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Paper · 41530266

Monitoring biological effects of somatic cell genome editing.

Freedman BS and 27 others. Nat Rev Genet, 2026. Cited by 8 papers, by iCite.

11 sourcespapers-2026-11-12-0.1.0

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ConductScience Library. Monitoring biological effects of somatic cell genome editing. Papers, record 41530266. Release papers-2026-11-12-0.1.0, 12 Nov 2026. https://conductscience.org/library/papers/41530266

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Paper

PubMed's record of the paper, with iCite's citation figures. No abstract is shown.

Title
Monitoring biological effects of somatic cell genome editing.
PubMed
Journal
Nat Rev Genet
PubMed
Year
2026
PubMed
Publication types
Journal Article, Review
PubMed
Citations, by iCite
8
iCite
Relative citation ratio, by iCite
4.95, provisional
iCite
Revised in PubMed
2026-11-02
PubMed

Authors28

The authors in the order PubMed's record lists them, with the ORCID iDs it states.

OrderAuthorForenameKindORCID iD
1Freedman BSBenjamin Shttps://orcid.org/0000-0003-2228-7383
2Bulte JWMJeff W Mhttps://orcid.org/0000-0003-1202-1610
3Conklin BRBruce R
4Judge LMLuke M
5Dwinell MRMelinda R
6Geurts AMAron M
7Sitton MJMadeleine J
8Mahajan VVineet
9Kiani SSamira
10Gersbach CACharles Ahttps://orcid.org/0000-0003-1478-4013

1 to 10 of 28Source PubMed

See all 28 authors

Topics6

NLM's MeSH indexing of the paper, its major topics first.

MeSH termMajor
Gene EditingMajor topic
CRISPR-Cas SystemsMajor topic
Genetic TherapyMajor topic
Humans
Animals
Microphysiological Systems

Source PubMed

Grants23

Each grant PubMed's record writes, matched to the NIH project NIH's grant and paper links name for this paper, and each of those links the record does not write.

Grant, as the record writes itAgencyCountryNIH projectStated bySource
UH2 EB028904NIBIB NIH HHSUnited StatesUH2EB028904PubMedNIH RePORTER
R01 NS119678NINDS NIH HHSUnited StatesR01NS119678PubMedNIH RePORTER
S10 OD016261NIH HHSUnited StatesS10OD016261PubMedNIH RePORTER
U01 EB028892NIBIB NIH HHSUnited StatesU01EB028892PubMedNIH RePORTER
U01 AI176460NIAID NIH HHSUnited StatesU01AI176460PubMedNIH RePORTER
U19 NS132296NINDS NIH HHSUnited StatesU19NS132296PubMedNIH RePORTER
R35 GM119644NIGMS NIH HHSUnited StatesR35GM119644PubMedNIH RePORTER
R01 AG072052NIA NIH HHSUnited StatesR01AG072052PubMedNIH RePORTER
S10 OD018102NIH HHSUnited StatesS10OD018102PubMedNIH RePORTER
U01 DK127553NIDDK NIH HHSUnited StatesU01DK127553PubMedNIH RePORTER

1 to 10 of 23

See all 23 grants

Trials0

The trials whose ClinicalTrials.gov record lists the paper, and the trial numbers the paper's PubMed record names.

None in this release.

Comments and corrections0

PubMed's comments and corrections, NLM's own indexing: retractions first, then expressions of concern, errata and updates, and comments last.

None in this release.

References228

The papers the reference list in PubMed's record names, those in our copy of PubMed, in the list's order.

OrderPMIDTitleJournalYearIn PapersSource
132,123,335Fast and efficient generation of knock-in human organoids using homology-independent CRISPR-Cas9 precision genome editing.Nat Cell Biol2020https://conductscience.org/library/papers/32123335PubMed
235,478,224Modelling ciliopathy phenotypes in human tissues derived from pluripotent stem cells with genetically ablated cilia.Nat Biomed Eng2022https://conductscience.org/library/papers/35478224PubMed
332,330,446Myogenic Progenitor Cell Lineage Specification by CRISPR/Cas9-Based Transcriptional Activators.Stem Cell Reports2020https://conductscience.org/library/papers/32330446PubMed
438,767,512AAV5 Delivery of CRISPR/Cas9 Mediates Genome Editing in the Lungs of Young Rhesus Monkeys.Hum Gene Ther2024https://conductscience.org/library/papers/38767512PubMed
536,589,903In Vivo Cellular Magnetic Imaging: Labeled vs. Unlabeled Cells.Adv Funct Mater2022https://conductscience.org/library/papers/36589903PubMed
630,664,785Development of a gene-editing approach to restore vision loss in Leber congenital amaurosis type 10.Nat Med2019https://conductscience.org/library/papers/30664785PubMed
733,097,693Prime editing for functional repair in patient-derived disease models.Nat Commun2020https://conductscience.org/library/papers/33097693PubMed
830,778,238Long-term evaluation of AAV-CRISPR genome editing for Duchenne muscular dystrophy.Nat Med2019https://conductscience.org/library/papers/30778238PubMed
934,188,077Concept for using magnetic particle imaging for intraoperative margin analysis in breast-conserving surgery.Sci Rep2021https://conductscience.org/library/papers/34188077PubMed
1032,857,373Frame-Hydrogel Methodology for Engineering Highly Functional Cardiac Tissue Constructs.Methods Mol Biol2021https://conductscience.org/library/papers/32857373PubMed

1 to 10 of 228

See all 228 references

Cited by8

The papers in our copy of PubMed whose reference list names this one, newest first. iCite, which reads more sources, counts 8 citations.

PMIDTitleJournalYearIn PapersSource
42,781,958CRISPR-Cas9 and precision editing technologies linking functional genomics to clinical translation in genetic diseases.Clin Transl Med2026https://conductscience.org/library/papers/42781958PubMed
42,719,520Exploring the role of CRISPR in advancing space biotechnology: challenges and solutions for human survival beyond earth.Front Bioeng Biotechnol2026https://conductscience.org/library/papers/42719520PubMed
42,608,275On-target and off-target activities of CRISPR therapeutics across scales.Trends Biotechnol2026https://conductscience.org/library/papers/42608275PubMed
42,486,668Editing around the target: epitope engineering to protect stem cell grafts.Blood Adv2026https://conductscience.org/library/papers/42486668PubMed
42,463,825Reversing cancer cell behavior using AI-guided CRISPR and quantum nanobiology: a systems-based approach to epigenetic reprogramming.Gene Ther2026https://conductscience.org/library/papers/42463825PubMed
42,436,857Combining modeling approaches for rapid preclinical evaluation of retinal gene therapy.Mol Ther Adv2026https://conductscience.org/library/papers/42436857PubMed
41,981,831Monitoring Fetal Somatic Cell Genome Editing In Vivo with Total-Body Positron Emission Tomography: Studies in Rhesus Macaques (Macaca mulatta).Hum Gene Ther2026https://conductscience.org/library/papers/41981831PubMed
41,933,615Towards clinical translation of nanomedicines: Formulation scale-up and model systems.Adv Drug Deliv Rev2026https://conductscience.org/library/papers/41933615PubMed

Genes0

The genes the Gene search release ties to the paper: Swiss-Prot's references first, then PubTator's text mining.

None in this release.

Drugs0

The drugs whose trials, in the Pipelines release, list the paper.

None in this release.

Data0

The data bank entries PubMed's record names. Trial numbers are under Trials.

None in this release.

Data dates

The date of each source this release read.

PubMed
2026-11-06
PubMed
iCite
2026-11-05
iCite
PMC's ID file
2026-11-05
PMC's ID file
NIH RePORTER's grant and paper links
2026-11-01
NIH RePORTER's grant and paper links
Trials
2026-11-12
Gene search
2026-11-11
Pipelines
2026-09-18

Sources 11

  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • HGNCCC0
  • iCiteCC BY 4.0
  • NCBI GenePublic domain (US government)
  • NIH RePORTER's grant and paper linksPublic domain
  • Open TargetsCC0 1.0
  • PMC's ID filePublic domain (US government)
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • HGNCCC0: https://www.genenames.org/about/license/
  • iCiteCC BY 4.0
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH RePORTER's grant and paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PMC's ID fileNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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