Paper · 6141562

Operational models of pharmacological agonism.

Black JW and 1 other. Proc R Soc Lond B Biol Sci, 1983. Cited by 930 papers, by iCite.

11 sourcespapers-2026-11-12-0.1.0

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ConductScience Library. Operational models of pharmacological agonism. Papers, record 6141562. Release papers-2026-11-12-0.1.0, 12 Nov 2026. https://conductscience.org/library/papers/6141562

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Paper

PubMed's record of the paper, with iCite's citation figures. No abstract is shown.

Title: Operational models of pharmacological agonism.; PubMed
Journal: Proc R Soc Lond B Biol Sci; PubMed
Year: 1983; PubMed
Publication types: Comparative Study, Journal Article; PubMed
PubMed: https://pubmed.ncbi.nlm.nih.gov/6141562/; PubMed
DOI: https://doi.org/10.1098/rspb.1983.0093; PubMed
The journal: https://conductscience.org/library/journal-index/7505889; PubMed
Citations, by iCite: 930; iCite
Relative citation ratio, by iCite: 23.1; iCite
Revised in PubMed: 2018-12-12; PubMed

Authors2

The authors in the order PubMed's record lists them, with the ORCID iDs it states.

Order	Author	Forename	Kind	ORCID iD
1	Black JW	J W
2	Leff P	P

Source PubMed

Topics6

NLM's MeSH indexing of the paper, its major topics first.

MeSH term	Major
Models, Biological	Major topic
Pharmacology	Major topic
Receptors, Drug	Major topic
Kinetics
Pharmaceutical Preparations
Statistics as Topic

Source PubMed

Grants0

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None in this release.

Trials0

The trials whose ClinicalTrials.gov record lists the paper, and the trial numbers the paper's PubMed record names.

None in this release.

Comments and corrections0

PubMed's comments and corrections, NLM's own indexing: retractions first, then expressions of concern, errata and updates, and comments last.

None in this release.

References0

The papers the reference list in PubMed's record names, those in our copy of PubMed, in the list's order.

None in this release.

Cited by458

The papers in our copy of PubMed whose reference list names this one, newest first. iCite, which reads more sources, counts 930 citations.

PMID	Title	Journal	Year	In Papers	Source
42,829,478	Thermodynamic Basis of Paton's Rate Theory of Drug Action: Occupation Theory as Its Steady-State Limit.	Cureus	2026	https://conductscience.org/library/papers/42829478	PubMed
42,809,610	Spatiotemporal modeling of GPCR signaling: The role of endosomal dynamics and receptor recycling.	PLoS Comput Biol	2026	https://conductscience.org/library/papers/42809610	PubMed
42,754,591	Structure-based design of subtype-selective psychedelic analogs.	Nat Commun	2026	https://conductscience.org/library/papers/42754591	PubMed
42,662,529	Asymmetric cross-reactivity of nuclear receptors reveals an evolutionary buffer between estrogen and androgen signaling.	iScience	2026	https://conductscience.org/library/papers/42662529	PubMed
42,625,116	Side-Chain Homologs of Δ9-THC, Δ8-THC, and HHC Reveal Pathway Bias at CB1R and CB2R Cannabinoid Receptors.	Mol Neurobiol	2026	https://conductscience.org/library/papers/42625116	PubMed
42,614,837	Kinetic Benefit(s) of Allosteric Receptor Blockade by Positive Allosteric Modulator Antagonists.	ACS Pharmacol Transl Sci	2026	https://conductscience.org/library/papers/42614837	PubMed
42,601,409	New paradigm of q-CAR drug development targeting disease-specific protein conformations.	NPJ Drug Discov	2026	https://conductscience.org/library/papers/42601409	PubMed
42,473,300	In praise of the hyperbola.	J Exp Anal Behav	2026	https://conductscience.org/library/papers/42473300	PubMed
42,471,917	Two Routes to the Same Equation: Kinetic and Statistical-Thermodynamic Derivations of the Classical Drug-Receptor Occupancy Relationship.	Cureus	2026	https://conductscience.org/library/papers/42471917	PubMed
42,303,736	Potent and biased agonists of class B1 GPCRs from a heterochiral design strategy.	Nat Chem	2026	https://conductscience.org/library/papers/42303736	PubMed

1 to 10 of 458

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Genes0

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None in this release.

Drugs0

The drugs whose trials, in the Pipelines release, list the paper.

None in this release.

Data0

The data bank entries PubMed's record names. Trial numbers are under Trials.

None in this release.

Data dates

The date of each source this release read.

PubMed: 2026-11-06; PubMed
iCite: 2026-11-05; iCite
PMC's ID file: 2026-11-05; PMC's ID file
NIH RePORTER's grant and paper links: 2026-11-01; NIH RePORTER's grant and paper links
Trials: 2026-11-12
Gene search: 2026-11-11
Pipelines: 2026-09-18

Sources 11

ChEMBL, through Open TargetsCC BY-SA 3.0
ClinicalTrials.govNo license stated
HGNCCC0
iCiteCC BY 4.0
NCBI GenePublic domain (US government)
NIH RePORTER's grant and paper linksPublic domain
Open TargetsCC0 1.0
PMC's ID filePublic domain (US government)
PubMedNLM's terms
PubTator 3Public domain
UniProtCC BY 4.0

Each source's terms

ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
ClinicalTrials.govnone stated
HGNCCC0: https://www.genenames.org/about/license/
iCiteCC BY 4.0
NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
NIH RePORTER's grant and paper linksPublic domain (NIH RePORTER)
Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
PMC's ID fileNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
PubMedNLM's terms
PubTator 3Public domain
UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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