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Paper · 4132995

Induction of immunological tolerance to a thymus-dependent antigen in the absence of thymus-derived cells.

Schrader JW. J Exp Med, 1974. Cited by 52 papers, by iCite.

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ConductScience Library. Induction of immunological tolerance to a thymus-dependent antigen in the absence of thymus-derived cells. Papers, record 4132995. Release papers-2026-11-12-0.1.0, 12 Nov 2026. https://conductscience.org/library/papers/4132995

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Paper

PubMed's record of the paper, with iCite's citation figures. No abstract is shown.

Title
Induction of immunological tolerance to a thymus-dependent antigen in the absence of thymus-derived cells.
PubMed
Journal
J Exp Med
PubMed
Year
1974
PubMed
Publication types
Journal Article
PubMed
Citations, by iCite
52
iCite
Relative citation ratio, by iCite
1.19
iCite
Revised in PubMed
2019-05-08
PubMed

Authors1

The authors in the order PubMed's record lists them, with the ORCID iDs it states.

OrderAuthorForenameKindORCID iD
1Schrader JWJ W

Source PubMed

Topics17

NLM's MeSH indexing of the paper, its major topics first.

MeSH termMajor
B-LymphocytesMajor topic
Immune ToleranceMajor topic
T-LymphocytesMajor topic
Animals
Antigens
Antigens, Bacterial
Birds
Dinitrophenols
Flagella
Immunization
Iodine Radioisotopes
Kinetics
Mice
Mice, Inbred Strains
Salmonella
Spleen
gamma-Globulins

Source PubMed

Grants0

Each grant PubMed's record writes, matched to the NIH project NIH's grant and paper links name for this paper, and each of those links the record does not write.

None in this release.

Trials0

The trials whose ClinicalTrials.gov record lists the paper, and the trial numbers the paper's PubMed record names.

None in this release.

Comments and corrections0

PubMed's comments and corrections, NLM's own indexing: retractions first, then expressions of concern, errata and updates, and comments last.

None in this release.

References28

The papers the reference list in PubMed's record names, those in our copy of PubMed, in the list's order.

OrderPMIDTitleJournalYearIn PapersSource
114,978,866Immunological unresponsiveness of genetically thymusless (nude) mice.Eur J Immunol1971https://conductscience.org/library/papers/14978866PubMed
24,958,328Use of an antiglobulin serum to detect cells producing antibody with low haemolytic efficiency.Nature1965https://conductscience.org/library/papers/4958328PubMed
34,194,660A theory of self-nonself discrimination.Science1970https://conductscience.org/library/papers/4194660PubMed
44,926,143The immune response of normal, irradiated and thymectomized mice to fowl immunoglobulin G as detected by a hemolytic plaque technique.Int Arch Allergy Appl Immunol1971https://conductscience.org/library/papers/4926143PubMed
54,103,761Induction of immunity and tolerance to the dinitrophenyl determinant in vitro.Nat New Biol1971https://conductscience.org/library/papers/4103761PubMed
64,104,294The relationship between antigenic structure and the requirement for thymus-derived cells in the immune response.J Exp Med1971https://conductscience.org/library/papers/4104294PubMed
74,397,662
Carrier function in anti-hapten antibody responses. IV. Experimental conditions for the induction of hapten-specific tolerance or for the stimulation of anti-hapten anamnestic responses by "nonimmunogenic" hapten-polypeptide conjugates.
J Exp Med1971https://conductscience.org/library/papers/4397662PubMed
84,105,624Cooperating and controlling functions of thymus-derived lymphocytes in relation to autoimmunity.Lancet1971https://conductscience.org/library/papers/4105624PubMed
94,399,419Interaction between lymphocytes in immune responses.Cell Immunol1971https://conductscience.org/library/papers/4399419PubMed
104,943,147Infectious immunological tolerance.Immunology1971https://conductscience.org/library/papers/4943147PubMed

1 to 10 of 28

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Cited by12

The papers in our copy of PubMed whose reference list names this one, newest first. iCite, which reads more sources, counts 52 citations.

PMIDTitleJournalYearIn PapersSource
7,108,445Deregulation of idiotype expression. Induction of tolerance in an anti-idiotypic response.J Exp Med1982https://conductscience.org/library/papers/7108445PubMed
6,446,426Current perspectives on the cellular mechanisms of immunologic tolerance.Clin Exp Immunol1980https://conductscience.org/library/papers/6446426PubMed
4,133,616Effector cell blockade. A new mechanism of immune hyporeactivity induced by multivalent antigens.J Exp Med1974https://conductscience.org/library/papers/4133616PubMed
1,079,510Tolerance induction in TxXBT and TxXB mice.Immunology1975https://conductscience.org/library/papers/1079510PubMed
811,749The allogeneic bisection of carrier-specific enhancement of monoclonal B-cell responses.J Exp Med1975https://conductscience.org/library/papers/811749PubMed
87,486Induction and mode of action of suppressor cells generated against human gamma globulin. II. Effects of colchicine.J Exp Med1979https://conductscience.org/library/papers/87486PubMed
87,485Tolerance induction during ontogeny. I. Presence of active suppression in mice rendered tolerant to human gamma-globulin in utero correlates with the breakdown of the tolerant state.J Exp Med1979https://conductscience.org/library/papers/87485PubMed
75,941Immunologic responsiveness of the C3H/HeJ mouse: differential ability of butanol-extracted lipopolysaccharide (LPS) to evoke LPS-mediated effects.J Exp Med1978https://conductscience.org/library/papers/75941PubMed
67,175
Differences in the mechanism of tolerance to dinitrophenylated bovine gamma globulin when induced in normal adult mice or in reconstituted irradiated mice: dependence of the mechanism of tolerance on the structural organization of the lymphoid system.
J Exp Med1977https://conductscience.org/library/papers/67175PubMed
47,898Tolerance induction in B lymphocytes but thymus-dependent antigens. T cells may abrogate B-cell tolerance induction by prevent an antibody response.J Exp Med1975https://conductscience.org/library/papers/47898PubMed

1 to 10 of 12

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Genes0

The genes the Gene search release ties to the paper: Swiss-Prot's references first, then PubTator's text mining.

None in this release.

Drugs0

The drugs whose trials, in the Pipelines release, list the paper.

None in this release.

Data0

The data bank entries PubMed's record names. Trial numbers are under Trials.

None in this release.

Data dates

The date of each source this release read.

PubMed
2026-11-06
PubMed
iCite
2026-11-05
iCite
PMC's ID file
2026-11-05
PMC's ID file
NIH RePORTER's grant and paper links
2026-11-01
NIH RePORTER's grant and paper links
Trials
2026-11-12
Gene search
2026-11-11
Pipelines
2026-09-18

Sources 11

  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • HGNCCC0
  • iCiteCC BY 4.0
  • NCBI GenePublic domain (US government)
  • NIH RePORTER's grant and paper linksPublic domain
  • Open TargetsCC0 1.0
  • PMC's ID filePublic domain (US government)
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • HGNCCC0: https://www.genenames.org/about/license/
  • iCiteCC BY 4.0
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH RePORTER's grant and paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PMC's ID fileNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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