Paper · 41712875

Current Insights and Future Directions of Multiomic and Spatial-Omic Analysis in Non-Small Cell Lung Cancer.

Church M and 2 others. JCO Precis Oncol, 2026. Cited by 1 paper, by iCite.

11 sourcespapers-2026-11-12-0.1.0

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ConductScience Library. Current Insights and Future Directions of Multiomic and Spatial-Omic Analysis in Non-Small Cell Lung Cancer. Papers, record 41712875. Release papers-2026-11-12-0.1.0, 12 Nov 2026. https://conductscience.org/library/papers/41712875

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Paper

PubMed's record of the paper, with iCite's citation figures. No abstract is shown.

Title: Current Insights and Future Directions of Multiomic and Spatial-Omic Analysis in Non-Small Cell Lung Cancer.; PubMed
Journal: JCO Precis Oncol; PubMed
Year: 2026; PubMed
Publication types: Journal Article, Review; PubMed
PubMed: https://pubmed.ncbi.nlm.nih.gov/41712875/; PubMed
DOI: https://doi.org/10.1200/po-25-00684; PubMed
PMC: https://pmc.ncbi.nlm.nih.gov/articles/PMC12931866/; PubMed
The journal: https://conductscience.org/library/journal-index/101705370; PubMed
Citations, by iCite: 1; iCite
Revised in PubMed: 2026-08-13; PubMed

Authors3

The authors in the order PubMed's record lists them, with the ORCID iDs it states.

Order	Author	Forename	ORCID iD
1	Church M	Matt	https://orcid.org/0000-0002-5825-3241
2	Marshall G	Gayle
3	Krebs MG	Matthew G	https://orcid.org/0000-0001-7540-3064

Source PubMed

Topics8

NLM's MeSH indexing of the paper, its major topics first.

MeSH term	Major
Carcinoma, Non-Small-Cell Lung	Major topic
Multiomics	Major topic
Lung Neoplasms	Major topic
Humans
Precision Medicine
Genomics
Proteomics
Metabolomics

Source PubMed

Grants0

Each grant PubMed's record writes, matched to the NIH project NIH's grant and paper links name for this paper, and each of those links the record does not write.

None in this release.

Trials0

The trials whose ClinicalTrials.gov record lists the paper, and the trial numbers the paper's PubMed record names.

None in this release.

Comments and corrections0

PubMed's comments and corrections, NLM's own indexing: retractions first, then expressions of concern, errata and updates, and comments last.

None in this release.

References141

The papers the reference list in PubMed's record names, those in our copy of PubMed, in the list's order.

Order	PMID	Title	Journal	Year	In Papers	Source
1	9,751,761	Aberrant methylation of p16(INK4a) is an early event in lung cancer and a potential biomarker for early diagnosis.	Proc Natl Acad Sci U S A	1998	https://conductscience.org/library/papers/9751761	PubMed
2	39,726,591	TLS and immune cell profiling: immunomodulatory effects of immunochemotherapy on tumor microenvironment in resectable stage III NSCLC.	Front Immunol	2024	https://conductscience.org/library/papers/39726591	PubMed
3	33,916,417	Integrative RNA-Seq and H3 Trimethylation ChIP-Seq Analysis of Human Lung Cancer Cells Isolated by Laser-Microdissection.	Cancers (Basel)	2021	https://conductscience.org/library/papers/33916417	PubMed
4	31,548,600	The emerging role of epigenetic therapeutics in immuno-oncology.	Nat Rev Clin Oncol	2020	https://conductscience.org/library/papers/31548600	PubMed
5	36,203,011	High-plex imaging of RNA and proteins at subcellular resolution in fixed tissue by spatial molecular imaging.	Nat Biotechnol	2022	https://conductscience.org/library/papers/36203011	PubMed
6	37,022,147	Multi-omic and spatial dissection of immunotherapy response groups in non-small cell lung cancer.	Immunology	2023	https://conductscience.org/library/papers/37022147	PubMed
7	39,258,530	The prognosis and metabolite changes of NSCLC patients receiving first-line immunotherapy combined chemotherapy in different M1c categories according to 9th edition of TNM classification.	Cancer Med	2024	https://conductscience.org/library/papers/39258530	PubMed
8	35,490,853	Discovery of Biomarkers of Resistance to Immune Checkpoint Blockade in NSCLC Using High-Plex Digital Spatial Profiling.	J Thorac Oncol	2022	https://conductscience.org/library/papers/35490853	PubMed
9	39,143,582	Integrated omics characterization reveals reduced cancer indicators and elevated inflammatory factors after thermal ablation in non-small cell lung cancer patients.	Respir Res	2024	https://conductscience.org/library/papers/39143582	PubMed
10	41,073,787	Spatial signatures for predicting immunotherapy outcomes using multi-omics in non-small cell lung cancer.	Nat Genet	2025	https://conductscience.org/library/papers/41073787	PubMed

1 to 10 of 141

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Cited by1

The papers in our copy of PubMed whose reference list names this one, newest first. iCite, which reads more sources, counts 1 citation.

PMID	Title	Journal	Year	In Papers
42,591,661	FGFR1 copy number gain is independently associated with shorter progression-free survival in advanced lung squamous cell carcinoma treated with first-line immune checkpoint inhibitor-based therapy.	Front Immunol	2026	https://conductscience.org/library/papers/42591661

Source PubMed

Genes68

The genes the Gene search release ties to the paper: Swiss-Prot's references first, then PubTator's text mining.

Gene	NCBI Gene ID	Linked by	In Genes	Source
ADGRB1	575	PubTator's text mining	https://conductscience.org/library/genes/575	NCBI Gene
AKT1	207	PubTator's text mining	https://conductscience.org/library/genes/207	NCBI Gene
ATM	472	PubTator's text mining	https://conductscience.org/library/genes/472	NCBI Gene
BRCA1	672	PubTator's text mining	https://conductscience.org/library/genes/672	NCBI Gene
BSG	682	PubTator's text mining	https://conductscience.org/library/genes/682	NCBI Gene
CCL13	6,357	PubTator's text mining	https://conductscience.org/library/genes/6357	NCBI Gene
CCL19	6,363	PubTator's text mining	https://conductscience.org/library/genes/6363	NCBI Gene
CCL8	6,355	PubTator's text mining	https://conductscience.org/library/genes/6355	NCBI Gene
CCND3	896	PubTator's text mining	https://conductscience.org/library/genes/896	NCBI Gene
CD14	929	PubTator's text mining	https://conductscience.org/library/genes/929	NCBI Gene

1 to 10 of 68

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Drugs0

The drugs whose trials, in the Pipelines release, list the paper.

None in this release.

Data0

The data bank entries PubMed's record names. Trial numbers are under Trials.

None in this release.

Data dates

The date of each source this release read.

PubMed: 2026-11-06; PubMed
iCite: 2026-11-05; iCite
PMC's ID file: 2026-11-05; PMC's ID file
NIH RePORTER's grant and paper links: 2026-11-01; NIH RePORTER's grant and paper links
Trials: 2026-11-12
Gene search: 2026-11-11
Pipelines: 2026-09-18

Sources 11

ChEMBL, through Open TargetsCC BY-SA 3.0
ClinicalTrials.govNo license stated
HGNCCC0
iCiteCC BY 4.0
NCBI GenePublic domain (US government)
NIH RePORTER's grant and paper linksPublic domain
Open TargetsCC0 1.0
PMC's ID filePublic domain (US government)
PubMedNLM's terms
PubTator 3Public domain
UniProtCC BY 4.0

Each source's terms

ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
ClinicalTrials.govnone stated
HGNCCC0: https://www.genenames.org/about/license/
iCiteCC BY 4.0
NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
NIH RePORTER's grant and paper linksPublic domain (NIH RePORTER)
Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
PMC's ID fileNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
PubMedNLM's terms
PubTator 3Public domain
UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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