Paper · 5774112

Effects of secretin, pancreozymin, or gastrin on the response of the endocrine pancreas to administration of glucose or arginine in man.

Dupre J and 4 others. J Clin Invest, 1969. Cited by 213 papers, by iCite.

11 sourcespapers-2026-11-12-0.1.0

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ConductScience Library. Effects of secretin, pancreozymin, or gastrin on the response of the endocrine pancreas to administration of glucose or arginine in man. Papers, record 5774112. Release papers-2026-11-12-0.1.0, 12 Nov 2026. https://conductscience.org/library/papers/5774112

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Paper

PubMed's record of the paper, with iCite's citation figures. No abstract is shown.

Title: Effects of secretin, pancreozymin, or gastrin on the response of the endocrine pancreas to administration of glucose or arginine in man.; PubMed
Journal: J Clin Invest; PubMed
Year: 1969; PubMed
Publication types: Journal Article; PubMed
PubMed: https://pubmed.ncbi.nlm.nih.gov/5774112/; PubMed
DOI: https://doi.org/10.1172/jci106032; PubMed
PMC: https://pmc.ncbi.nlm.nih.gov/articles/PMC322279/; PubMed
The journal: https://conductscience.org/library/journal-index/7802877; PubMed
Citations, by iCite: 213; iCite
Revised in PubMed: 2018-12-17; PubMed

Authors5

The authors in the order PubMed's record lists them, with the ORCID iDs it states.

Order	Author	Forename
1	Dupre J	J
2	Curtis JD	J D
3	Unger RH	R H
4	Waddell RW	R W
5	Beck JC	J C

Source PubMed

Topics16

NLM's MeSH indexing of the paper, its major topics first.

MeSH term	Major
Arginine	Major topic
Cholecystokinin	Major topic
Gastrins	Major topic
Glucose	Major topic
Insulin	Major topic
Pancreas	Major topic
Secretin	Major topic
Adolescent
Adult
Female
Gastric Juice
Humans
Injections, Intravenous
Insulin Secretion
Intestine, Small
Male

Source PubMed

Grants0

Each grant PubMed's record writes, matched to the NIH project NIH's grant and paper links name for this paper, and each of those links the record does not write.

None in this release.

Trials0

The trials whose ClinicalTrials.gov record lists the paper, and the trial numbers the paper's PubMed record names.

None in this release.

Comments and corrections0

PubMed's comments and corrections, NLM's own indexing: retractions first, then expressions of concern, errata and updates, and comments last.

None in this release.

References25

The papers the reference list in PubMed's record names, those in our copy of PubMed, in the list's order.

Order	PMID	Title	Journal	Year	In Papers	Source
1	6,028,125	Individual variation in secretory capacity of gastric acid to stimulation with solid food and with histamine.	Clin Sci	1967	https://conductscience.org/library/papers/6028125	PubMed
2	6,074,000	Plasma insulin responses to oral and intravenous glucose: studies in normal and diabetic sujbjects.	J Clin Invest	1967	https://conductscience.org/library/papers/6074000	PubMed
3	6,025,482	Basal plasma glucagon levels of man.	J Clin Invest	1967	https://conductscience.org/library/papers/6025482	PubMed
4	6,024,527	Intestinal hormones and plasma insulin: an insulinotropic action of secretin.	Br Med J	1967	https://conductscience.org/library/papers/6024527	PubMed
5	5,337,153	Effects of adrenergic and cholinergic agents upon insulin secretion in vitro.	Endocrinology	1967	https://conductscience.org/library/papers/5337153	PubMed
6	4,290,022	The effects of secretin, pancreozymin, and gastrin on insulin and glucagon secretion in anesthetized dogs.	J Clin Invest	1967	https://conductscience.org/library/papers/4290022	PubMed
7	6,019,593	Stimulation of insulin secretion by pancreozymin.	Diabetes	1967	https://conductscience.org/library/papers/6019593	PubMed
8	5,912,065	Stimulation of release of insulin by an extract of intestinal mucosa.	Diabetes	1966	https://conductscience.org/library/papers/5912065	PubMed
9	5,220,948	Radioimmunoassayable glucagon levels in man: effects of starvation, hypoglycemia, and glucose administration.	Proc Natl Acad Sci U S A	1966	https://conductscience.org/library/papers/5220948	PubMed
10	4,161,054	Effects of secretin on insulin and glucagon in portal and peripheral blood in man.	Lancet	1966	https://conductscience.org/library/papers/4161054	PubMed

1 to 10 of 25

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Cited by42

The papers in our copy of PubMed whose reference list names this one, newest first. iCite, which reads more sources, counts 213 citations.

PMID	Title	Journal	Year	In Papers	Source
33,096,658	The Impact of Amino Acids on Postprandial Glucose and Insulin Kinetics in Humans: A Quantitative Overview.	Nutrients	2020	https://conductscience.org/library/papers/33096658	PubMed
31,853,211	Premises for Cholecystokinin and Gastrin Peptides in Diabetes Therapy.	Clin Med Insights Endocrinol Diabetes	2019	https://conductscience.org/library/papers/31853211	PubMed
22,886,351	Proton pump inhibitors: impact on glucose metabolism.	Endocrine	2013	https://conductscience.org/library/papers/22886351	PubMed
20,503,484	Secretin: Should we revisit its metabolic outcomes?	J Endocrinol Invest	2010	https://conductscience.org/library/papers/20503484	PubMed
16,879,785	Assessment of islet function following islet and pancreas transplantation.	Curr Diab Rep	2006	https://conductscience.org/library/papers/16879785	PubMed
8,689,907	Does Helicobacter pylori-induced gastritis enhance food-stimulated insulin release?	Dig Dis Sci	1996	https://conductscience.org/library/papers/8689907	PubMed
6,503,499	[Duodenum-sparing pancreas head resection in chronic pancreatitis--results after 10 years' use].	Langenbecks Arch Chir	1984	https://conductscience.org/library/papers/6503499	PubMed
5,780,193	The role of aminogenic glucagon secretion in blood glucose homeostasis.	J Clin Invest	1969	https://conductscience.org/library/papers/5780193	PubMed
5,548,559	Stimulation of insulin secretion by medium-chain triglycerides in patients with cirrhosis.	Gut	1971	https://conductscience.org/library/papers/5548559	PubMed
5,543,376	Reactions to acid in the intestine in health and disease.	Gut	1971	https://conductscience.org/library/papers/5543376	PubMed

1 to 10 of 42

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Genes4

The genes the Gene search release ties to the paper: Swiss-Prot's references first, then PubTator's text mining.

Gene	NCBI Gene ID	Linked by	In Genes	Source
GAST	2,520	PubTator's text mining	https://conductscience.org/library/genes/2520	NCBI Gene
GCG	2,641	PubTator's text mining	https://conductscience.org/library/genes/2641	NCBI Gene
INS	3,630	PubTator's text mining	https://conductscience.org/library/genes/3630	NCBI Gene
SCT	6,343	PubTator's text mining	https://conductscience.org/library/genes/6343	NCBI Gene

Drugs0

The drugs whose trials, in the Pipelines release, list the paper.

None in this release.

Data0

The data bank entries PubMed's record names. Trial numbers are under Trials.

None in this release.

Data dates

The date of each source this release read.

PubMed: 2026-11-06; PubMed
iCite: 2026-11-05; iCite
PMC's ID file: 2026-11-05; PMC's ID file
NIH RePORTER's grant and paper links: 2026-11-01; NIH RePORTER's grant and paper links
Trials: 2026-11-12
Gene search: 2026-11-11
Pipelines: 2026-09-18

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ChEMBL, through Open TargetsCC BY-SA 3.0
ClinicalTrials.govNo license stated
HGNCCC0
iCiteCC BY 4.0
NCBI GenePublic domain (US government)
NIH RePORTER's grant and paper linksPublic domain
Open TargetsCC0 1.0
PMC's ID filePublic domain (US government)
PubMedNLM's terms
PubTator 3Public domain
UniProtCC BY 4.0

Each source's terms

ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
ClinicalTrials.govnone stated
HGNCCC0: https://www.genenames.org/about/license/
iCiteCC BY 4.0
NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
NIH RePORTER's grant and paper linksPublic domain (NIH RePORTER)
Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
PMC's ID fileNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
PubMedNLM's terms
PubTator 3Public domain
UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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