Paper6447166
Heterogeneity of b lymphocyte differentiation in severe combined immunodeficiency disease.
Pahwa SG and 2 others. J Clin Invest, 1980. Cited by 26 papers, by iCite.
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ConductScience Library. Heterogeneity of b lymphocyte differentiation in severe combined immunodeficiency disease. Papers, record 6447166. Release papers-2026-11-12-0.1.0, 12 Nov 2026. https://conductscience.org/library/papers/6447166
Paper
PubMed's record of the paper, with iCite's citation figures. No abstract is shown.
- Title
- Heterogeneity of b lymphocyte differentiation in severe combined immunodeficiency disease.
- PubMed
Topics12
NLM's MeSH indexing of the paper, its major topics first.
| MeSH term | Major |
|---|---|
| B-Lymphocytes | Major topic |
| Immunologic Deficiency Syndromes | Major topic |
| Adenosine Deaminase | |
| Bone Marrow Cells | |
| Cell Differentiation | |
| Child, Preschool | |
| Hemolytic Plaque Technique | |
| Humans | |
| Infant | |
| Monocytes | |
| T-Lymphocytes | |
| T-Lymphocytes, Regulatory |
Source PubMed
References31
The papers the reference list in PubMed's record names, those in our copy of PubMed, in the list's order.
| Order | PMID | Title | Journal | Year | In Papers | Source |
|---|---|---|---|---|---|---|
| 1 | 5,783,244 | Separation of cells by velocity sedimentation. | J Cell Physiol | 1969 | https://conductscience.org/library/papers/5783244 | PubMed |
| 2 | 4,117,384 | Adenosine-deaminase deficiency in two patients with severely impaired cellular immunity. | Lancet | 1972 | https://conductscience.org/library/papers/4117384 | PubMed |
| 3 | 4,357,270 | Enhanced binding of neuraminidase-treated sheep erythrocytes to human T lymphocytes. | Blood | 1973 | https://conductscience.org/library/papers/4357270 | PubMed |
| 4 | 4,587,502 | Successful treatment of an infant with severe combined immunodeficiency by transplantation of bone marrow cells from an uncle. | Clin Exp Immunol | 1973 | https://conductscience.org/library/papers/4587502 | PubMed |
| 5 | 4,549,205 | Human lymphocyte-sheep erythrocyte rosette formation: some characteristics of the interaction. | Clin Immunol Immunopathol | 1973 | https://conductscience.org/library/papers/4549205 | PubMed |
| 6 | 1,097,926 | Demonstration of an intrathymic defect in a case of severe combined immunodeficiency disease. | N Engl J Med | 1975 | https://conductscience.org/library/papers/1097926 | PubMed |
| 7 | 4,549,567 | Differentiation of human bone marrow cells into T lymphocytes by in vitro incubation with thymic extracts. | Clin Exp Immunol | 1974 | https://conductscience.org/library/papers/4549567 | PubMed |
| 8 | 52,774 | Restoration of in-vitro lymphocyte responses with exogenous adenosine deaminase in a patient with severe combined immunodeficiency. | Lancet | 1975 | https://conductscience.org/library/papers/52774 | PubMed |
| 9 | 3,737 | Correction of severe combined immunodeficiency by fetal liver cells. | N Engl J Med | 1976 | https://conductscience.org/library/papers/3737 | PubMed |
| 10 | 58,799 | Antigen-specific T-cell factor in cell cooperation and genetic control of the immune response. | Fed Proc | 1976 | https://conductscience.org/library/papers/58799 | PubMed |
| 11 | 1,084,354 | Heterogeneity of lymphocyte subpopulations in severe combined immunodeficiency. Evidence against a stem cell defect. | J Clin Invest | 1976 | https://conductscience.org/library/papers/1084354 | PubMed |
| 12 | 780,023 | Is the B-cell abnormality secondary to T-cell abnormality in severe combined immunodeficiency?1. | Clin Immunol Immunopathol | 1976 | https://conductscience.org/library/papers/780023 | PubMed |
| 13 | 1,085,339 | Properties of the antigen-specific suppressive T-cell factor in the regulation of antibody response of the mouse. IV. Special subregion assignment of the gene(s) that codes for the suppressive T-cell factor in the H-2 histocompatibility complex. | J Exp Med | 1976 | https://conductscience.org/library/papers/1085339 | PubMed |
| 14 | 1,066,699 | Purine metabolism in adenosine deaminase deficiency. | Proc Natl Acad Sci U S A | 1976 | https://conductscience.org/library/papers/1066699 | PubMed |
| 15 | 786,520 | Heterogeneity of stem cells in severe combined immunodeficiency. | Clin Exp Immunol | 1976 | https://conductscience.org/library/papers/786520 | PubMed |
| 16 | 980,079 | Enzyme replacement therapy for adenosine deaminase deficiency and severe combined immunodeficiency. | N Engl J Med | 1976 | https://conductscience.org/library/papers/980079 | PubMed |
| 17 | 790,392 | Polyclonal activation of bone-marrow-derived lymphocytes from human peripheral blood measured by a direct plaque-forming cell assay. | Proc Natl Acad Sci U S A | 1976 | https://conductscience.org/library/papers/790392 | PubMed |
| 18 | 1,087,209 | Severe combined immunodeficiency with B lymphocytes: in vitro correction of defective immunoglobulin production by addition of normal T lymphocytes. | Clin Exp Immunol | 1976 | https://conductscience.org/library/papers/1087209 | PubMed |
| 19 | 63,746 | Reconstitution of B and T lymphocyte function in severe combined immunodeficiency disease after transplantation with thymic epithelium. | Lancet | 1976 | https://conductscience.org/library/papers/63746 | PubMed |
| 20 | 300,089 | Enhancement by irradiated T cells of human plasma cell production: dissection of helper and suppressor functions in vitro. | J Immunol | 1977 | https://conductscience.org/library/papers/300089 | PubMed |
Cited by8
The papers in our copy of PubMed whose reference list names this one, newest first. iCite, which reads more sources, counts 26 citations.
| PMID | Title | Journal | Year | In Papers | Source |
|---|---|---|---|---|---|
| 7,141,511 | Lymphocyte subpopulations in primary immunodeficiency disorders. | Indian J Pediatr | 1982 | https://conductscience.org/library/papers/7141511 | PubMed |
| 3,899,661 | Severe combined immunodeficiency: treatment by bone marrow transplantation in 15 infants using HLA-haploidentical donors. | Eur J Pediatr | 1985 | https://conductscience.org/library/papers/3899661 | PubMed |
| 3,473,485 | Prematurity, hypogammaglobulinemia, and neuropathology with human immunodeficiency virus (HIV) infection. | Proc Natl Acad Sci U S A | 1987 | https://conductscience.org/library/papers/3473485 | PubMed |
| 3,081,578 | Defective expression of T cell-associated glycoprotein in severe combined immunodeficiency. | J Clin Invest | 1986 | https://conductscience.org/library/papers/3081578 | PubMed |
| 2,896,355 | Nonrandom X chromosome inactivation in B cells from carriers of X chromosome-linked severe combined immunodeficiency. | Proc Natl Acad Sci U S A | 1988 | https://conductscience.org/library/papers/2896355 | PubMed |
| 2,833,436 | Abnormalities in DNA rearrangements of immunoglobulin gene loci in precursor B cells derived from X-linked agammaglobulinemia patient and a severe combined immunodeficiency patient. | Immunogenetics | 1988 | https://conductscience.org/library/papers/2833436 | PubMed |
| 2,787,027 | Recombinant interleukin 2 therapy in severe combined immunodeficiency disease. | Proc Natl Acad Sci U S A | 1989 | https://conductscience.org/library/papers/2787027 | PubMed |
| 1,863,997 | Genetics of human X-linked immunodeficiency diseases. | Clin Exp Immunol | 1991 | https://conductscience.org/library/papers/1863997 | PubMed |
Genes1
The genes the Gene search release ties to the paper: Swiss-Prot's references first, then PubTator's text mining.
| Gene | NCBI Gene ID | Linked by | In Genes |
|---|---|---|---|
| ADA | 100 | PubTator's text mining | https://conductscience.org/library/genes/100 |
Source NCBI Gene
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- 2026-11-12
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- 2026-11-11
- Pipelines
- 2026-09-18
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- ClinicalTrials.govNo license stated
- HGNCCC0
- iCiteCC BY 4.0
- NCBI GenePublic domain (US government)
- NIH RePORTER's grant and paper linksPublic domain
- Open TargetsCC0 1.0
- PMC's ID filePublic domain (US government)
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
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- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- HGNCCC0: https://www.genenames.org/about/license/
- iCiteCC BY 4.0
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH RePORTER's grant and paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PMC's ID fileNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
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