Paper · 77304

A new lymphocyte-activating determinant locus expressed on T cells, and mapping in I-C subregion.

Okuda K and 1 other. J Exp Med, 1978. Cited by 26 papers, by iCite.

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ConductScience Library. A new lymphocyte-activating determinant locus expressed on T cells, and mapping in I-C subregion. Papers, record 77304. Release papers-2026-11-12-0.1.0, 12 Nov 2026. https://conductscience.org/library/papers/77304

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Paper

PubMed's record of the paper, with iCite's citation figures. No abstract is shown.

Title: A new lymphocyte-activating determinant locus expressed on T cells, and mapping in I-C subregion.; PubMed
Journal: J Exp Med; PubMed
Year: 1978; PubMed
Publication types: Journal Article, Research Support, U.S. Gov't, P.H.S.; PubMed
PubMed: https://pubmed.ncbi.nlm.nih.gov/77304/; PubMed
DOI: https://doi.org/10.1084/jem.147.4.1028; PubMed
PMC: https://pmc.ncbi.nlm.nih.gov/articles/PMC2184250/; PubMed
The journal: https://conductscience.org/library/journal-index/2985109R; PubMed
Citations, by iCite: 26; iCite
Relative citation ratio, by iCite: 0.56; iCite
Revised in PubMed: 2019-05-08; PubMed

Authors2

The authors in the order PubMed's record lists them, with the ORCID iDs it states.

Order	Author	Forename	Kind	ORCID iD
1	Okuda K	K
2	David CS	C S

Source PubMed

Topics15

NLM's MeSH indexing of the paper, its major topics first.

MeSH term	Major
Genes, MHC Class II	Major topic
H-2 Antigens	Major topic
T-Lymphocytes	Major topic
Animals
Antigen-Antibody Reactions
B-Lymphocytes
Chromosome Mapping
Epitopes
Immunity, Cellular
Isoantibodies
Isoantigens
Lymph Nodes
Lymphocyte Culture Test, Mixed
Mice
Spleen

Source PubMed

Grants0

Each grant PubMed's record writes, matched to the NIH project NIH's grant and paper links name for this paper, and each of those links the record does not write.

None in this release.

Trials0

The trials whose ClinicalTrials.gov record lists the paper, and the trial numbers the paper's PubMed record names.

None in this release.

Comments and corrections0

PubMed's comments and corrections, NLM's own indexing: retractions first, then expressions of concern, errata and updates, and comments last.

None in this release.

References18

The papers the reference list in PubMed's record names, those in our copy of PubMed, in the list's order.

Order	PMID	Title	Journal	Year	In Papers	Source
1	1,059,157	Complementation of H-2-linked Ir genes in the mouse.	Proc Natl Acad Sci U S A	1975	https://conductscience.org/library/papers/1059157	PubMed
2	1,086,882	Regulatory mechanisms in cell-mediated immune responses. IV. Expression of a receptor for mixed lymphocyte reaction suppressor factor on activated T lymphocytes.	J Exp Med	1976	https://conductscience.org/library/papers/1086882	PubMed
3	1,090,452	Development of B lymphocytes-1,2.	Fed Proc	1975	https://conductscience.org/library/papers/1090452	PubMed
4	123,542	Characterization of immune response and mixed lymphocyte reactions in selected intra-H-2 recombinant strains.	J Immunol	1975	https://conductscience.org/library/papers/123542	PubMed
5	129,500	Regulatory mechanisms in cell-mediated immune responses. III. I-region control of suppressor cell interaction with responder cells in mixed lymphocyte reactions.	J Exp Med	1976	https://conductscience.org/library/papers/129500	PubMed
6	144,771	The role of gene products of the I-J subregion in mixed lymphocyte reactions.	J Exp Med	1977	https://conductscience.org/library/papers/144771	PubMed
7	302,172	Serological and functional evidence for further subdivision of the I regions of the H-2 gene complex.	Cold Spring Harb Symp Quant Biol	1977	https://conductscience.org/library/papers/302172	PubMed
8	4,266,664	A major role for the Ir-1 region of the mouse H-2 complex in the mixed leukocyte reaction.	Transplant Proc	1973	https://conductscience.org/library/papers/4266664	PubMed
9	4,502,414	Comparison of mitomycin C and X-irradiation as blocking agents in one-way mixed leucocyte cultures.	Nat New Biol	1972	https://conductscience.org/library/papers/4502414	PubMed
10	4,517,664	New lymphocyte antigen system (Lna) controlled by the Ir region of the mouse H-2 complex.	Proc Natl Acad Sci U S A	1973	https://conductscience.org/library/papers/4517664	PubMed

1 to 10 of 18

See all 18 references

Cited by6

The papers in our copy of PubMed whose reference list names this one, newest first. iCite, which reads more sources, counts 26 citations.

PMID	Title	Journal	Year	In Papers	Source
6,949,860	Production of a cytotoxic Ia.6-specific antibody.	Immunogenetics	1981	https://conductscience.org/library/papers/6949860	PubMed
6,407,984	H-2 haplotypes, genes and antigens: second listing. II. The H-2 complex.	Immunogenetics	1983	https://conductscience.org/library/papers/6407984	PubMed
6,161,371	Murine T cell Ia antigens: specificity Iat.46 maps in I-J to I-E chromosomal segment of H-2 complex.	Proc Natl Acad Sci U S A	1980	https://conductscience.org/library/papers/6161371	PubMed
448,292	Evidence for two homologous, but nonidentical, Ia molecules determined by the I-EC subregion.	J Exp Med	1979	https://conductscience.org/library/papers/448292	PubMed
91,654	Regulatory mechanisms in cell-mediated immune responses. VIII. Differential expression of I-region determinants by suppressor cells and their targets in suppression of mixed leukocyte reactions.	J Exp Med	1979	https://conductscience.org/library/papers/91654	PubMed
84,040	Regulatory mechanisms in cell-mediated immune responses. VII. Presence of I-C subregion determinants on mixed leukocyte reaction suppressor factor.	J Exp Med	1979	https://conductscience.org/library/papers/84040	PubMed

Genes0

The genes the Gene search release ties to the paper: Swiss-Prot's references first, then PubTator's text mining.

None in this release.

Drugs0

The drugs whose trials, in the Pipelines release, list the paper.

None in this release.

Data0

The data bank entries PubMed's record names. Trial numbers are under Trials.

None in this release.

Data dates

The date of each source this release read.

PubMed: 2026-11-06; PubMed
iCite: 2026-11-05; iCite
PMC's ID file: 2026-11-05; PMC's ID file
NIH RePORTER's grant and paper links: 2026-11-01; NIH RePORTER's grant and paper links
Trials: 2026-11-12
Gene search: 2026-11-11
Pipelines: 2026-09-18

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ClinicalTrials.govNo license stated
HGNCCC0
iCiteCC BY 4.0
NCBI GenePublic domain (US government)
NIH RePORTER's grant and paper linksPublic domain
Open TargetsCC0 1.0
PMC's ID filePublic domain (US government)
PubMedNLM's terms
PubTator 3Public domain
UniProtCC BY 4.0

Each source's terms

ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
ClinicalTrials.govnone stated
HGNCCC0: https://www.genenames.org/about/license/
iCiteCC BY 4.0
NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
NIH RePORTER's grant and paper linksPublic domain (NIH RePORTER)
Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
PMC's ID fileNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
PubMedNLM's terms
PubTator 3Public domain
UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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