Paper · 75008

Purification, biochemical characterization and serological analysis of cellular deoxyribonucleic acid polymerases and a reverse transcriptase from spleen of a patient with myelofibrotic syndrome.

Chandra P and 1 other. Biochem J, 1977. Cited by 48 papers, by iCite.

11 sourcespapers-2026-11-12-0.1.0

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ConductScience Library. Purification, biochemical characterization and serological analysis of cellular deoxyribonucleic acid polymerases and a reverse transcriptase from spleen of a patient with myelofibrotic syndrome. Papers, record 75008. Release papers-2026-11-12-0.1.0, 12 Nov 2026. https://conductscience.org/library/papers/75008

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Paper

PubMed's record of the paper, with iCite's citation figures. No abstract is shown.

Title: Purification, biochemical characterization and serological analysis of cellular deoxyribonucleic acid polymerases and a reverse transcriptase from spleen of a patient with myelofibrotic syndrome.; PubMed
Journal: Biochem J; PubMed
Year: 1977; PubMed
Publication types: Journal Article; PubMed
PubMed: https://pubmed.ncbi.nlm.nih.gov/75008/; PubMed
DOI: https://doi.org/10.1042/bj1670513f; PubMed
PMC: https://pmc.ncbi.nlm.nih.gov/articles/PMC1183697/; PubMed
The journal: https://conductscience.org/library/journal-index/2984726R; PubMed
Citations, by iCite: 48; iCite
Relative citation ratio, by iCite: 1.27; iCite
Revised in PubMed: 2019-05-01; PubMed

Authors2

The authors in the order PubMed's record lists them, with the ORCID iDs it states.

Order	Author	Forename	Kind	ORCID iD
1	Chandra P	P
2	Steel LK	L K

Source PubMed

Topics11

NLM's MeSH indexing of the paper, its major topics first.

MeSH term	Major
DNA-Directed DNA Polymerase	Major topic
Primary Myelofibrosis	Major topic
RNA-Directed DNA Polymerase	Major topic
Spleen	Major topic
Child, Preschool
Chromatography
Female
Humans
Molecular Weight
Syndrome
Templates, Genetic

Source PubMed

Grants0

Each grant PubMed's record writes, matched to the NIH project NIH's grant and paper links name for this paper, and each of those links the record does not write.

None in this release.

Trials0

The trials whose ClinicalTrials.gov record lists the paper, and the trial numbers the paper's PubMed record names.

None in this release.

Comments and corrections0

PubMed's comments and corrections, NLM's own indexing: retractions first, then expressions of concern, errata and updates, and comments last.

None in this release.

References35

The papers the reference list in PubMed's record names, those in our copy of PubMed, in the list's order.

Order	PMID	Title	Journal	Year	In Papers	Source
3	13,767,412	A method for determining the sedimentation behavior of enzymes: application to protein mixtures.	J Biol Chem	1961	https://conductscience.org/library/papers/13767412	PubMed
4	13,802,334	Calf thymus polymerase.	J Biol Chem	1960	https://conductscience.org/library/papers/13802334	PubMed
5	14,038,381	A clinical and pathological study of seventy cases of myelofibrosis.	Ann Intern Med	1962	https://conductscience.org/library/papers/14038381	PubMed
6	14,240,533	DISC ELECTROPHORESIS. I. BACKGROUND AND THEORY.	Ann N Y Acad Sci	1964	https://conductscience.org/library/papers/14240533	PubMed
7	14,240,539	DISC ELECTROPHORESIS. II. METHOD AND APPLICATION TO HUMAN SERUM PROTEINS.	Ann N Y Acad Sci	1964	https://conductscience.org/library/papers/14240539	PubMed
9	170,528	Isolation of infectious C-type oncornavirus from human leukaemic bone marrow cells.	Nature	1975	https://conductscience.org/library/papers/170528	PubMed
10	4,117,352	Reversible inactivation of the deoxyribonucleic acid polymerase of Rauscher leukemia virus.	J Virol	1972	https://conductscience.org/library/papers/4117352	PubMed
11	4,118,867	Ribonuclease H: a ubiquitous activity in virions of ribonucleic acid tumor viruses.	J Virol	1972	https://conductscience.org/library/papers/4118867	PubMed
12	4,126,783	Immunological relationship of DNA polymerase from human acute leukaemia cells and primate and mouse leukaemia virus reverse transcriptase.	Nature	1973	https://conductscience.org/library/papers/4126783	PubMed
13	4,127,027	Purification, characterization, and comparison of the DNA polymerases from two primate RNA tumor viruses.	J Virol	1973	https://conductscience.org/library/papers/4127027	PubMed

1 to 10 of 35

See all 35 references

Cited by8

The papers in our copy of PubMed whose reference list names this one, newest first. iCite, which reads more sources, counts 48 citations.

PMID	Title	Journal	Year	In Papers	Source
6,319,800	RNA-tumorviruses, oncogenes, and their possible role in human carcinogenesis.	Klin Wochenschr	1983	https://conductscience.org/library/papers/6319800	PubMed
6,246,270	Relationship of retroviruses isolated from human leukemia tissues to the woolly monkey-gibbon ape leukemia viruses.	J Virol	1980	https://conductscience.org/library/papers/6246270	PubMed
6,196,826	Immunological characterization of reverse transcriptase from human tumor tissues.	Surv Immunol Res	1983	https://conductscience.org/library/papers/6196826	PubMed
6,173,035	Evidence for two forms of reverse transcriptase in human placenta of a patient with breast cancer. Purification and biochemical characterization of the enzymes.	Biochem J	1981	https://conductscience.org/library/papers/6173035	PubMed
6,159,025	Human leukemia viruses? RNA tumor viruses, human malignancies, and concepts of viral carcinogenesis.	Blut	1980	https://conductscience.org/library/papers/6159025	PubMed
1,714,378	Authentic reverse transcriptase is coded by jockey, a mobile Drosophila element related to mammalian LINEs.	EMBO J	1991	https://conductscience.org/library/papers/1714378	PubMed
1,698,616	Reverse transcriptase activity from human embryonal carcinoma cells NTera2D1.	EMBO J	1990	https://conductscience.org/library/papers/1698616	PubMed
545,833	The association of viruses with urveal melanoma.	Trans Am Ophthalmol Soc	1979	https://conductscience.org/library/papers/545833	PubMed

Genes3

The genes the Gene search release ties to the paper: Swiss-Prot's references first, then PubTator's text mining.

Gene	NCBI Gene ID	Linked by	In Genes	Source
POLA1	5,422	PubTator's text mining	https://conductscience.org/library/genes/5422	NCBI Gene
POLB	5,423	PubTator's text mining	https://conductscience.org/library/genes/5423	NCBI Gene
POLG	5,428	PubTator's text mining	https://conductscience.org/library/genes/5428	NCBI Gene

Drugs0

The drugs whose trials, in the Pipelines release, list the paper.

None in this release.

Data0

The data bank entries PubMed's record names. Trial numbers are under Trials.

None in this release.

Data dates

The date of each source this release read.

PubMed: 2026-11-06; PubMed
iCite: 2026-11-05; iCite
PMC's ID file: 2026-11-05; PMC's ID file
NIH RePORTER's grant and paper links: 2026-11-01; NIH RePORTER's grant and paper links
Trials: 2026-11-12
Gene search: 2026-11-11
Pipelines: 2026-09-18

Sources 11

ChEMBL, through Open TargetsCC BY-SA 3.0
ClinicalTrials.govNo license stated
HGNCCC0
iCiteCC BY 4.0
NCBI GenePublic domain (US government)
NIH RePORTER's grant and paper linksPublic domain
Open TargetsCC0 1.0
PMC's ID filePublic domain (US government)
PubMedNLM's terms
PubTator 3Public domain
UniProtCC BY 4.0

Each source's terms

ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
ClinicalTrials.govnone stated
HGNCCC0: https://www.genenames.org/about/license/
iCiteCC BY 4.0
NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
NIH RePORTER's grant and paper linksPublic domain (NIH RePORTER)
Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
PMC's ID fileNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
PubMedNLM's terms
PubTator 3Public domain
UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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