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Paper448118

Characterization of lymphocyte-activating factor (LAF) produced by human mononuclear cells: biochemical relationship of high and low molecular weight forms of LAF.

Togawa A and 2 others. J Immunol, 1979. Cited by 114 papers, by iCite.

11 sourcespapers-2026-11-12-0.1.0

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ConductScience Library. Characterization of lymphocyte-activating factor (LAF) produced by human mononuclear cells: biochemical relationship of high and low molecular weight forms of LAF. Papers, record 448118. Release papers-2026-11-12-0.1.0, 12 Nov 2026. https://conductscience.org/library/papers/448118

Paper

PubMed's record of the paper, with iCite's citation figures. No abstract is shown.

Title
Characterization of lymphocyte-activating factor (LAF) produced by human mononuclear cells: biochemical relationship of high and low molecular weight forms of LAF.
PubMed
Journal
J Immunol
PubMed
Year
1979
PubMed
Publication types
Journal Article
PubMed
Citations, by iCite
114
iCite
Relative citation ratio, by iCite
3.08
iCite
Revised in PubMed
2018-11-30
PubMed

Authors3

The authors in the order PubMed's record lists them, with the ORCID iDs it states.

OrderAuthorForenameKindORCID iD
1Togawa AA
2Oppenheim JJJ J
3Mizel SBS B

Source PubMed

Topics11

NLM's MeSH indexing of the paper, its major topics first.

MeSH termMajor
LymphocytesMajor topic
MonocytesMajor topic
Cell Adhesion
Chromatography
Chromatography, DEAE-Cellulose
Chromatography, Gel
Dose-Response Relationship, Immunologic
Humans
Hydroxyapatites
Mitogens
Molecular Weight

Source PubMed

Cited by18

The papers in our copy of PubMed whose reference list names this one, newest first. iCite, which reads more sources, counts 114 citations.

PMIDTitleJournalYearIn PapersSource
22,628,464Modelling the interaction of keratinocytes and fibroblasts during normal and abnormal wound healing processes.Proc Biol Sci2012https://conductscience.org/library/papers/22628464PubMed
8,228,811CD28-induced costimulation of T helper type 2 cells mediated by induction of responsiveness to interleukin 4.J Exp Med1993https://conductscience.org/library/papers/8228811PubMed
7,390,612Human macrophage activation factors. I. Multiple molecular species of MAF produced by a human lymphoid cell line.Inflammation1980https://conductscience.org/library/papers/7390612PubMed
7,014,447Human alveolar macrophages: effects of endotoxin in vitro.Infect Immun1980https://conductscience.org/library/papers/7014447PubMed
6,997,424Macrophage heterogeneity in man. A subpopulation of HLA-DR-bearing macrophages required for antigen-induced T cell activation also contains stimulators for autologous-reactive T cells.J Exp Med1980https://conductscience.org/library/papers/6997424PubMed
6,972,041Specific receptors for phorbol esters in lymphoid cell populations: role in enhanced production of T-cell growth factor.Proc Natl Acad Sci U S A1981https://conductscience.org/library/papers/6972041PubMed
6,787,168Effect of interleukin 1 on human thymocytes and purified human T cells.J Exp Med1981https://conductscience.org/library/papers/6787168PubMed
6,611,312Demonstration of interleukin 1 activity in apparently homogeneous specimens of the pI 5 form of rabbit endogenous pyrogen.Infect Immun1984https://conductscience.org/library/papers/6611312PubMed
6,351,073Leukemia cell lines can replace monocytes for mitogen-induced T-lymphocyte responses: this accessory function is dependent upon their differentiation stage.Proc Natl Acad Sci U S A1983https://conductscience.org/library/papers/6351073PubMed
6,325,504Silica-stimulated monocytes release fibroblast proliferation factors identical to interleukin 1. A potential role for interleukin 1 in the pathogenesis of silicosis.J Clin Invest1984https://conductscience.org/library/papers/6325504PubMed
4,055,031Identification of precursor of phagocytosis-stimulating factor in guinea pig polymorphonuclear neutrophils.Infect Immun1985https://conductscience.org/library/papers/4055031PubMed
3,876,178Modulation of the human immune response by the non-toxic and non-pyrogenic adjuvant aluminium hydroxide: effect on antigen uptake and antigen presentation.Clin Exp Immunol1985https://conductscience.org/library/papers/3876178PubMed
3,871,836Human interleukin 1. Purification to homogeneity.J Exp Med1985https://conductscience.org/library/papers/3871836PubMed
3,320,015Biosynthesis of the third component of complement in rat liver epithelial cell lines and its stimulation by effector molecules from cultured human mononuclear cells.In Vitro Cell Dev Biol1987https://conductscience.org/library/papers/3320015PubMed
3,264,804Existence of both IL-1 alpha and beta in normal human amniotic fluid: unique high molecular weight form of IL-1 beta.Immunology1988https://conductscience.org/library/papers/3264804PubMed
3,264,774Defective interleukin-1 production in a familial monocyte disorder with a combined abnormality of mobility and phagocytosis-killing.Clin Exp Immunol1988https://conductscience.org/library/papers/3264774PubMed
3,258,127Direct evidence for granuloma-inducing activity of interleukin-1. Induction of experimental pulmonary granuloma formation in mice by interleukin-1-coupled beads.Am J Pathol1988https://conductscience.org/library/papers/3258127PubMed
2,409,005Alpha 2-macroglobulin secretion enhanced in rat hepatocytes by partially characterized factor from Kupffer cells.Inflammation1985https://conductscience.org/library/papers/2409005PubMed

Data dates

The date of each source this release read.

PubMed
2026-11-06
PubMed
iCite
2026-11-05
iCite
PMC's ID file
2026-11-05
PMC's ID file
NIH RePORTER's grant and paper links
2026-11-01
NIH RePORTER's grant and paper links
Trials
2026-11-12
Gene search
2026-11-11
Pipelines
2026-09-18

None in this release

  • Grants
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  • Comments and corrections
  • References
  • Genes
  • Drugs
  • Data

Sources 11

  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • HGNCCC0
  • iCiteCC BY 4.0
  • NCBI GenePublic domain (US government)
  • NIH RePORTER's grant and paper linksPublic domain
  • Open TargetsCC0 1.0
  • PMC's ID filePublic domain (US government)
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • HGNCCC0: https://www.genenames.org/about/license/
  • iCiteCC BY 4.0
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH RePORTER's grant and paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PMC's ID fileNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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