Paper53264
Regulatory mechanisms in cell-mediated immune responses. II. A genetically restricted suppressor of mixed lymphocyte reactions released by alloantigen-activated spleen cells.
Rich SS and 1 other. J Exp Med, 1975. Cited by 127 papers, by iCite.
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ConductScience Library. Regulatory mechanisms in cell-mediated immune responses. II. A genetically restricted suppressor of mixed lymphocyte reactions released by alloantigen-activated spleen cells. Papers, record 53264. Release papers-2026-11-12-0.1.0, 12 Nov 2026. https://conductscience.org/library/papers/53264
Paper
PubMed's record of the paper, with iCite's citation figures. No abstract is shown.
- Title
- Regulatory mechanisms in cell-mediated immune responses. II. A genetically restricted suppressor of mixed lymphocyte reactions released by alloantigen-activated spleen cells.
- PubMed
- Publication types
- Journal Article, Research Support, U.S. Gov't, Non-P.H.S., Research Support, U.S. Gov't, P.H.S.
- PubMed
Topics15
NLM's MeSH indexing of the paper, its major topics first.
| MeSH term | Major |
|---|---|
| Histocompatibility Antigens | Major topic |
| Immunity, Cellular | Major topic |
| Lymphocyte Activation | Major topic |
| Spleen | Major topic |
| Animals | |
| Complement System Proteins | |
| Epitopes | |
| Immune Sera | |
| Isoantigens | |
| Lymphocyte Culture Test, Mixed | |
| Male | |
| Mice | |
| Mice, Inbred AKR | |
| Mice, Inbred BALB C | |
| Mice, Inbred Strains |
Source PubMed
References16
The papers the reference list in PubMed's record names, those in our copy of PubMed, in the list's order.
| Order | PMID | Title | Journal | Year | In Papers | Source |
|---|---|---|---|---|---|---|
| 1 | 5,124,960 | Mediators produced by sensitized lymphocytes. | Fed Proc | 1971 | https://conductscience.org/library/papers/5124960 | PubMed |
| 2 | 1,079,217 | Cell interactions between histoincompatible T and B lymphocytes. VIII. In vivo cooperative responses between lymphocytes are controlled by genes in the K-end of the H-2 complex. | J Immunol | 1975 | https://conductscience.org/library/papers/1079217 | PubMed |
| 3 | 1,090,698 | Cell interactions between histoincompatible T and B lymphocytes. VII. Cooperative responses between lymphocytes are controlled by genes in the I region of the H-2 complex. | J Exp Med | 1975 | https://conductscience.org/library/papers/1090698 | PubMed |
| 4 | 1,091,708 | Regulation of the immune response: production of a soluble suppressor by immune spleen cells in vitro. | J Immunol | 1975 | https://conductscience.org/library/papers/1091708 | PubMed |
| 5 | 4,122,709 | Cell interactions between histoincompatible T and B lymphocytes. II. Failure of physiologic cooperative interactions between T and B lymphocytes from allogeneic donor strains in humoral response to hapten-protein conjugates. | J Exp Med | 1973 | https://conductscience.org/library/papers/4122709 | PubMed |
| 6 | 4,139,236 | Activation of T and B lymphocytes in vitro. III. Presence of Ia determinants on allogeneic effect factor. | J Exp Med | 1974 | https://conductscience.org/library/papers/4139236 | PubMed |
| 7 | 4,216,017 | An inhibitor of cell proliferation released by cultures of macrophages. | Proc Natl Acad Sci U S A | 1974 | https://conductscience.org/library/papers/4216017 | PubMed |
| 8 | 4,279,271 | Regulatory mechanisms in cell-mediated immune responses. I. Regulation of mixed lymphocyte reactions by alloantigen-activated thymus-derived lymphocytes. | J Exp Med | 1974 | https://conductscience.org/library/papers/4279271 | PubMed |
| 9 | 4,538,719 | H-2 dependence of co-operation between T and B cells in vivo. | J Immunol | 1972 | https://conductscience.org/library/papers/4538719 | PubMed |
| 10 | 4,542,806 | Function of macrophages in antigen recognition by guinea pig T lymphocytes. I. Requirement for histocompatible macrophages and lymphocytes. | J Exp Med | 1973 | https://conductscience.org/library/papers/4542806 | PubMed |
| 11 | 4,545,893 | Activation of T and B lymphocytes in vitro. II. Biological and biochemical properties of an allogeneic effect factor (AEF) active in triggering specific B lymphocytes. | J Exp Med | 1974 | https://conductscience.org/library/papers/4545893 | PubMed |
| 12 | 4,545,898 | Cell interactions between histoincompatible T and B lymphocytes. VI. Cooperative responses between lymphocytes derived from mouse donor strains differing at genes in the S and D regions of the H-2 complex. | J Exp Med | 1974 | https://conductscience.org/library/papers/4545898 | PubMed |
| 13 | 4,594,643 | T cell factor which can replace T cells in vivo. | Nature | 1974 | https://conductscience.org/library/papers/4594643 | PubMed |
| 14 | 4,601,807 | T-cell-mediated immunopathology in viral infections. | Transplant Rev | 1974 | https://conductscience.org/library/papers/4601807 | PubMed |
| 15 | 4,610,078 | Antigen-specific T-cell factor in cell cooperation: physical properties and mapping in the left-hand (K) half of H-2. | J Exp Med | 1974 | https://conductscience.org/library/papers/4610078 | PubMed |
| 16 | 47,219 | The H-2 major histocompatibility complex and the I immune response region: genetic variation, function, and organization. | Adv Immunol | 1975 | https://conductscience.org/library/papers/47219 | PubMed |
Cited by30
The papers in our copy of PubMed whose reference list names this one, newest first. iCite, which reads more sources, counts 127 citations.
| PMID | Title | Journal | Year | In Papers | Source |
|---|---|---|---|---|---|
| 6,792,727 | Helper and suppressor T cell factors. | Springer Semin Immunopathol | 1980 | https://conductscience.org/library/papers/6792727 | PubMed |
| 6,461,714 | Allosuppressor and allohelper T cells in acute and chronic graft-vs-host disease. I. Alloreactive suppressor cells rather than killer T cells appear to be the decisive effector cells in lethal graft-vs.-host disease. | J Exp Med | 1982 | https://conductscience.org/library/papers/6461714 | PubMed |
| 6,459,996 | Regulation of the human allogenic proliferative response in vitro. II. Production of soluble suppressor factors by suppressor T cells and evidence in favor of "acceptor" cells for suppression among unprimed lymphocytes. | Immunogenetics | 1981 | https://conductscience.org/library/papers/6459996 | PubMed |
| 6,459,995 | Regulation of the human allogeneic proliferative response in vitro. | Immunogenetics | 1981 | https://conductscience.org/library/papers/6459995 | PubMed |
| 6,457,791 | Regulatory T cells in pregnancy. III. Comparison of early acting and late acting suppressor T cells in MLR: evidence for involvement of differential T-cell subsets. | Immunology | 1981 | https://conductscience.org/library/papers/6457791 | PubMed |
| 6,455,224 | Amplification and suppression of human T cell proliferative responses by alloactivated T cells. | Clin Exp Immunol | 1981 | https://conductscience.org/library/papers/6455224 | PubMed |
| 6,454,757 | Haplotype-specific suppression of antibody responses in vitro. II. Suppressor factor produced by T cells and T cell hybridomas from mice treated as neonates with semiallogeneic spleen cells. | J Exp Med | 1981 | https://conductscience.org/library/papers/6454757 | PubMed |
| 6,454,756 | Haplotype-specific suppression of antibody responses in vitro. I. Generation of genetically restricted suppressor T cells by neonatal treatment with semiallogeneic spleen cells. | J Exp Med | 1981 | https://conductscience.org/library/papers/6454756 | PubMed |
| 6,454,741 | Hapten-specific T cell responses to 4-hydroxy-3-nitrophenyl acetyl. VIII. Suppressor cell pathways in cutaneous sensitivity responses. | J Exp Med | 1981 | https://conductscience.org/library/papers/6454741 | PubMed |
| 6,452,237 | Relationship between T cell subpopulations and the mitogen responsiveness and suppressor cell function of peripheral blood mononuclear cells in normal individuals. | Clin Exp Immunol | 1980 | https://conductscience.org/library/papers/6452237 | PubMed |
| 6,449,474 | Limiting dilution analysis of the suppressive effect mediated by alloantigen-primed cells. | Immunology | 1980 | https://conductscience.org/library/papers/6449474 | PubMed |
| 6,227,676 | Suppressive mechanisms in alloantigen-induced T cell responses. | J Exp Med | 1983 | https://conductscience.org/library/papers/6227676 | PubMed |
| 6,212,626 | Spleen cells from adult mice given total lymphoid irradiation or from newborn mice have similar regulatory effects in the mixed leukocyte reaction. I. Generation of antigen-specific suppressor cells in the mixed leukocyte reaction after the addition of spleen cells from adult mice given total lymphoid irradiation. | J Exp Med | 1982 | https://conductscience.org/library/papers/6212626 | PubMed |
| 6,193,232 | Regulatory mechanisms in cell-mediated immune responses. Role of I-J and I-C determinants in the activation of H-2I and H-2K/D alloantigen-specific suppressor T cells. | J Exp Med | 1983 | https://conductscience.org/library/papers/6193232 | PubMed |
| 6,165,994 | Positive selection of major histocompatibility complex-restricted suppressor T cells bearing the predominant idiotype in the immune response to lysozyme. | Proc Natl Acad Sci U S A | 1981 | https://conductscience.org/library/papers/6165994 | PubMed |
| 2,936,685 | Immunoadsorption of Cryptococcus-specific suppressor T-cell factors. | Infect Immun | 1986 | https://conductscience.org/library/papers/2936685 | PubMed |
| 1,086,882 | Regulatory mechanisms in cell-mediated immune responses. IV. Expression of a receptor for mixed lymphocyte reaction suppressor factor on activated T lymphocytes. | J Exp Med | 1976 | https://conductscience.org/library/papers/1086882 | PubMed |
| 411,877 | The role of H-2-linked genes in helper T-cell function. I. In vitro expression in B cells of immune response genes controlling helper T-cell activity. | J Exp Med | 1977 | https://conductscience.org/library/papers/411877 | PubMed |
| 149,140 | Impaired cell-mediated immunity in Hodgkin's disease mediated by suppressor lymphocytes and monocytes. | J Clin Invest | 1978 | https://conductscience.org/library/papers/149140 | PubMed |
| 148,486 | Suppression of the mixed lymphocyte reaction in man by a soluble T-cell factor. Specificity of the factor for both responder and stimulator. | J Exp Med | 1978 | https://conductscience.org/library/papers/148486 | PubMed |
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- 2026-11-11
- Pipelines
- 2026-09-18
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- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- HGNCCC0
- iCiteCC BY 4.0
- NCBI GenePublic domain (US government)
- NIH RePORTER's grant and paper linksPublic domain
- Open TargetsCC0 1.0
- PMC's ID filePublic domain (US government)
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
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- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- HGNCCC0: https://www.genenames.org/about/license/
- iCiteCC BY 4.0
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH RePORTER's grant and paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PMC's ID fileNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
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