Paper · 41789596
Mechanisms and therapeutic potential of glycyrrhizic acid: Insights into key signaling pathways and disease modulation (Review).
Yu J and 5 others. Mol Med Rep, 2026. Cited by 4 papers, by iCite.
11 sourcespapers-2026-11-12-0.1.0
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ConductScience Library. Mechanisms and therapeutic potential of glycyrrhizic acid: Insights into key signaling pathways and disease modulation (Review). Papers, record 41789596. Release papers-2026-11-12-0.1.0, 12 Nov 2026. https://conductscience.org/library/papers/41789596
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Paper
PubMed's record of the paper, with iCite's citation figures. No abstract is shown.
- Title
- Mechanisms and therapeutic potential of glycyrrhizic acid: Insights into key signaling pathways and disease modulation (Review).
- PubMed
Topics7
NLM's MeSH indexing of the paper, its major topics first.
| MeSH term | Major |
|---|---|
| Glycyrrhizic Acid | Major topic |
| Signal Transduction | Major topic |
| Anti-Inflammatory Agents | Major topic |
| Humans | |
| Animals | |
| HMGB1 Protein | |
| NF-kappa B |
Source PubMed
Grants0
Each grant PubMed's record writes, matched to the NIH project NIH's grant and paper links name for this paper, and each of those links the record does not write.
None in this release.
Trials0
The trials whose ClinicalTrials.gov record lists the paper, and the trial numbers the paper's PubMed record names.
None in this release.
Comments and corrections0
PubMed's comments and corrections, NLM's own indexing: retractions first, then expressions of concern, errata and updates, and comments last.
None in this release.
References118
The papers the reference list in PubMed's record names, those in our copy of PubMed, in the list's order.
| Order | PMID | Title | Journal | Year | In Papers | Source |
|---|---|---|---|---|---|---|
| 1 | 40,122,507 | Glycyrrhizic acid alleviates gefitinib-induced liver injury by regulating the p53/p21 pathway and releasing cell cycle arrest. | Food Chem Toxicol | 2025 | https://conductscience.org/library/papers/40122507 | PubMed |
| 2 | 39,598,404 | Neuroprotective Potential of Glycyrrhizic Acid in Ischemic Stroke: Mechanisms and Therapeutic Prospects. | Pharmaceuticals (Basel) | 2024 | https://conductscience.org/library/papers/39598404 | PubMed |
| 3 | 20,598,162 | Overexpression of candidate tumor suppressor ECRG4 inhibits glioma proliferation and invasion. | J Exp Clin Cancer Res | 2010 | https://conductscience.org/library/papers/20598162 | PubMed |
| 4 | 17,462,578 | Glycyrrhizin binds to high-mobility group box 1 protein and inhibits its cytokine activities. | Chem Biol | 2007 | https://conductscience.org/library/papers/17462578 | PubMed |
| 5 | 22,128,119 | Triterpene functional genomics in licorice for identification of CYP72A154 involved in the biosynthesis of glycyrrhizin. | Plant Cell | 2011 | https://conductscience.org/library/papers/22128119 | PubMed |
| 6 | 21,644,799 | Glycyrrhizic acid and 18β-glycyrrhetinic acid modulate lipopolysaccharide-induced inflammatory response by suppression of NF-κB through PI3K p110δ and p110γ inhibitions. | J Agric Food Chem | 2011 | https://conductscience.org/library/papers/21644799 | PubMed |
| 7 | 24,162,829 | 18beta-glycyrrhetinic acid induces apoptosis in pituitary adenoma cells via ROS/MAPKs-mediated pathway. | J Neurooncol | 2014 | https://conductscience.org/library/papers/24162829 | PubMed |
| 8 | 24,220,159 | An overview on HMGB1 inhibitors as potential therapeutic agents in HMGB1-related pathologies. | Pharmacol Ther | 2014 | https://conductscience.org/library/papers/24220159 | PubMed |
| 9 | 23,457,494 | Glycyrrhizic acid suppresses the development of precancerous lesions via regulating the hyperproliferation, inflammation, angiogenesis and apoptosis in the colon of Wistar rats. | PLoS One | 2013 | https://conductscience.org/library/papers/23457494 | PubMed |
| 10 | 26,191,214 | Glycyrrhizic acid inhibits leukemia cell growth and migration via blocking AKT/mTOR/STAT3 signaling. | Int J Clin Exp Pathol | 2015 | https://conductscience.org/library/papers/26191214 | PubMed |
1 to 10 of 118
See all 118 referencesCited by7
The papers in our copy of PubMed whose reference list names this one, newest first. iCite, which reads more sources, counts 4 citations.
| PMID | Title | Journal | Year | In Papers | Source |
|---|---|---|---|---|---|
| 42,885,282 | Glycyrrhizic acid attenuates corneal inflammation and pathological angiogenesis through FAK/PI3K/AKT signaling. | Mol Med Rep | 2026 | https://conductscience.org/library/papers/42885282 | PubMed |
| 42,866,300 | Glycyrrhizic acid attenuates sepsis-induced acute lung injury by regulating macrophage M2 polarization via PRKCD. | J Thorac Dis | 2026 | https://conductscience.org/library/papers/42866300 | PubMed |
| 42,653,402 | Glycyrrhizin Ameliorates Learning and Memory Impairment via Inhibition of Neuroinflammation in an Alzheimer's Disease Mouse Model SAMP8. | Int J Mol Sci | 2026 | https://conductscience.org/library/papers/42653402 | PubMed |
| 42,588,111 | Betulin Alleviates 5-Fluorouracil-Induced Intestinal Mucositis in Mice. | Nutrients | 2026 | https://conductscience.org/library/papers/42588111 | PubMed |
| 42,440,570 | Glycyrrhizin (GLY) and glycyrrhetinic acid (GA) as potential multi-target antimicrobials: mechanisms, biofilm disruption, and synergy against drug-resistant pathogens. | Front Microbiol | 2026 | https://conductscience.org/library/papers/42440570 | PubMed |
| 42,298,622 | Dietary glycyrrhizic acid improves growth performance and modulates upper respiratory microbiota in weaned piglets. | BMC Vet Res | 2026 | https://conductscience.org/library/papers/42298622 | PubMed |
| 42,123,730 | Therapeutic Effects of Glycyrrhizic Acid on Dry Eye Disease: Targeting Pyroptosis, Oxidative Stress, and Epithelial Barrier Dysfunction. | Int J Mol Sci | 2026 | https://conductscience.org/library/papers/42123730 | PubMed |
Genes2
The genes the Gene search release ties to the paper: Swiss-Prot's references first, then PubTator's text mining.
| Gene | NCBI Gene ID | Linked by | In Genes | Source |
|---|---|---|---|---|
| HMGB1 | 3,146 | PubTator's text mining | https://conductscience.org/library/genes/3146 | NCBI Gene |
| PTK2B | 2,185 | PubTator's text mining | https://conductscience.org/library/genes/2185 | NCBI Gene |
Drugs0
The drugs whose trials, in the Pipelines release, list the paper.
None in this release.
Data0
The data bank entries PubMed's record names. Trial numbers are under Trials.
None in this release.
Data dates
The date of each source this release read.
- Trials
- 2026-11-12
- Gene search
- 2026-11-11
- Pipelines
- 2026-09-18
Sources 11
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- HGNCCC0
- iCiteCC BY 4.0
- NCBI GenePublic domain (US government)
- NIH RePORTER's grant and paper linksPublic domain
- Open TargetsCC0 1.0
- PMC's ID filePublic domain (US government)
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- HGNCCC0: https://www.genenames.org/about/license/
- iCiteCC BY 4.0
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH RePORTER's grant and paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PMC's ID fileNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
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