Paper6325504
Silica-stimulated monocytes release fibroblast proliferation factors identical to interleukin 1. A potential role for interleukin 1 in the pathogenesis of silicosis.
Schmidt JA and 4 others. J Clin Invest, 1984. Cited by 261 papers, by iCite.
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ConductScience Library. Silica-stimulated monocytes release fibroblast proliferation factors identical to interleukin 1. A potential role for interleukin 1 in the pathogenesis of silicosis. Papers, record 6325504. Release papers-2026-11-12-0.1.0, 12 Nov 2026. https://conductscience.org/library/papers/6325504
Paper
PubMed's record of the paper, with iCite's citation figures. No abstract is shown.
- Title
- Silica-stimulated monocytes release fibroblast proliferation factors identical to interleukin 1. A potential role for interleukin 1 in the pathogenesis of silicosis.
- PubMed
Topics11
NLM's MeSH indexing of the paper, its major topics first.
| MeSH term | Major |
|---|---|
| Dust | Major topic |
| Interleukin-1 | Major topic |
| Monocytes | Major topic |
| Silicon Dioxide | Major topic |
| Silicosis | Major topic |
| Cells, Cultured | |
| Fibroblasts | |
| Humans | |
| Macrophages | |
| Minerals | |
| Peptide Hydrolases |
Source PubMed
References38
The papers the reference list in PubMed's record names, those in our copy of PubMed, in the list's order.
| Order | PMID | Title | Journal | Year | In Papers | Source |
|---|---|---|---|---|---|---|
| 1 | 4,288,309 | An examination of the cytotoxic effects of silica on macrophages. | J Exp Med | 1966 | https://conductscience.org/library/papers/4288309 | PubMed |
| 2 | 4,291,779 | Activity of a macrophage factor in collagen formation by silica. | Nature | 1967 | https://conductscience.org/library/papers/4291779 | PubMed |
| 3 | 4,352,592 | The in-vitro effects of silica-treated hamster macrophages on collagen production by hamster fibroblasts. | J Pathol | 1973 | https://conductscience.org/library/papers/4352592 | PubMed |
| 4 | 178,257 | Silicosis. | Am Rev Respir Dis | 1976 | https://conductscience.org/library/papers/178257 | PubMed |
| 5 | 932,208 | Lymphokine stimulation of collagen accumulation. | J Clin Invest | 1976 | https://conductscience.org/library/papers/932208 | PubMed |
| 6 | 961,824 | A macrophage-dependent factor that stimulates the proliferation of fibroblasts in vitro. | Am J Pathol | 1976 | https://conductscience.org/library/papers/961824 | PubMed |
| 7 | 825,607 | The chemotactic attraction of human fibroblasts to a lymphocyte-derived factor. | J Exp Med | 1976 | https://conductscience.org/library/papers/825607 | PubMed |
| 8 | 300,751 | Purification and properties of human lymphocyte activating factor (LAF). | J Immunol | 1977 | https://conductscience.org/library/papers/300751 | PubMed |
| 9 | 301,539 | Association of a low molecular weight helper factor(s) with thymocyte proliferative activity. | J Immunol | 1977 | https://conductscience.org/library/papers/301539 | PubMed |
| 10 | 915,290 | Partial purification of human lymphocyte-activating factor (LAF) by ultrafiltration and electrophoretic techniques. | J Immunol | 1977 | https://conductscience.org/library/papers/915290 | PubMed |
| 11 | 22,079 | Human leukocytic pyrogen: purification and development of a radioimmunoassay. | Proc Natl Acad Sci U S A | 1977 | https://conductscience.org/library/papers/22079 | PubMed |
| 12 | 655,375 | Refinement of the coomassie blue method of protein quantitation. A simple and linear spectrophotometric assay for less than or equal to 0.5 to 50 microgram of protein. | Anal Biochem | 1978 | https://conductscience.org/library/papers/655375 | PubMed |
| 13 | 705,337 | Hepatic fibrosis in schistosomiasis: egg granulomas secrete fibroblast stimulating factor in vitro. | Science | 1978 | https://conductscience.org/library/papers/705337 | PubMed |
| 14 | 312,500 | Dual control of cell growth by somatomedins and platelet-derived growth factor. | Proc Natl Acad Sci U S A | 1979 | https://conductscience.org/library/papers/312500 | PubMed |
| 15 | 448,118 | Characterization of lymphocyte-activating factor (LAF) produced by human mononuclear cells: biochemical relationship of high and low molecular weight forms of LAF. | J Immunol | 1979 | https://conductscience.org/library/papers/448118 | PubMed |
| 16 | 221,582 | Macrophage activation by mycobacterial water soluble compounds and synthetic muramyl dipeptide. | J Immunol | 1979 | https://conductscience.org/library/papers/221582 | PubMed |
| 17 | 479,763 | Detection of a mediator derived from endotoxin-stimulated macrohpages that induces the acute phase serum amyloid A response in mice. | J Exp Med | 1979 | https://conductscience.org/library/papers/479763 | PubMed |
| 18 | 6,965,973 | Endogenous pyrogens made by rabbit peritoneal exudate cells are identical with lymphocyte-activating factors made by rabbit alveolar macrophages. | J Immunol | 1980 | https://conductscience.org/library/papers/6965973 | PubMed |
| 19 | 6,770,028 | The functional relationship of the interleukins. | J Exp Med | 1980 | https://conductscience.org/library/papers/6770028 | PubMed |
| 20 | 6,970,264 | Human monocyte stimulation of fibroblast growth by a soluble mediator(s). | J Reticuloendothel Soc | 1980 | https://conductscience.org/library/papers/6970264 | PubMed |
Cited by58
The papers in our copy of PubMed whose reference list names this one, newest first. iCite, which reads more sources, counts 261 citations.
| PMID | Title | Journal | Year | In Papers | Source |
|---|---|---|---|---|---|
| 38,397,476 | Circulating Biomarkers Involved in the Development of and Progression to Chronic Pancreatitis-A Literature Review. | Biomolecules | 2024 | https://conductscience.org/library/papers/38397476 | PubMed |
| 38,264,932 | Crosstalk between fibroblasts and immunocytes in fibrosis: From molecular mechanisms to clinical trials. | Clin Transl Med | 2024 | https://conductscience.org/library/papers/38264932 | PubMed |
| 36,672,608 | Biomonitoring Exposure and Early Diagnosis in Silicosis: A Comprehensive Review of the Current Literature. | Biomedicines | 2022 | https://conductscience.org/library/papers/36672608 | PubMed |
| 35,936,059 | High-fat Western diet consumption exacerbates silica-induced pulmonary inflammation and fibrosis. | Toxicol Rep | 2022 | https://conductscience.org/library/papers/35936059 | PubMed |
| 34,976,743 | High-fat western diet-consumption alters crystalline silica-induced serum adipokines, inflammatory cytokines and arterial blood flow in the F344 rat. | Toxicol Rep | 2022 | https://conductscience.org/library/papers/34976743 | PubMed |
| 33,854,771 | Occupational lung disease: A narrative review of lung conditions from the workplace. | Ann Med Surg (Lond) | 2021 | https://conductscience.org/library/papers/33854771 | PubMed |
| 23,087,690 | IL-1 family cytokines trigger sterile inflammatory disease. | Front Immunol | 2012 | https://conductscience.org/library/papers/23087690 | PubMed |
| 21,869,759 | Human monocytes accelerate proliferation and blunt differentiation of preadipocytes in association with suppression of C/EBPΑ mRNA. | Obesity (Silver Spring) | 2012 | https://conductscience.org/library/papers/21869759 | PubMed |
| 18,475,600 | Preface. | Mediators Inflamm | 1994 | https://conductscience.org/library/papers/18475600 | PubMed |
| 15,866,772 | Time course of gene expression of inflammatory mediators in rat lung after diesel exhaust particle exposure. | Environ Health Perspect | 2005 | https://conductscience.org/library/papers/15866772 | PubMed |
| 15,665,045 | Crystalline and amorphous silica differentially regulate the cyclooxygenase-prostaglandin pathway in pulmonary fibroblasts: implications for pulmonary fibrosis. | Am J Physiol Lung Cell Mol Physiol | 2005 | https://conductscience.org/library/papers/15665045 | PubMed |
| 15,300,233 | Acute lung injury after allogeneic stem cell transplantation: is the lung a target of acute graft-versus-host disease? | Bone Marrow Transplant | 2004 | https://conductscience.org/library/papers/15300233 | PubMed |
| 15,240,873 | IL-1beta: an endosomal exit. | Proc Natl Acad Sci U S A | 2004 | https://conductscience.org/library/papers/15240873 | PubMed |
| 12,162,437 | Cytokine polymorphisms in silicosis and other pneumoconioses. | Mol Cell Biochem | 2002 | https://conductscience.org/library/papers/12162437 | PubMed |
| 11,737,074 | Lymphopenia in occupational pulmonary silicosis with or without autoimmune disease. | Clin Exp Immunol | 2001 | https://conductscience.org/library/papers/11737074 | PubMed |
| 9,370,935 | Macrophage migration inhibitory factor induces phagocytosis of foreign particles by macrophages in autocrine and paracrine fashion. | Immunology | 1997 | https://conductscience.org/library/papers/9370935 | PubMed |
| 9,209,799 | ANCA-associated diseases and silica exposure. | Clin Rev Allergy Immunol | 1997 | https://conductscience.org/library/papers/9209799 | PubMed |
| 8,977,606 | T lymphocytes and silica-induced pulmonary inflammation and fibrosis in mice. | Thorax | 1996 | https://conductscience.org/library/papers/8977606 | PubMed |
| 8,394,065 | Multiple clinical and biological autoimmune manifestations in 50 workers after occupational exposure to silica. | Ann Rheum Dis | 1993 | https://conductscience.org/library/papers/8394065 | PubMed |
| 8,389,528 | Immunohistochemical localization of transforming growth factor-beta 1 in rats with experimental silicosis, alveolar type II hyperplasia, and lung cancer. | Am J Pathol | 1993 | https://conductscience.org/library/papers/8389528 | PubMed |
Genes1
The genes the Gene search release ties to the paper: Swiss-Prot's references first, then PubTator's text mining.
| Gene | NCBI Gene ID | Linked by | In Genes |
|---|---|---|---|
| IL1A | 3,552 | PubTator's text mining | https://conductscience.org/library/genes/3552 |
Source NCBI Gene
Data dates
The date of each source this release read.
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- 2026-11-12
- Gene search
- 2026-11-11
- Pipelines
- 2026-09-18
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- Comments and corrections
- Drugs
- Data
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- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- HGNCCC0
- iCiteCC BY 4.0
- NCBI GenePublic domain (US government)
- NIH RePORTER's grant and paper linksPublic domain
- Open TargetsCC0 1.0
- PMC's ID filePublic domain (US government)
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- HGNCCC0: https://www.genenames.org/about/license/
- iCiteCC BY 4.0
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH RePORTER's grant and paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PMC's ID fileNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
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