Paper · 42100296

Reward Deficiency Syndrome (RDS): A Common Neurogenetic Trait/State of All Addictions: Is this the new DSM?

Blum K and 24 others. Br J Healthc Med Res, 2026. Cited by 0 papers, by iCite.

11 sourcespapers-2026-11-12-0.1.0

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ConductScience Library. Reward Deficiency Syndrome (RDS): A Common Neurogenetic Trait/State of All Addictions: Is this the new DSM? Papers, record 42100296. Release papers-2026-11-12-0.1.0, 12 Nov 2026. https://conductscience.org/library/papers/42100296

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Paper

PubMed's record of the paper, with iCite's citation figures. No abstract is shown.

Title: Reward Deficiency Syndrome (RDS): A Common Neurogenetic Trait/State of All Addictions: Is this the new DSM?; PubMed
Journal: Br J Healthc Med Res; PubMed
Year: 2026; PubMed
Publication types: Journal Article; PubMed
PubMed: https://pubmed.ncbi.nlm.nih.gov/42100296/; PubMed
DOI: https://doi.org/10.14738/bjhr.1301.19797; PubMed
PMC: https://pmc.ncbi.nlm.nih.gov/articles/PMC13143636/; PubMed
The journal: https://conductscience.org/library/journal-index/9919258216406676; PubMed
Citations, by iCite: 0; iCite
Revised in PubMed: 2026-09-22; PubMed

Authors25

The authors in the order PubMed's record lists them, with the ORCID iDs it states.

Order	Author	Forename
1	Blum K	Kenneth
2	Lewandrowski KU	Kai Uwe
3	Lorio MP	Morgan P
4	Pinhasov A	Albert
5	Mohankumar K	Kavya
6	Sharafshah A	Alireza
7	Thanos PK	Panayotis K
8	Bowirrat A	Abdalla
9	Lindeau M	Marco
10	Dowling Á	Álvaro

1 to 10 of 25Source PubMed

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Topics0

NLM's MeSH indexing of the paper, its major topics first.

None in this release.

Grants4

Each grant PubMed's record writes, matched to the NIH project NIH's grant and paper links name for this paper, and each of those links the record does not write.

Grant, as the record writes it	Agency	Country	NIH project	Stated by	Source
I01 CX000479	CSRD VA	United States	I01CX000479	PubMed	NIH RePORTER
R21 DA045640	NIDA NIH HHS	United States	R21DA045640	PubMed	NIH RePORTER
R33 DA045640	NIDA NIH HHS	United States	R33DA045640	PubMed	NIH RePORTER
R41 MD012318	NIMHD NIH HHS	United States	R41MD012318	PubMed	NIH RePORTER

Trials0

The trials whose ClinicalTrials.gov record lists the paper, and the trial numbers the paper's PubMed record names.

None in this release.

Comments and corrections0

PubMed's comments and corrections, NLM's own indexing: retractions first, then expressions of concern, errata and updates, and comments last.

None in this release.

References123

The papers the reference list in PubMed's record names, those in our copy of PubMed, in the list's order.

Order	PMID	Title	Journal	Year	In Papers	Source
1	30,198,022	The Benefits of Genetic Addiction Risk Score (GARS™) Testing in Substance Use Disorder (SUD).	Int J Genom Data Min	2018	https://conductscience.org/library/papers/30198022	PubMed
2	25,377,988	The Gateway Hypothesis of substance abuse: developmental, biological and societal perspectives.	Acta Paediatr	2015	https://conductscience.org/library/papers/25377988	PubMed
3	26,306,329	The Molecular Neurobiology of Twelve Steps Program & Fellowship: Connecting the Dots for Recovery.	J Reward Defic Syndr	2015	https://conductscience.org/library/papers/26306329	PubMed
4	27,174,576	Common Neurogenetic Diagnosis and Meso-Limbic Manipulation of Hypodopaminergic Function in Reward Deficiency Syndrome (RDS): Changing the Recovery Landscape.	Curr Neuropharmacol	2017	https://conductscience.org/library/papers/27174576	PubMed
5	14,594,742	The serotonin system and spiritual experiences.	Am J Psychiatry	2003	https://conductscience.org/library/papers/14594742	PubMed
6	27,840,857	Fifty Years in the Development of a Glutaminergic-Dopaminergic Optimization Complex (KB220) to Balance Brain Reward Circuitry in Reward Deficiency Syndrome: A Pictorial.	Austin Addict Sci	2016	https://conductscience.org/library/papers/27840857	PubMed
7	27,814,639	Dopamine homeostasis: brain functional connectivity in reward deficiency syndrome.	Front Biosci (Landmark Ed)	2017	https://conductscience.org/library/papers/27814639	PubMed
8	26,052,556	NIDA-Drug Addiction Treatment Outcome Study (DATOS) Relapse as a Function of Spirituality/Religiosity.	J Reward Defic Syndr	2015	https://conductscience.org/library/papers/26052556	PubMed
9	28,033,474	Hypothesizing That Neuropharmacological and Neuroimaging Studies of Glutaminergic-Dopaminergic Optimization Complex (KB220Z) Are Associated With "Dopamine Homeostasis" in Reward Deficiency Syndrome (RDS).	Subst Use Misuse	2017	https://conductscience.org/library/papers/28033474	PubMed
10	4,631,379	A possible relationship between the pineal gland and ethanol preference in the rat.	Curr Ther Res Clin Exp	1973	https://conductscience.org/library/papers/4631379	PubMed

1 to 10 of 123

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Cited by0

The papers in our copy of PubMed whose reference list names this one, newest first. iCite, which reads more sources, counts 0 citations.

None in this release.

Genes2

The genes the Gene search release ties to the paper: Swiss-Prot's references first, then PubTator's text mining.

Gene	NCBI Gene ID	Linked by	In Genes	Source
COMT	1,312	PubTator's text mining	https://conductscience.org/library/genes/1312	NCBI Gene
DRD2	1,813	PubTator's text mining	https://conductscience.org/library/genes/1813	NCBI Gene

Drugs0

The drugs whose trials, in the Pipelines release, list the paper.

None in this release.

Data0

The data bank entries PubMed's record names. Trial numbers are under Trials.

None in this release.

Data dates

The date of each source this release read.

PubMed: 2026-11-06; PubMed
iCite: 2026-11-05; iCite
PMC's ID file: 2026-11-05; PMC's ID file
NIH RePORTER's grant and paper links: 2026-11-01; NIH RePORTER's grant and paper links
Trials: 2026-11-12
Gene search: 2026-11-11
Pipelines: 2026-09-18

Sources 11

ChEMBL, through Open TargetsCC BY-SA 3.0
ClinicalTrials.govNo license stated
HGNCCC0
iCiteCC BY 4.0
NCBI GenePublic domain (US government)
NIH RePORTER's grant and paper linksPublic domain
Open TargetsCC0 1.0
PMC's ID filePublic domain (US government)
PubMedNLM's terms
PubTator 3Public domain
UniProtCC BY 4.0

Each source's terms

ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
ClinicalTrials.govnone stated
HGNCCC0: https://www.genenames.org/about/license/
iCiteCC BY 4.0
NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
NIH RePORTER's grant and paper linksPublic domain (NIH RePORTER)
Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
PMC's ID fileNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
PubMedNLM's terms
PubTator 3Public domain
UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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