Paper · 41277604

TKC-MC: An Effective Strategy for Generating Heritable Heterozygous Mutations in Essential Genes in Rice.

Xu M and 9 others. Plant Biotechnol J, 2026. Cited by 1 paper, by iCite.

11 sourcespapers-2026-11-12-0.1.0

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ConductScience Library. TKC-MC: An Effective Strategy for Generating Heritable Heterozygous Mutations in Essential Genes in Rice. Papers, record 41277604. Release papers-2026-11-12-0.1.0, 12 Nov 2026. https://conductscience.org/library/papers/41277604

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Paper

PubMed's record of the paper, with iCite's citation figures. No abstract is shown.

Title: TKC-MC: An Effective Strategy for Generating Heritable Heterozygous Mutations in Essential Genes in Rice.; PubMed
Journal: Plant Biotechnol J; PubMed
Year: 2026; PubMed
Publication types: Journal Article; PubMed
PubMed: https://pubmed.ncbi.nlm.nih.gov/41277604/; PubMed
DOI: https://doi.org/10.1111/pbi.70472; PubMed
PMC: https://pmc.ncbi.nlm.nih.gov/articles/PMC13140513/; PubMed
The journal: https://conductscience.org/library/journal-index/101201889; PubMed
Citations, by iCite: 1; iCite
Revised in PubMed: 2026-08-13; PubMed

Authors10

The authors in the order PubMed's record lists them, with the ORCID iDs it states.

Order	Author	Forename	ORCID iD
1	Xu M	Meilian
2	Yan L	Lang
3	Zhu M	Min
4	Zhan Z	Zhitian
5	Chen H	Hong
6	Wang D	Dantong
7	Zheng Z	Zhenping
8	Zhang Y	Yujie
9	Xiong L	Lizhong	https://orcid.org/0000-0003-0490-1474
10	He Y	Yubing

Source PubMed

Topics9

NLM's MeSH indexing of the paper, its major topics first.

MeSH term	Major
Oryza	Major topic
Gene Editing	Major topic
CRISPR-Cas Systems	Major topic
Mutation	Major topic
Genes, Essential	Major topic
Genes, Plant	Major topic
Heterozygote
Plants, Genetically Modified
RNA, Guide, CRISPR-Cas Systems

Source PubMed

Grants7

Each grant PubMed's record writes, matched to the NIH project NIH's grant and paper links name for this paper, and each of those links the record does not write.

Grant, as the record writes it	Agency	Stated by
2023ZD04074	Biological Breeding-Major Projects	PubMed
32200335	National Natural Science Foundation of China	PubMed
U21A20207	National Natural Science Foundation of China	PubMed
Y2023QC39	Youth innovation Program of Chinese Academy of Agricultural Sciences	PubMed
YBXM2504	Nanfan special project of CAAS	PubMed
YBXM2505	Nanfan special project of CAAS	PubMed
CARS-01	Earmarked Fund for China Agriculture Research System	PubMed

Source PubMed

Trials0

The trials whose ClinicalTrials.gov record lists the paper, and the trial numbers the paper's PubMed record names.

None in this release.

Comments and corrections0

PubMed's comments and corrections, NLM's own indexing: retractions first, then expressions of concern, errata and updates, and comments last.

None in this release.

References63

The papers the reference list in PubMed's record names, those in our copy of PubMed, in the list's order.

Order	PMID	Title	Journal	Year	In Papers	Source
1	26,735,016	High-fidelity CRISPR-Cas9 nucleases with no detectable genome-wide off-target effects.	Nature	2016	https://conductscience.org/library/papers/26735016	PubMed
2	24,279,881	An in planta, Agrobacterium-mediated transient gene expression method for inducing gene silencing in rice (Oryza sativa L.) leaves.	Rice (N Y)	2012	https://conductscience.org/library/papers/24279881	PubMed
3	30,078,724	Kinetic Basis for DNA Target Specificity of CRISPR-Cas12a.	Mol Cell	2018	https://conductscience.org/library/papers/30078724	PubMed
4	23,873,081	DNA targeting specificity of RNA-guided Cas9 nucleases.	Nat Biotechnol	2013	https://conductscience.org/library/papers/23873081	PubMed
5	32,217,751	Unconstrained genome targeting with near-PAMless engineered CRISPR-Cas9 variants.	Science	2020	https://conductscience.org/library/papers/32217751	PubMed
6	32,042,045	Specificity profiling of CRISPR system reveals greatly enhanced off-target gene editing.	Sci Rep	2020	https://conductscience.org/library/papers/32042045	PubMed
7	34,619,328	A FLASH pipeline for arrayed CRISPR library construction and the gene function discovery of rice receptor-like kinases.	Mol Plant	2022	https://conductscience.org/library/papers/34619328	PubMed
8	24,463,574	Improving CRISPR-Cas nuclease specificity using truncated guide RNAs.	Nat Biotechnol	2014	https://conductscience.org/library/papers/24463574	PubMed
9	36,430,368	Structure- and Content-Dependent Efficiency of Cas9-Assisted DNA Cleavage in Genome-Editing Systems.	Int J Mol Sci	2022	https://conductscience.org/library/papers/36430368	PubMed
10	28,098,181	Profiling single-guide RNA specificity reveals a mismatch sensitive core sequence.	Sci Rep	2017	https://conductscience.org/library/papers/28098181	PubMed

1 to 10 of 63

See all 63 references

Cited by1

The papers in our copy of PubMed whose reference list names this one, newest first. iCite, which reads more sources, counts 1 citation.

PMID	Title	Journal	Year	In Papers
42,117,889	Negative Regulators of Rice Agronomic Traits: Functional Insights and Applications in Genome Editing-Based Breeding.	Plant Biotechnol J	2026	https://conductscience.org/library/papers/42117889

Source PubMed

Genes0

The genes the Gene search release ties to the paper: Swiss-Prot's references first, then PubTator's text mining.

None in this release.

Drugs0

The drugs whose trials, in the Pipelines release, list the paper.

None in this release.

Data0

The data bank entries PubMed's record names. Trial numbers are under Trials.

None in this release.

Data dates

The date of each source this release read.

PubMed: 2026-11-06; PubMed
iCite: 2026-11-05; iCite
PMC's ID file: 2026-11-05; PMC's ID file
NIH RePORTER's grant and paper links: 2026-11-01; NIH RePORTER's grant and paper links
Trials: 2026-11-12
Gene search: 2026-11-11
Pipelines: 2026-09-18

Sources 11

ChEMBL, through Open TargetsCC BY-SA 3.0
ClinicalTrials.govNo license stated
HGNCCC0
iCiteCC BY 4.0
NCBI GenePublic domain (US government)
NIH RePORTER's grant and paper linksPublic domain
Open TargetsCC0 1.0
PMC's ID filePublic domain (US government)
PubMedNLM's terms
PubTator 3Public domain
UniProtCC BY 4.0

Each source's terms

ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
ClinicalTrials.govnone stated
HGNCCC0: https://www.genenames.org/about/license/
iCiteCC BY 4.0
NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
NIH RePORTER's grant and paper linksPublic domain (NIH RePORTER)
Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
PMC's ID fileNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
PubMedNLM's terms
PubTator 3Public domain
UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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