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Paper · 58834

Antigen-non-specific T-cell factor in B-cell activation. Origin, biological properties and failure to show a relationship to H-2.

Waldmann H and 2 others. Immunology, 1976. Cited by 40 papers, by iCite.

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ConductScience Library. Antigen-non-specific T-cell factor in B-cell activation. Origin, biological properties and failure to show a relationship to H-2. Papers, record 58834. Release papers-2026-11-12-0.1.0, 12 Nov 2026. https://conductscience.org/library/papers/58834

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Paper

PubMed's record of the paper, with iCite's citation figures. No abstract is shown.

Title
Antigen-non-specific T-cell factor in B-cell activation. Origin, biological properties and failure to show a relationship to H-2.
PubMed
Journal
Immunology
PubMed
Year
1976
PubMed
Publication types
Journal Article
PubMed
Citations, by iCite
40
iCite
Relative citation ratio, by iCite
0.91
iCite
Revised in PubMed
2018-11-13
PubMed

Authors3

The authors in the order PubMed's record lists them, with the ORCID iDs it states.

OrderAuthorForenameKindORCID iD
1Waldmann HH
2Poulton PP
3Desaymard CC

Source PubMed

Topics15

NLM's MeSH indexing of the paper, its major topics first.

MeSH termMajor
B-LymphocytesMajor topic
EpitopesMajor topic
T-LymphocytesMajor topic
Animals
Clone Cells
Concanavalin A
Erythrocytes
Histocompatibility Antigens
Lymphocyte Activation
Macrophages
Mice
Mice, Inbred BALB C
Mice, Nude
Mitosis
Species Specificity

Source PubMed

Grants0

Each grant PubMed's record writes, matched to the NIH project NIH's grant and paper links name for this paper, and each of those links the record does not write.

None in this release.

Trials0

The trials whose ClinicalTrials.gov record lists the paper, and the trial numbers the paper's PubMed record names.

None in this release.

Comments and corrections0

PubMed's comments and corrections, NLM's own indexing: retractions first, then expressions of concern, errata and updates, and comments last.

None in this release.

References13

The papers the reference list in PubMed's record names, those in our copy of PubMed, in the list's order.

OrderPMIDTitleJournalYearIn PapersSource
14,610,054Separation of mouse spleen cells by passage through columns of sephadex G-10.J Immunol Methods1974https://conductscience.org/library/papers/4610054PubMed
24,610,078Antigen-specific T-cell factor in cell cooperation: physical properties and mapping in the left-hand (K) half of H-2.J Exp Med1974https://conductscience.org/library/papers/4610078PubMed
351,901Collaboration of histoincompatible T and B lymphocytes using cells from tetraparental bone marrow chimeras.J Exp Med1975https://conductscience.org/library/papers/51901PubMed
45,718,505Differential effects of human granulocytes and lymphocytes on human fibroblasts in vitro.Clin Exp Immunol1968https://conductscience.org/library/papers/5718505PubMed
51,082,098Cooperation across the histocompatibility barrier.Nature1975https://conductscience.org/library/papers/1082098PubMed
61,092,612T cell-dependent mediator in the immune response. III. The role of non-specific factor (NSF) in the in vitro immune response.Immunology1975https://conductscience.org/library/papers/1092612PubMed
71,093,041Adult thymectomy results in loss of T-dependent mitogen response in mouse spleen cells.Nature1975https://conductscience.org/library/papers/1093041PubMed
81,093,973T cell-dependent mediator and B-cell clones.Immunology1975https://conductscience.org/library/papers/1093973PubMed
94,132,599Editorial: Immune activation of B cells: evidence for 'one nonspecific triggering signal' not delivered by the Ig receptors.Scand J Immunol1974https://conductscience.org/library/papers/4132599PubMed
104,545,893Activation of T and B lymphocytes in vitro. II. Biological and biochemical properties of an allogeneic effect factor (AEF) active in triggering specific B lymphocytes.J Exp Med1974https://conductscience.org/library/papers/4545893PubMed

Cited by12

The papers in our copy of PubMed whose reference list names this one, newest first. iCite, which reads more sources, counts 40 citations.

PMIDTitleJournalYearIn PapersSource
6,975,350Analysis of the response of B cells from CBA/N-defective mice to nonspecific T cell help.J Exp Med1981https://conductscience.org/library/papers/6975350PubMed
6,950,432Specific cellular stimulation in the primary immune response: experimental test of a quantized model.Proc Natl Acad Sci U S A1982https://conductscience.org/library/papers/6950432PubMed
6,792,725How many T cells help one B cell?Springer Semin Immunopathol1980https://conductscience.org/library/papers/6792725PubMed
6,227,678Dendritic cells induce T lymphocytes to release B cell-stimulating factors by an interleukin 2-dependent mechanism.J Exp Med1983https://conductscience.org/library/papers/6227678PubMed
6,195,711Multiple thymus-derived helper cell activities involved in antibody responses.Surv Immunol Res1982https://conductscience.org/library/papers/6195711PubMed
800,405Restriction in the function of single helper T cells.Immunology1976https://conductscience.org/library/papers/800405PubMed
312,259The production of a soluble human T-lymphocyte derived factor which substitutes for helper T lymphocytes in the in vitro production of immunoglobulin.Immunology1979https://conductscience.org/library/papers/312259PubMed
306,408
Restricted helper function of F1 hybrid T cells positively selected to heterologous erythrocytes in irradiated parental strain mice. II. Evidence for restrictions affecting helper cell induction and T-B collaboration, both mapping to the K-end of the H-2 complex.
J Exp Med1978https://conductscience.org/library/papers/306408PubMed
301,854Heterogeneity of B cells reacting with T-cell factors. Evidence for matching T-cell and B-cell subsets.Immunology1977https://conductscience.org/library/papers/301854PubMed
301,172The specificity of T-cell helper factor in man.J Exp Med1977https://conductscience.org/library/papers/301172PubMed

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Genes0

The genes the Gene search release ties to the paper: Swiss-Prot's references first, then PubTator's text mining.

None in this release.

Drugs0

The drugs whose trials, in the Pipelines release, list the paper.

None in this release.

Data0

The data bank entries PubMed's record names. Trial numbers are under Trials.

None in this release.

Data dates

The date of each source this release read.

PubMed
2026-11-06
PubMed
iCite
2026-11-05
iCite
PMC's ID file
2026-11-05
PMC's ID file
NIH RePORTER's grant and paper links
2026-11-01
NIH RePORTER's grant and paper links
Trials
2026-11-12
Gene search
2026-11-11
Pipelines
2026-09-18

Sources 11

  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • HGNCCC0
  • iCiteCC BY 4.0
  • NCBI GenePublic domain (US government)
  • NIH RePORTER's grant and paper linksPublic domain
  • Open TargetsCC0 1.0
  • PMC's ID filePublic domain (US government)
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • HGNCCC0: https://www.genenames.org/about/license/
  • iCiteCC BY 4.0
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH RePORTER's grant and paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PMC's ID fileNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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