Paper · 42928367
The memory of the tumor microenvironment: epigenetic scarring and the hysteretic logic of therapeutic relapse.
Kokkanti RR and 4 others. Oncogene, 2026.
11 sourcespapers-2026-11-12-0.1.0
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ConductScience Library. The memory of the tumor microenvironment: epigenetic scarring and the hysteretic logic of therapeutic relapse. Papers, record 42928367. Release papers-2026-11-12-0.1.0, 12 Nov 2026. https://conductscience.org/library/papers/42928367
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Paper
PubMed's record of the paper, with iCite's citation figures. No abstract is shown.
- Title
- The memory of the tumor microenvironment: epigenetic scarring and the hysteretic logic of therapeutic relapse.
- Journal
- Oncogene
- Year
- 2026
- Publication types
- Journal Article, Review
- Revised in PubMed
- 2026-11-05
Source PubMed
Topics7
NLM's MeSH indexing of the paper, its major topics first.
| MeSH term | Major |
|---|---|
| Tumor Microenvironment | Major topic |
| Neoplasms | Major topic |
| Epigenesis, Genetic | Major topic |
| Neoplasm Recurrence, Local | Major topic |
| Humans | |
| Animals | |
| Extracellular Matrix |
Source PubMed
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Trials0
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Comments and corrections0
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References133
The papers the reference list in PubMed's record names, those in our copy of PubMed, in the list's order.
| Order | PMID | Title | Journal | Year | In Papers | Source |
|---|---|---|---|---|---|---|
| 1 | 27,912,061 | Tumor Interferon Signaling Regulates a Multigenic Resistance Program to Immune Checkpoint Blockade. | Cell | 2016 | https://conductscience.org/library/papers/27912061 | PubMed |
| 2 | 26,912,859 | Dynamics of epigenetic regulation at the single-cell level. | Science | 2016 | https://conductscience.org/library/papers/26912859 | PubMed |
| 3 | 19,931,152 | Matrix crosslinking forces tumor progression by enhancing integrin signaling. | Cell | 2009 | https://conductscience.org/library/papers/19931152 | PubMed |
| 4 | 16,397,526 | Histone deacetylase inhibitors and the promise of epigenetic (and more) treatments for cancer. | Nat Rev Cancer | 2006 | https://conductscience.org/library/papers/16397526 | PubMed |
| 5 | 17,538,624 | Gene-specific control of inflammation by TLR-induced chromatin modifications. | Nature | 2007 | https://conductscience.org/library/papers/17538624 | PubMed |
| 6 | 23,999,443 | Targeting lactate metabolism for cancer therapeutics. | J Clin Invest | 2013 | https://conductscience.org/library/papers/23999443 | PubMed |
| 7 | 40,499,006 | Epigenetic Heritability of Cell Plasticity Drives Cancer Drug Resistance through a One-to-Many Genotype-to-Phenotype Paradigm. | Cancer Res | 2025 | https://conductscience.org/library/papers/40499006 | PubMed |
| 8 | 17,957,189 | Models, mechanisms and clinical evidence for cancer dormancy. | Nat Rev Cancer | 2007 | https://conductscience.org/library/papers/17957189 | PubMed |
| 9 | 39,433,569 | Cancer treatment monitoring using cell-free DNA fragmentomes. | Nat Commun | 2024 | https://conductscience.org/library/papers/39433569 | PubMed |
| 10 | 33,879,235 | Advances in epigenetic therapeutics with focus on solid tumors. | Clin Epigenetics | 2021 | https://conductscience.org/library/papers/33879235 | PubMed |
1 to 10 of 133
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Data0
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Data dates
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- Trials
- 2026-11-12
- Gene search
- 2026-11-11
- Pipelines
- 2026-09-18
Sources 11
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- HGNCCC0
- iCiteCC BY 4.0
- NCBI GenePublic domain (US government)
- NIH RePORTER's grant and paper linksPublic domain
- Open TargetsCC0 1.0
- PMC's ID filePublic domain (US government)
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- HGNCCC0: https://www.genenames.org/about/license/
- iCiteCC BY 4.0
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH RePORTER's grant and paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PMC's ID fileNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
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