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Paper91654

Regulatory mechanisms in cell-mediated immune responses. VIII. Differential expression of I-region determinants by suppressor cells and their targets in suppression of mixed leukocyte reactions.

Rich SS and 1 other. J Exp Med, 1979. Cited by 20 papers, by iCite.

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ConductScience Library. Regulatory mechanisms in cell-mediated immune responses. VIII. Differential expression of I-region determinants by suppressor cells and their targets in suppression of mixed leukocyte reactions. Papers, record 91654. Release papers-2026-11-12-0.1.0, 12 Nov 2026. https://conductscience.org/library/papers/91654

Paper

PubMed's record of the paper, with iCite's citation figures. No abstract is shown.

Title
Regulatory mechanisms in cell-mediated immune responses. VIII. Differential expression of I-region determinants by suppressor cells and their targets in suppression of mixed leukocyte reactions.
PubMed
Journal
J Exp Med
PubMed
Year
1979
PubMed
Publication types
Journal Article, Research Support, U.S. Gov't, P.H.S.
PubMed
Citations, by iCite
20
iCite
Relative citation ratio, by iCite
0.47
iCite
Revised in PubMed
2021-12-03
PubMed

Authors2

The authors in the order PubMed's record lists them, with the ORCID iDs it states.

OrderAuthorForenameKindORCID iD
1Rich SSS S
2David CSC S

Source PubMed

Topics14

NLM's MeSH indexing of the paper, its major topics first.

MeSH termMajor
EpitopesMajor topic
Immunosuppression TherapyMajor topic
IsoantigensMajor topic
T-LymphocytesMajor topic
T-Lymphocytes, RegulatoryMajor topic
Animals
Lymphocyte Culture Test, Mixed
Male
Mice
Mice, Inbred A
Mice, Inbred BALB C
Mice, Inbred C57BL
Mice, Inbred CBA
Phenotype

Source PubMed

References30

The papers the reference list in PubMed's record names, those in our copy of PubMed, in the list's order.

OrderPMIDTitleJournalYearIn PapersSource
11,081,578Fc-receptors, Ia-antigens, and immunoglobulin on normal and activated mouse T lymphocytes.J Exp Med1975https://conductscience.org/library/papers/1081578PubMed
21,083,955Virus-specific T-cell-mediated cytotoxicity across the H-2 barrier to virus-altered alloantigen.Nature1976https://conductscience.org/library/papers/1083955PubMed
31,085,337Selective expression of H-2 (i-region) loci controlling determinants on helper and suppressor T lymphocytes.J Exp Med1976https://conductscience.org/library/papers/1085337PubMed
41,085,338A new I subregion (I-J) marked by a locus (Ia-4) controlling surface determinants on suppressor T lymphocytes.J Exp Med1976https://conductscience.org/library/papers/1085338PubMed
51,085,339
Properties of the antigen-specific suppressive T-cell factor in the regulation of antibody response of the mouse. IV. Special subregion assignment of the gene(s) that codes for the suppressive T-cell factor in the H-2 histocompatibility complex.
J Exp Med1976https://conductscience.org/library/papers/1085339PubMed
61,085,419Helper T cells recognise antigen and macrophage surface components simultaneously.Nature1976https://conductscience.org/library/papers/1085419PubMed
71,086,433Two-gene control of T-helper cell induction.Nature1976https://conductscience.org/library/papers/1086433PubMed
81,086,882Regulatory mechanisms in cell-mediated immune responses. IV. Expression of a receptor for mixed lymphocyte reaction suppressor factor on activated T lymphocytes.J Exp Med1976https://conductscience.org/library/papers/1086882PubMed
91,100,764Antigen-specific T-cell factor in cell cooperation. Mapping within the I region of the H-2 complex and ability to cooperate across allogeneic barriers.J Exp Med1975https://conductscience.org/library/papers/1100764PubMed
10129,500Regulatory mechanisms in cell-mediated immune responses. III. I-region control of suppressor cell interaction with responder cells in mixed lymphocyte reactions.J Exp Med1976https://conductscience.org/library/papers/129500PubMed
11303,682Enrichment of specific suppressor T cells and characterization of their surface markers.J Exp Med1977https://conductscience.org/library/papers/303682PubMed
12307,988Cellular interaction between cytotoxic and suppressor T cells against syngeneic tumors in the mouse.Cell Immunol1978https://conductscience.org/library/papers/307988PubMed
13308,984
Adaptive differentiation of murine lymphocytes. I. Both T and B lymphocytes differentiating in F1 transplanted to parental chimeras manifest preferential cooperative activity for partner lymphocytes derived from the same parental type corresponding to the chimeric host.
J Exp Med1978https://conductscience.org/library/papers/308984PubMed
14312,873Genetic control of immune response to sperm whale myoglobin in mice. II. T lymphocyte proliferative response to the synthetic antigenic sites.J Immunol1979https://conductscience.org/library/papers/312873PubMed
154,540,455The separation of different cell classes from lymphoid organs. IX. A simple and rapid method for removal of damaged cells from lymphoid cell suspensions.J Immunol Methods1973https://conductscience.org/library/papers/4540455PubMed
164,587,740A rapid method for the isolation of functional thymus-derived murine lymphocytes.Eur J Immunol1973https://conductscience.org/library/papers/4587740PubMed
1747,219The H-2 major histocompatibility complex and the I immune response region: genetic variation, function, and organization.Adv Immunol1975https://conductscience.org/library/papers/47219PubMed
1853,264Regulatory mechanisms in cell-mediated immune responses. II. A genetically restricted suppressor of mixed lymphocyte reactions released by alloantigen-activated spleen cells.J Exp Med1975https://conductscience.org/library/papers/53264PubMed
1953,267Expression of individual Ia specificities on T and B cells. I. Studies with mitogen-induced blast cells.J Exp Med1976https://conductscience.org/library/papers/53267PubMed
2055,461Specific binding of alloantigens to T cells activated in the mixed lymphocyte reaction.J Exp Med1976https://conductscience.org/library/papers/55461PubMed

See all 30 references

Cited by5

The papers in our copy of PubMed whose reference list names this one, newest first. iCite, which reads more sources, counts 20 citations.

PMIDTitleJournalYearIn PapersSource
6,460,694Requirement for the location of both appropriate and irrelevant H-2 antigens on the same stimulator cell for unspecific DNA-synthesis inhibition by the H-2-antigen-primed, specific suppressor T cells.Immunogenetics1982https://conductscience.org/library/papers/6460694PubMed
6,215,457Suppressor T cells activated in a primary in vitro response to non-major histocompatibility alloantigens.J Exp Med1982https://conductscience.org/library/papers/6215457PubMed
6,201,587Suppressor T cell growth and differentiation. Identification of a cofactor required for suppressor T cell function and distinct from interleukin 2.J Exp Med1984https://conductscience.org/library/papers/6201587PubMed
6,193,232Regulatory mechanisms in cell-mediated immune responses. Role of I-J and I-C determinants in the activation of H-2I and H-2K/D alloantigen-specific suppressor T cells.J Exp Med1983https://conductscience.org/library/papers/6193232PubMed
6,161,371Murine T cell Ia antigens: specificity Iat.46 maps in I-J to I-E chromosomal segment of H-2 complex.Proc Natl Acad Sci U S A1980https://conductscience.org/library/papers/6161371PubMed

Genes1

The genes the Gene search release ties to the paper: Swiss-Prot's references first, then PubTator's text mining.

GeneNCBI Gene IDLinked byIn Genes
THY17,070PubTator's text mininghttps://conductscience.org/library/genes/7070

Source NCBI Gene

Data dates

The date of each source this release read.

PubMed
2026-11-06
PubMed
iCite
2026-11-05
iCite
PMC's ID file
2026-11-05
PMC's ID file
NIH RePORTER's grant and paper links
2026-11-01
NIH RePORTER's grant and paper links
Trials
2026-11-12
Gene search
2026-11-11
Pipelines
2026-09-18

None in this release

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  • Comments and corrections
  • Drugs
  • Data

Sources 11

  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • HGNCCC0
  • iCiteCC BY 4.0
  • NCBI GenePublic domain (US government)
  • NIH RePORTER's grant and paper linksPublic domain
  • Open TargetsCC0 1.0
  • PMC's ID filePublic domain (US government)
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • HGNCCC0: https://www.genenames.org/about/license/
  • iCiteCC BY 4.0
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH RePORTER's grant and paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PMC's ID fileNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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