ConductScience.org, home
Role of TREM2 in neuroinflammation regulation: mechanisms, disease associations, and therapeutic translation advances.
API referenceFor AI assistants

Paper · 41449430

References206

The papers the reference list in PubMed's record names, those in our copy of PubMed, in the list's order.

1 to 20 of 206

Download this page as JSON
OrderPMIDTitleJournalYearIn PapersSource
134,672,320Plasma sTREM2: a potential marker of cerebrovascular injury in neurodegenerative disorders.Brain2021https://conductscience.org/library/papers/34672320PubMed
237,917,301TREM2 Deficiency Aggravates NLRP3 Inflammasome Activation and Pyroptosis in MPTP-Induced Parkinson's Disease Mice and LPS-Induced BV2 Cells.Mol Neurobiol2024https://conductscience.org/library/papers/37917301PubMed
332,466,767TREM2 activation attenuates neuroinflammation and neuronal apoptosis via PI3K/Akt pathway after intracerebral hemorrhage in mice.J Neuroinflammation2020https://conductscience.org/library/papers/32466767PubMed
432,514,138Alzheimer's-associated PLCγ2 is a signaling node required for both TREM2 function and the inflammatory response in human microglia.Nat Neurosci2020https://conductscience.org/library/papers/32514138PubMed
533,065,553TREM2 ameliorates neuroinflammatory response and cognitive impairment via PI3K/AKT/FoxO3a signaling pathway in Alzheimer's disease mice.Aging (Albany NY)2020https://conductscience.org/library/papers/33065553PubMed
640,103,438TREM2 scFv-Engineering Escherichia coli Displaying Modulation of Macrophages to Boost Cancer Radio-Immunotherapy.Adv Mater2025https://conductscience.org/library/papers/40103438PubMed
738,865,485Microglia promote maladaptive plasticity in autonomic circuitry after spinal cord injury in mice.Sci Transl Med2024https://conductscience.org/library/papers/38865485PubMed
839,758,888Perioperative enriched environment attenuates postoperative cognitive dysfunction by upregulating microglia TREM2 via PI3K/Akt pathway in mouse model of ischemic stroke.Front Neurosci2024https://conductscience.org/library/papers/39758888PubMed
935,382,840CSF sTREM2 in neurological diseases: a two-sample Mendelian randomization study.J Neuroinflammation2022https://conductscience.org/library/papers/35382840PubMed
1026,949,937microRNA-34a-Mediated Down-Regulation of the Microglial-Enriched Triggering Receptor and Phagocytosis-Sensor TREM2 in Age-Related Macular Degeneration.PLoS One2016https://conductscience.org/library/papers/26949937PubMed
1136,852,060Neuroprotection by Nrf2 via modulating microglial phenotype and phagocytosis after intracerebral hemorrhage.Heliyon2023https://conductscience.org/library/papers/36852060PubMed
1221,956,652TREM-2, triggering receptor expressed on myeloid cell-2, negatively regulates TLR responses in dendritic cells.Eur J Immunol2012https://conductscience.org/library/papers/21956652PubMed
1326,374,508A basic overview of multiple sclerosis immunopathology.Eur J Neurol2015https://conductscience.org/library/papers/26374508PubMed
1431,134,514TREM2 Attenuates Aβ1-42-Mediated Neuroinflammation in BV-2 Cells by Downregulating TLR Signaling.Neurochem Res2019https://conductscience.org/library/papers/31134514PubMed
1535,247,489Downregulation of TREM2/NF-кB signaling may damage the blood-brain barrier and aggravate neuronal apoptosis in experimental rats with surgically injured brain.Brain Res Bull2022https://conductscience.org/library/papers/35247489PubMed
1639,722,698sTREM2 cerebrospinal fluid levels are a potential biomarker in amyotrophic lateral sclerosis and associate with UMN burden.Front Neurol2024https://conductscience.org/library/papers/39722698PubMed
1734,172,778Microglial signalling pathway deficits associated with the patient derived R47H TREM2 variants linked to AD indicate inability to activate inflammasome.Sci Rep2021https://conductscience.org/library/papers/34172778PubMed
1835,414,082Soluble TREM2 is associated with death and cardiovascular events after acute ischemic stroke: an observational study from CATIS.J Neuroinflammation2022https://conductscience.org/library/papers/35414082PubMed
1926,337,043TREM2 in CNS homeostasis and neurodegenerative disease.Mol Neurodegener2015https://conductscience.org/library/papers/26337043PubMed
2032,067,825Early increment of soluble triggering receptor expressed on myeloid cells 2 in plasma might be a predictor of poor outcome after ischemic stroke.J Clin Neurosci2020https://conductscience.org/library/papers/32067825PubMed

papers-2026-11-12-0.1.0

Next page

Sources 11

  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • HGNCCC0
  • iCiteCC BY 4.0
  • NCBI GenePublic domain (US government)
  • NIH RePORTER's grant and paper linksPublic domain
  • Open TargetsCC0 1.0
  • PMC's ID filePublic domain (US government)
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • HGNCCC0: https://www.genenames.org/about/license/
  • iCiteCC BY 4.0
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH RePORTER's grant and paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PMC's ID fileNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this list from software.

Twenty rows a page, as JSON. No key.

GET https://conductscience.org/api/papers/v1/41449430/references

API referenceFor AI assistants