ConductScience.org, home
Papers
API referenceFor AI assistants

Paper790392

Polyclonal activation of bone-marrow-derived lymphocytes from human peripheral blood measured by a direct plaque-forming cell assay.

Fauci AS and 1 other. Proc Natl Acad Sci U S A, 1976. Cited by 126 papers, by iCite.

11 sourcespapers-2026-11-12-0.1.0

Download JSON
Cite this record

ConductScience Library. Polyclonal activation of bone-marrow-derived lymphocytes from human peripheral blood measured by a direct plaque-forming cell assay. Papers, record 790392. Release papers-2026-11-12-0.1.0, 12 Nov 2026. https://conductscience.org/library/papers/790392

Paper

PubMed's record of the paper, with iCite's citation figures. No abstract is shown.

Title
Polyclonal activation of bone-marrow-derived lymphocytes from human peripheral blood measured by a direct plaque-forming cell assay.
PubMed
Journal
Proc Natl Acad Sci U S A
PubMed
Year
1976
PubMed
Publication types
Journal Article
PubMed
Citations, by iCite
126
iCite
Relative citation ratio, by iCite
4.07
iCite
Revised in PubMed
2019-05-01
PubMed

Authors2

The authors in the order PubMed's record lists them, with the ORCID iDs it states.

OrderAuthorForenameKindORCID iD
1Fauci ASA S
2Pratt KRK R

Source PubMed

Topics11

NLM's MeSH indexing of the paper, its major topics first.

MeSH termMajor
Antibody FormationMajor topic
B-LymphocytesMajor topic
Blood
Culture Media
Escherichia coli
Hemolytic Plaque Technique
Humans
Lectins
Lipopolysaccharides
Polysaccharides, Bacterial
Time Factors

Source PubMed

References13

The papers the reference list in PubMed's record names, those in our copy of PubMed, in the list's order.

OrderPMIDTitleJournalYearIn PapersSource
113,957,684Plaque formation in agar by single antibody-producing cells.Science1963https://conductscience.org/library/papers/13957684PubMed
24,200,776
Interaction of human thymus-derived and non-thymus-derived lymphocytes in vitro. Induction of proliferation and antibody synthesis in B lymphocytes by a soluble factor released from antigen-stimulated T lymphocytes.
J Exp Med1973https://conductscience.org/library/papers/4200776PubMed
34,137,918Role of suppressor T cells in pathogenesis of common variable hypogammaglobulinaemia.Lancet1974https://conductscience.org/library/papers/4137918PubMed
44,106,608Agammaglobulinaemia with B lymphocytes. Specific defect of plasma-cell differentiation.Lancet1971https://conductscience.org/library/papers/4106608PubMed
54,615,402Plaque forming cells: methodology and theory.Transplant Rev1974https://conductscience.org/library/papers/4615402PubMed
64,602,663In vitro antibody formation by human tonsil lymphocytes.J Immunol1974https://conductscience.org/library/papers/4602663PubMed
76,034,749Immunization of dissociated spleen cell cultures from normal mice.J Exp Med1967https://conductscience.org/library/papers/6034749PubMed
84,582,752Production of antibody to sheep red blood cells by human tonsil cells in vitro.Nature1973https://conductscience.org/library/papers/4582752PubMed
9784,890Activation of human B lymphocytes. I. Direct plaque-forming cell assay for the measurement of polyclonal activation and antigenic stimulation of human B lymphocytes.J Exp Med1976https://conductscience.org/library/papers/784890PubMed
101,096,578Thymus-independent B-cell induction and paralysis.Adv Immunol1975https://conductscience.org/library/papers/1096578PubMed
111,096,382Functional analysis of murine and human B lymphocyte subsets.Transplant Rev1975https://conductscience.org/library/papers/1096382PubMed
12768,379Artifactual plaque formation in vitro and in vivo to passive transfer of specific antibody.J Immunol1976https://conductscience.org/library/papers/768379PubMed
1352,177Responsiveness of lymphoid precursors to polyclonal B-cell activators.Scand J Immunol1975https://conductscience.org/library/papers/52177PubMed

Cited by31

The papers in our copy of PubMed whose reference list names this one, newest first. iCite, which reads more sources, counts 126 citations.

PMIDTitleJournalYearIn PapersSource
7,471,516PPD-induced viral antibody production in human blood lymphocytes.Clin Exp Immunol1980https://conductscience.org/library/papers/7471516PubMed
7,037,827The maintenance of B-cell and T-cell function in frozen and stored human lymphocytes.J Clin Immunol1981https://conductscience.org/library/papers/7037827PubMed
7,016,220Impaired B-lymphocyte reactivity in patients with Hodgkin's disease and non-Hodgkin-lymphomas.Blut1981https://conductscience.org/library/papers/7016220PubMed
7,002,766Activation of human B lymphocytes. XII. Differential effects of in vitro cyclophosphamide on human lymphocyte subpopulations involved in B-cell activation.Immunology1980https://conductscience.org/library/papers/7002766PubMed
7,002,234Characteristics of immunoglobulin secretion in man evaluated by a reverse hemolytic plaque assay.Blut1980https://conductscience.org/library/papers/7002234PubMed
6,987,166Effect of rifampin on the immune response in mice.Infect Immun1980https://conductscience.org/library/papers/6987166PubMed
6,986,413In vitro idiotypic suppression of chronic lymphocytic leukemia lymphocytes secreting monoclonal immunoglobulin M anti-sheep erythrocyte antibody.J Clin Invest1980https://conductscience.org/library/papers/6986413PubMed
6,978,212Human anti-tetanus antibody response in vitro: autologous and allogeneic T cells provide help by different routes.Clin Exp Immunol1981https://conductscience.org/library/papers/6978212PubMed
6,977,551The role of mitogens and antigens in the generation of antibody-producing human B lymphocytes.J Clin Immunol1981https://conductscience.org/library/papers/6977551PubMed
6,975,240Polyclonal B-cell activation induced by extracts of Gram-negative bacteria isolated from periodontally diseased sites.Infect Immun1981https://conductscience.org/library/papers/6975240PubMed
6,974,218
Polyclonal activation of human B lymphocytes by Fc fragments. I. Characterization of the cellular requirements for Fc fragment-mediated polyclonal antibody secretion by human peripheral blood B lymphocytes.
J Exp Med1981https://conductscience.org/library/papers/6974218PubMed
6,972,434Polyclonal activation of human peripheral blood B lymphocytes by formaldehyde-fixed Salmonella paratyphi B. I. Immunoglobulin production without DNA synthesis.J Exp Med1981https://conductscience.org/library/papers/6972434PubMed
6,815,221Binding of sheep erythrocytes in chronic lymphocytic leukemias of B-cell origin.J Clin Immunol1982https://conductscience.org/library/papers/6815221PubMed
6,603,301Human B cell growth factors overcome T cell-mediated inhibition of specific antibody production: a possible mechanism for the exacerbation of autoimmune disease.Clin Exp Immunol1983https://conductscience.org/library/papers/6603301PubMed
6,602,145Immunologic studies of three family members with the immunodeficiency with hyper-IgM syndrome.J Clin Immunol1983https://conductscience.org/library/papers/6602145PubMed
6,454,698Fractionation and characterization of the immunosuppressive substance in crude extracellular products released by Streptococcus intermedius.J Clin Invest1981https://conductscience.org/library/papers/6454698PubMed
6,448,821Effect of fusidic acid on the immune response in mice.Infect Immun1980https://conductscience.org/library/papers/6448821PubMed
6,447,166Heterogeneity of b lymphocyte differentiation in severe combined immunodeficiency disease.J Clin Invest1980https://conductscience.org/library/papers/6447166PubMed
6,444,308Immunoregulation in Sjögren's syndrome: influence of serum factors on T-cell subpopulations.J Clin Invest1980https://conductscience.org/library/papers/6444308PubMed
6,234,112Immune responsiveness following intratracheal inoculation with Histoplasma capsulatum yeast cells.Clin Exp Immunol1984https://conductscience.org/library/papers/6234112PubMed

See all 31 cited by

Data dates

The date of each source this release read.

PubMed
2026-11-06
PubMed
iCite
2026-11-05
iCite
PMC's ID file
2026-11-05
PMC's ID file
NIH RePORTER's grant and paper links
2026-11-01
NIH RePORTER's grant and paper links
Trials
2026-11-12
Gene search
2026-11-11
Pipelines
2026-09-18

None in this release

  • Grants
  • Trials
  • Comments and corrections
  • Genes
  • Drugs
  • Data

Sources 11

  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • HGNCCC0
  • iCiteCC BY 4.0
  • NCBI GenePublic domain (US government)
  • NIH RePORTER's grant and paper linksPublic domain
  • Open TargetsCC0 1.0
  • PMC's ID filePublic domain (US government)
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • HGNCCC0: https://www.genenames.org/about/license/
  • iCiteCC BY 4.0
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH RePORTER's grant and paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PMC's ID fileNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this paper from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/papers/v1/790392

GET https://conductscience.org/api/papers/v1/790392/cited_by?page=2

API referenceFor AI assistants