None in this release.

Data0

The data bank entries PubMed's record names. Trial numbers are under Trials.

None in this release.

Data dates

The date of each source this release read.

PubMed
2026-11-06
PubMed
iCite
2026-11-05
iCite
PMC's ID file
2026-11-05
PMC's ID file
NIH RePORTER's grant and paper links
2026-11-01
NIH RePORTER's grant and paper links
Trials
2026-11-12
Gene search
2026-11-11
Pipelines
2026-09-18

Sources 11

  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • HGNCCC0
  • iCiteCC BY 4.0
  • NCBI GenePublic domain (US government)
  • NIH RePORTER's grant and paper linksPublic domain
  • Open TargetsCC0 1.0
  • PMC's ID filePublic domain (US government)
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • HGNCCC0: https://www.genenames.org/about/license/
  • iCiteCC BY 4.0
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH RePORTER's grant and paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PMC's ID fileNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this paper from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/papers/v1/40565321

GET https://conductscience.org/api/papers/v1/40565321/references?page=2

API referenceFor AI assistants