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Paper · 41545706

Heterocellular crosstalk and architecture of the pancreatic tumour microenvironment.

Arnold F and 3 others. Nat Rev Cancer, 2026. Cited by 10 papers, by iCite.

11 sourcespapers-2026-11-12-0.1.0

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ConductScience Library. Heterocellular crosstalk and architecture of the pancreatic tumour microenvironment. Papers, record 41545706. Release papers-2026-11-12-0.1.0, 12 Nov 2026. https://conductscience.org/library/papers/41545706

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Paper

PubMed's record of the paper, with iCite's citation figures. No abstract is shown.

Title
Heterocellular crosstalk and architecture of the pancreatic tumour microenvironment.
PubMed
Journal
Nat Rev Cancer
PubMed
Year
2026
PubMed
Publication types
Journal Article, Review
PubMed
Citations, by iCite
10
iCite
Relative citation ratio, by iCite
5.14, provisional
iCite
Revised in PubMed
2026-11-03
PubMed

Authors4

The authors in the order PubMed's record lists them, with the ORCID iDs it states.

OrderAuthorForenameKindORCID iD
1Arnold FFrankhttps://orcid.org/0000-0003-0025-3668
2Del Vecchio AAnnachiara
3Hussain ZZainab
4Sherman MHMara Hhttps://orcid.org/0000-0001-7826-3888

Source PubMed

Topics5

NLM's MeSH indexing of the paper, its major topics first.

MeSH termMajor
Tumor MicroenvironmentMajor topic
Pancreatic NeoplasmsMajor topic
Humans
Animals
Signal Transduction

Source PubMed

Grants0

Each grant PubMed's record writes, matched to the NIH project NIH's grant and paper links name for this paper, and each of those links the record does not write.

None in this release.

Trials0

The trials whose ClinicalTrials.gov record lists the paper, and the trial numbers the paper's PubMed record names.

None in this release.

Comments and corrections0

PubMed's comments and corrections, NLM's own indexing: retractions first, then expressions of concern, errata and updates, and comments last.

None in this release.

References311

The papers the reference list in PubMed's record names, those in our copy of PubMed, in the list's order.

OrderPMIDTitleJournalYearIn PapersSource
128,685,754Collagen-derived proline promotes pancreatic ductal adenocarcinoma cell survival under nutrient limited conditions.Nat Commun2017https://conductscience.org/library/papers/28685754PubMed
239,535,921Cancer-associated fibroblasts maintain critical pancreatic cancer cell lipid homeostasis in the tumor microenvironment.Cell Rep2024https://conductscience.org/library/papers/39535921PubMed
338,521,881NNT-AS1 in CAFs-derived exosomes promotes progression and glucose metabolism through miR-889-3p/HIF-1α in pancreatic adenocarcinoma.Sci Rep2024https://conductscience.org/library/papers/38521881PubMed
440,138,590Cancer-Associated Fibroblasts Foster a High-Lactate Microenvironment to Drive Perineural Invasion in Pancreatic Cancer.Cancer Res2025https://conductscience.org/library/papers/40138590PubMed
534,644,529Spatially confined sub-tumor microenvironments in pancreatic cancer.Cell2021https://conductscience.org/library/papers/34644529PubMed
620,308,362Lymph node fibroblastic reticular cells directly present peripheral tissue antigen under steady-state and inflammatory conditions.J Exp Med2010https://conductscience.org/library/papers/20308362PubMed
724,650,449Chronic stress accelerates pancreatic cancer growth and invasion: a critical role for beta-adrenergic signaling in the pancreatic microenvironment.Brain Behav Immun2014https://conductscience.org/library/papers/24650449PubMed
830,355,799Suppression of stromal-derived Dickkopf-3 (DKK3) inhibits tumor progression and prolongs survival in pancreatic ductal adenocarcinoma.Sci Transl Med2018https://conductscience.org/library/papers/30355799PubMed
939,817,679Cancer statistics, 2025.CA Cancer J Clin2025https://conductscience.org/library/papers/39817679PubMed
1026,883,357Genetics and biology of pancreatic ductal adenocarcinoma.Genes Dev2016https://conductscience.org/library/papers/26883357PubMed

1 to 10 of 311

See all 311 references

Cited by8

The papers in our copy of PubMed whose reference list names this one, newest first. iCite, which reads more sources, counts 10 citations.

PMIDTitleJournalYearIn PapersSource
42,941,878CGRP-RAMP1/CALCRL Signaling Drives TGF-β2-Mediated Immune Evasion and Pancreatic Cancer Progression.Int J Mol Sci2026https://conductscience.org/library/papers/42941878PubMed
42,749,762Tumour cells shape their environment to protect them from the immune system.Nature2026https://conductscience.org/library/papers/42749762PubMed
42,717,081A serpin-myeloid axis in pancreatic cancer heterogeneity and immune evasion.Nature2026https://conductscience.org/library/papers/42717081PubMed
42,707,690Immunosuppressive cells as barriers to cancer therapy: mechanisms and emerging solutions.Front Immunol2026https://conductscience.org/library/papers/42707690PubMed
42,602,543The interplay between oncolytic viruses, Toll-like receptor signaling, and chemotherapy in overcoming tumor immune tolerance.Front Cell Infect Microbiol2026https://conductscience.org/library/papers/42602543PubMed
42,512,419
Cancer-Associated Fibroblast Heterogeneity and Extracellular Matrix Remodeling as Orchestrators of Drug Resistance in Upper Gastrointestinal Cancers: Insights from Spatial Multi-Omics and Therapeutic Implications.
Cancers (Basel)2026https://conductscience.org/library/papers/42512419PubMed
42,192,869Hypoxia Impairs CD8+ T Cell Fitness and Is Associated with a Dysfunctional CD8+ T Cell State in Pancreatic Cancer.Cancers (Basel)2026https://conductscience.org/library/papers/42192869PubMed
42,080,091Neural-immune-cancer crosstalk in pancreatic cancer: mechanisms and clinical translation.Front Cell Dev Biol2026https://conductscience.org/library/papers/42080091PubMed

Genes1

The genes the Gene search release ties to the paper: Swiss-Prot's references first, then PubTator's text mining.

GeneNCBI Gene IDLinked byIn Genes
KRAS3,845PubTator's text mininghttps://conductscience.org/library/genes/3845

Source NCBI Gene

Drugs0

The drugs whose trials, in the Pipelines release, list the paper.

None in this release.

Data0

The data bank entries PubMed's record names. Trial numbers are under Trials.

None in this release.

Data dates

The date of each source this release read.

PubMed
2026-11-06
PubMed
iCite
2026-11-05
iCite
PMC's ID file
2026-11-05
PMC's ID file
NIH RePORTER's grant and paper links
2026-11-01
NIH RePORTER's grant and paper links
Trials
2026-11-12
Gene search
2026-11-11
Pipelines
2026-09-18

Sources 11

  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • HGNCCC0
  • iCiteCC BY 4.0
  • NCBI GenePublic domain (US government)
  • NIH RePORTER's grant and paper linksPublic domain
  • Open TargetsCC0 1.0
  • PMC's ID filePublic domain (US government)
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • HGNCCC0: https://www.genenames.org/about/license/
  • iCiteCC BY 4.0
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH RePORTER's grant and paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PMC's ID fileNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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