ConductScience.org, home
Papers
API referenceFor AI assistants

Paper64327

Inhibition of human lymphocyte transformation by human alpha-foetoprotein (HAFP); comparison of foetal and hepatoma HAFP and kinetic studies in vitro immunosuppression.

Yachnin S and 1 other. Clin Exp Immunol, 1976. Cited by 64 papers, by iCite.

11 sourcespapers-2026-11-12-0.1.0

Download JSON
Cite this record

ConductScience Library. Inhibition of human lymphocyte transformation by human alpha-foetoprotein (HAFP); comparison of foetal and hepatoma HAFP and kinetic studies in vitro immunosuppression. Papers, record 64327. Release papers-2026-11-12-0.1.0, 12 Nov 2026. https://conductscience.org/library/papers/64327

Paper

PubMed's record of the paper, with iCite's citation figures. No abstract is shown.

Title
Inhibition of human lymphocyte transformation by human alpha-foetoprotein (HAFP); comparison of foetal and hepatoma HAFP and kinetic studies in vitro immunosuppression.
PubMed
Journal
Clin Exp Immunol
PubMed
Year
1976
PubMed
Publication types
Comparative Study, Journal Article, Research Support, U.S. Gov't, P.H.S.
PubMed
Citations, by iCite
64
iCite
Relative citation ratio, by iCite
1.93
iCite
Revised in PubMed
2021-12-03
PubMed

Authors2

The authors in the order PubMed's record lists them, with the ORCID iDs it states.

OrderAuthorForenameKindORCID iD
1Yachnin SS
2Lester EE

Source PubMed

Topics14

NLM's MeSH indexing of the paper, its major topics first.

MeSH termMajor
Liver NeoplasmsMajor topic
Lymphocyte ActivationMajor topic
alpha-FetoproteinsMajor topic
Adult
Aged
Carcinoma, Hepatocellular
Fetus
Humans
Immunosuppression Therapy
Kinetics
Lectins
Liver
Middle Aged
Stomach Neoplasms

Source PubMed

References12

The papers the reference list in PubMed's record names, those in our copy of PubMed, in the list's order.

OrderPMIDTitleJournalYearIn PapersSource
14,110,991Inhibition of phytohemagglutinin-induced lymphocyte transformation by globulins; lack of correlation with phytohemagglutinin precipitation by serum proteins.J Immunol1972https://conductscience.org/library/papers/4110991PubMed
24,113,793The effect of immunoregulatory globulin (IRA) upon lymphocytes in vitro.J Immunol1972https://conductscience.org/library/papers/4113793PubMed
34,338,228Human -fetoprotein. Isolation, characterization, and demonstration of microheterogeneity.J Biol Chem1972https://conductscience.org/library/papers/4338228PubMed
44,353,382Developmental changes in microheterogeneity of foetal plasma glycoproteins of mice.Biochem J1973https://conductscience.org/library/papers/4353382PubMed
546,267Suppression of the immune response by alpha-fetoprotein on the primary and secondary antibody response.J Exp Med1975https://conductscience.org/library/papers/46267PubMed
646,911Fetuin, an inhibitor of lymphocyte transformation. The interaction of fetuin with phytomitogens and a possible role for fetuin in fetal development.J Exp Med1975https://conductscience.org/library/papers/46911PubMed
74,724,072Human chorionic gonadotropin: its possible role in maternal lymphocyte suppression.Science1973https://conductscience.org/library/papers/4724072PubMed
85,001,443[Identification and preliminary purification of the feto-protein binding the estrogens in the serum of newborn rats].C R Acad Hebd Seances Acad Sci D1971https://conductscience.org/library/papers/5001443PubMed
95,038,768
The potentiation and inhibition by autologous red cells and platelets of human lymphocyte transformation induced by pokeweed mitogen concanavalin A, mercuric chloride, antigen, and mixed leucocyte culture.
Clin Exp Immunol1972https://conductscience.org/library/papers/5038768PubMed
1050,564Binding of alpha-foetoprotein to murine T cells.Nature1975https://conductscience.org/library/papers/50564PubMed
115,257,125Purification of mitogenic proteins derived from Phaseolus vulgaris: isolation of potent and weak phytohemagglutinins possessing mitogenic activity.Proc Natl Acad Sci U S A1969https://conductscience.org/library/papers/5257125PubMed
1260,761Demonstration of the inhibitory effect of human alpha-fetoprotein on in vitro transformation of human lymphocytes.Proc Natl Acad Sci U S A1976https://conductscience.org/library/papers/60761PubMed

Cited by9

The papers in our copy of PubMed whose reference list names this one, newest first. iCite, which reads more sources, counts 64 citations.

PMIDTitleJournalYearIn PapersSource
7,389,211Are pregnancy-associated serum proteins responsible for the inhibition of lymphocyte transformation by pregnancy serum?Clin Exp Immunol1980https://conductscience.org/library/papers/7389211PubMed
6,172,344Inhibitory action of pig alpha-fetoprotein through early activated thymocyte surface Na+, K+-adenosinetriphosphatase.Folia Microbiol (Praha)1981https://conductscience.org/library/papers/6172344PubMed
6,158,053Inhibitory effect of alpha-fetoprotein on the binding of myasthenia gravis antibody to acetylcholine receptor.Proc Natl Acad Sci U S A1980https://conductscience.org/library/papers/6158053PubMed
90,571Lymphocyte response to phytohaemagglutinin in the presence of serum from pregnant women: correlation with serum levels of alpha-foetoprotein.Clin Exp Immunol1979https://conductscience.org/library/papers/90571PubMed
82,499Effects of human alpha-foetoprotein on human B and T lymphocyte proliferation in vitro.Clin Exp Immunol1978https://conductscience.org/library/papers/82499PubMed
81,256Cellular and genetic restrictions in the immunoregulatory activity of alpha-fetoprotein. II. Alpha-fetoprotein-induced suppression of cytotoxic T lymphocyte development.J Exp Med1978https://conductscience.org/library/papers/81256PubMed
75,940Cellular and genetic restrictions in the immunoregulatory activity of alpha-fetoprotein. I. Selective inhibition of anti-Ia-associated proliferative reactions.J Exp Med1978https://conductscience.org/library/papers/75940PubMed
75,181Inhibition of human lymphocyte transformation by human alpha-foetoprotein (HAFP): studies on the mode of HAFP action and the role of HAFP polymorphism.Immunology1978https://conductscience.org/library/papers/75181PubMed
71,737A postsynthetic modification of human alpha-fetoprotein controls its immunosuppressive potency.Proc Natl Acad Sci U S A1977https://conductscience.org/library/papers/71737PubMed

Data dates

The date of each source this release read.

PubMed
2026-11-06
PubMed
iCite
2026-11-05
iCite
PMC's ID file
2026-11-05
PMC's ID file
NIH RePORTER's grant and paper links
2026-11-01
NIH RePORTER's grant and paper links
Trials
2026-11-12
Gene search
2026-11-11
Pipelines
2026-09-18

None in this release

  • Grants
  • Trials
  • Comments and corrections
  • Genes
  • Drugs
  • Data

Sources 11

  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • HGNCCC0
  • iCiteCC BY 4.0
  • NCBI GenePublic domain (US government)
  • NIH RePORTER's grant and paper linksPublic domain
  • Open TargetsCC0 1.0
  • PMC's ID filePublic domain (US government)
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • HGNCCC0: https://www.genenames.org/about/license/
  • iCiteCC BY 4.0
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH RePORTER's grant and paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PMC's ID fileNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this paper from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/papers/v1/64327

GET https://conductscience.org/api/papers/v1/64327/authors

API referenceFor AI assistants