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Paper · 40988015

Lipid droplet dynamics in type 2 diabetes and its complications: pathophysiological insights and therapeutic options.

Long C and 7 others. Lipids Health Dis, 2025. Cited by 6 papers, by iCite.

11 sourcespapers-2026-11-12-0.1.0

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ConductScience Library. Lipid droplet dynamics in type 2 diabetes and its complications: pathophysiological insights and therapeutic options. Papers, record 40988015. Release papers-2026-11-12-0.1.0, 12 Nov 2026. https://conductscience.org/library/papers/40988015

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Paper

PubMed's record of the paper, with iCite's citation figures. No abstract is shown.

Title
Lipid droplet dynamics in type 2 diabetes and its complications: pathophysiological insights and therapeutic options.
PubMed
Journal
Lipids Health Dis
PubMed
Year
2025
PubMed
Publication types
Journal Article, Review
PubMed
Citations, by iCite
6
iCite
Relative citation ratio, by iCite
1.99, provisional
iCite
Revised in PubMed
2025-09-27
PubMed

Authors8

The authors in the order PubMed's record lists them, with the ORCID iDs it states.

OrderAuthorForenameKindORCID iD
1Long CCaiyi
2Li ZZihan
3Jiang LLiangliang
4Yang XXinyu
5Deng SSiyu
6Jiang YYayi
7Zhang BBoxun
8Yue RRensong

Source PubMed

Topics10

NLM's MeSH indexing of the paper, its major topics first.

MeSH termMajor
Diabetes Mellitus, Type 2Major topic
Lipid DropletsMajor topic
Humans
Lipid Metabolism
Animals
Insulin-Secreting Cells
Adipose Tissue
Hypoglycemic Agents
Lipolysis
Fatty Acids, Nonesterified

Source PubMed

Grants4

Each grant PubMed's record writes, matched to the NIH project NIH's grant and paper links name for this paper, and each of those links the record does not write.

Grant, as the record writes itAgencyCountryNIH projectStated by
No. 82274486the National Natural Science Foundation of ChinaPubMed
No. WXLH202402006the Joint Innovation Fund of Health Commission of Chengdu and Chengdu University of Traditional Chinese MedicinePubMed
No.2024zd007the Major Clinical Research Program of Sichuan Provincial Administration of Traditional Chinese MedicinePubMed
Sichuan Cadre Healthcare Research ZH2024-501Key Research and Development Project for Cadre Healthcare of Sichuan Provincial Health CommissionPubMed

Source PubMed

Trials0

The trials whose ClinicalTrials.gov record lists the paper, and the trial numbers the paper's PubMed record names.

None in this release.

Comments and corrections0

PubMed's comments and corrections, NLM's own indexing: retractions first, then expressions of concern, errata and updates, and comments last.

None in this release.

References306

The papers the reference list in PubMed's record names, those in our copy of PubMed, in the list's order.

OrderPMIDTitleJournalYearIn PapersSource
138,802,378Hairpin protein partitioning from the ER to lipid droplets involves major structural rearrangements.Nat Commun2024https://conductscience.org/library/papers/38802378PubMed
225,896,009Inflammatory stress exacerbates lipid accumulation and podocyte injuries in diabetic nephropathy.Acta Diabetol2015https://conductscience.org/library/papers/25896009PubMed
335,633,317AUP1 regulates lipid metabolism and induces lipid accumulation to accelerate the progression of renal clear cell carcinoma.Cancer Sci2022https://conductscience.org/library/papers/35633317PubMed
435,132,760An RDH-Plin2 axis modulates lipid droplet size by antagonizing Bmm lipase.EMBO Rep2022https://conductscience.org/library/papers/35132760PubMed
532,405,364Protection of renal damage by HMG-CoA inhibitors: A comparative study between atorvastatin and rosuvastatin.Iran J Basic Med Sci2020https://conductscience.org/library/papers/32405364PubMed
627,076,784Multi-Strain Probiotics Inhibit Cardiac Myopathies and Autophagy to Prevent Heart Injury in High-Fat Diet-Fed Rats.Int J Med Sci2016https://conductscience.org/library/papers/27076784PubMed
725,748,612Genetic risk, coronary heart disease events, and the clinical benefit of statin therapy: an analysis of primary and secondary prevention trials.Lancet2015https://conductscience.org/library/papers/25748612PubMed
834,433,630Lipid Droplets Protect Human β-Cells From Lipotoxicity-Induced Stress and Cell Identity Changes.Diabetes2021https://conductscience.org/library/papers/34433630PubMed
932,733,268The Vicious Cycle of Renal Lipotoxicity and Mitochondrial Dysfunction.Front Physiol2020https://conductscience.org/library/papers/32733268PubMed
1038,931,396Preventing High Fat Diet-Induced Obesity and Related Hepatic Steatosis by Chlorin e6-Mediated Photodynamic Therapy.Pharmaceuticals (Basel)2024https://conductscience.org/library/papers/38931396PubMed

1 to 10 of 306

See all 306 references

Cited by7

The papers in our copy of PubMed whose reference list names this one, newest first. iCite, which reads more sources, counts 6 citations.

PMIDTitleJournalYearIn PapersSource
42,859,241Metabolic stress remodels the Golgi-sphingolipid-lipid droplet axis in INS-1E β-cells: an integrated molecular signature of early β-cell vulnerability.Mol Biol Rep2026https://conductscience.org/library/papers/42859241PubMed
42,560,458High follicular fluid levels of 25-hydroxycholesterol might lead to increased number of lipid droplets in granulosa cells in polyendocrine metabolic ovarian syndrome (PMOS): a hypothesis.J Endocrinol Invest2026https://conductscience.org/library/papers/42560458PubMed
42,500,131Nontraditional lipid and lipid-inflammatory parameters for risk stratification of abnormal glucose metabolism: a cross-sectional study in Chinese adults.Front Endocrinol (Lausanne)2026https://conductscience.org/library/papers/42500131PubMed
42,305,344Understanding the link between lipid and ocular disorders for effective therapy.Arch Med Sci2026https://conductscience.org/library/papers/42305344PubMed
42,278,470Molecular Hydrogen as a Regulator of Mitochondrial Quality Control and Metabolic Reprogramming.Int J Mol Sci2026https://conductscience.org/library/papers/42278470PubMed
41,754,829Mechanistic Investigation of Astragalus Root in the Management of T2DM-NAFLD Comorbidity: An Integrated Network Pharmacology, Molecular Docking, Molecular Dynamics Simulation, and In Vitro Study.Pharmaceuticals (Basel)2026https://conductscience.org/library/papers/41754829PubMed
41,594,656BDH1 Mediates Aerobic Exercise-Induced Improvement in Skeletal Muscle Metabolic Remodeling in Type 2 Diabetes Mellitus.Biomolecules2026https://conductscience.org/library/papers/41594656PubMed

Genes1

The genes the Gene search release ties to the paper: Swiss-Prot's references first, then PubTator's text mining.

GeneNCBI Gene IDLinked byIn Genes
INS3,630PubTator's text mininghttps://conductscience.org/library/genes/3630

Source NCBI Gene

Drugs0

The drugs whose trials, in the Pipelines release, list the paper.

None in this release.

Data0

The data bank entries PubMed's record names. Trial numbers are under Trials.

None in this release.

Data dates

The date of each source this release read.

PubMed
2026-11-06
PubMed
iCite
2026-11-05
iCite
PMC's ID file
2026-11-05
PMC's ID file
NIH RePORTER's grant and paper links
2026-11-01
NIH RePORTER's grant and paper links
Trials
2026-11-12
Gene search
2026-11-11
Pipelines
2026-09-18

Sources 11

  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • HGNCCC0
  • iCiteCC BY 4.0
  • NCBI GenePublic domain (US government)
  • NIH RePORTER's grant and paper linksPublic domain
  • Open TargetsCC0 1.0
  • PMC's ID filePublic domain (US government)
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • HGNCCC0: https://www.genenames.org/about/license/
  • iCiteCC BY 4.0
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH RePORTER's grant and paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PMC's ID fileNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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