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Paper · 41597184

Studies of Foxo1 over the Past 25 Years: Mechanisms of Insulin Resistance and Glucose Dysregulation.

Yang W and 3 others. Cells, 2026. Cited by 2 papers, by iCite.

11 sourcespapers-2026-11-12-0.1.0

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ConductScience Library. Studies of Foxo1 over the Past 25 Years: Mechanisms of Insulin Resistance and Glucose Dysregulation. Papers, record 41597184. Release papers-2026-11-12-0.1.0, 12 Nov 2026. https://conductscience.org/library/papers/41597184

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Paper

PubMed's record of the paper, with iCite's citation figures. No abstract is shown.

Title
Studies of Foxo1 over the Past 25 Years: Mechanisms of Insulin Resistance and Glucose Dysregulation.
PubMed
Journal
Cells
PubMed
Year
2026
PubMed
Publication types
Journal Article, Review
PubMed
Citations, by iCite
2
iCite
Revised in PubMed
2026-07-01
PubMed

Authors4

The authors in the order PubMed's record lists them, with the ORCID iDs it states.

OrderAuthorForenameKindORCID iD
1Yang WWanbao
2Guo JJeffrey
3Song JJianxunhttps://orcid.org/0000-0002-9734-6176
4Guo SShaodonghttps://orcid.org/0000-0001-5126-731X

Source PubMed

Topics7

NLM's MeSH indexing of the paper, its major topics first.

MeSH termMajor
Forkhead Box Protein O1Major topic
Insulin ResistanceMajor topic
GlucoseMajor topic
Humans
Animals
Signal Transduction
Energy Metabolism

Source PubMed

Grants2

Each grant PubMed's record writes, matched to the NIH project NIH's grant and paper links name for this paper, and each of those links the record does not write.

Grant, as the record writes itAgencyCountryNIH projectStated bySource
1R01DK120968-19NIH HHSUnited StatesR01DK120968PubMedNIH RePORTER
1R01DK124588-21NIH HHSUnited StatesR01DK124588PubMedNIH RePORTER

Trials0

The trials whose ClinicalTrials.gov record lists the paper, and the trial numbers the paper's PubMed record names.

None in this release.

Comments and corrections0

PubMed's comments and corrections, NLM's own indexing: retractions first, then expressions of concern, errata and updates, and comments last.

None in this release.

References131

The papers the reference list in PubMed's record names, those in our copy of PubMed, in the list's order.

OrderPMIDTitleJournalYearIn PapersSource
115,316,008SH2-B promotes insulin receptor substrate 1 (IRS1)- and IRS2-mediated activation of the phosphatidylinositol 3-kinase pathway in response to leptin.J Biol Chem2004https://conductscience.org/library/papers/15316008PubMed
218,590,693Inactivation of hepatic Foxo1 by insulin signaling is required for adaptive nutrient homeostasis and endocrine growth regulation.Cell Metab2008https://conductscience.org/library/papers/18590693PubMed
333,761,350FoxO1 suppresses Fgf21 during hepatic insulin resistance to impair peripheral glucose utilization and acute cold tolerance.Cell Rep2021https://conductscience.org/library/papers/33761350PubMed
423,684,624Adiponectin regulates bone mass via opposite central and peripheral mechanisms through FoxO1.Cell Metab2013https://conductscience.org/library/papers/23684624PubMed
532,244,542Adipose Tissue and FoxO1: Bridging Physiology and Mechanisms.Cells2020https://conductscience.org/library/papers/32244542PubMed
615,879,087TGF-beta 1 uses distinct mechanisms to inhibit IFN-gamma expression in CD4+ T cells at priming and at recall: differential involvement of Stat4 and T-bet.J Immunol2005https://conductscience.org/library/papers/15879087PubMed
729,431,075The Role of Forkhead Box 1 (FOXO1) in the Immune System: Dendritic Cells, T Cells, B Cells, and Hematopoietic Stem Cells.Crit Rev Immunol2017https://conductscience.org/library/papers/29431075PubMed
824,379,407Control of Foxo1 gene expression by co-activator P300.J Biol Chem2014https://conductscience.org/library/papers/24379407PubMed
937,156,218FoxO1 regulates adipose transdifferentiation and iron influx by mediating Tgfβ1 signaling pathway.Redox Biol2023https://conductscience.org/library/papers/37156218PubMed
1018,978,794Distinct functions for the transcription factor Foxo1 at various stages of B cell differentiation.Nat Immunol2008https://conductscience.org/library/papers/18978794PubMed

1 to 10 of 131

See all 131 references

Cited by2

The papers in our copy of PubMed whose reference list names this one, newest first. iCite, which reads more sources, counts 2 citations.

PMIDTitleJournalYearIn PapersSource
42,581,371Follicle-stimulating hormone promotes energy metabolism in bovine granulosa cells through the FOXO1-ISG15 pathway to maintain the development of multiple follicles.J Anim Sci Biotechnol2026https://conductscience.org/library/papers/42581371PubMed
42,199,525Cellular signaling crosstalk between osteoporosis and diabetes: Common mechanisms and therapeutic targets (Review).Biomed Rep2026https://conductscience.org/library/papers/42199525PubMed

Genes2

The genes the Gene search release ties to the paper: Swiss-Prot's references first, then PubTator's text mining.

GeneNCBI Gene IDLinked byIn GenesSource
FOXO12,308PubTator's text mininghttps://conductscience.org/library/genes/2308NCBI Gene
INS3,630PubTator's text mininghttps://conductscience.org/library/genes/3630NCBI Gene

Drugs0

The drugs whose trials, in the Pipelines release, list the paper.

None in this release.

Data0

The data bank entries PubMed's record names. Trial numbers are under Trials.

None in this release.

Data dates

The date of each source this release read.

PubMed
2026-11-06
PubMed
iCite
2026-11-05
iCite
PMC's ID file
2026-11-05
PMC's ID file
NIH RePORTER's grant and paper links
2026-11-01
NIH RePORTER's grant and paper links
Trials
2026-11-12
Gene search
2026-11-11
Pipelines
2026-09-18

Sources 11

  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • HGNCCC0
  • iCiteCC BY 4.0
  • NCBI GenePublic domain (US government)
  • NIH RePORTER's grant and paper linksPublic domain
  • Open TargetsCC0 1.0
  • PMC's ID filePublic domain (US government)
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • HGNCCC0: https://www.genenames.org/about/license/
  • iCiteCC BY 4.0
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH RePORTER's grant and paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PMC's ID fileNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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