Paper · 7806571
Targeted disruption of the Dictyostelium RMLC gene produces cells defective in cytokinesis and development.
Chen P and 3 others. J Cell Biol, 1994. Cited by 79 papers, by iCite.
11 sourcespapers-2026-11-12-0.1.0
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ConductScience Library. Targeted disruption of the Dictyostelium RMLC gene produces cells defective in cytokinesis and development. Papers, record 7806571. Release papers-2026-11-12-0.1.0, 12 Nov 2026. https://conductscience.org/library/papers/7806571
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Paper
PubMed's record of the paper, with iCite's citation figures. No abstract is shown.
- Title
- Targeted disruption of the Dictyostelium RMLC gene produces cells defective in cytokinesis and development.
- PubMed
Topics17
NLM's MeSH indexing of the paper, its major topics first.
| MeSH term | Major |
|---|---|
| Dictyostelium | Major topic |
| Genes, Protozoan | Major topic |
| Myosins | Major topic |
| Actins | |
| Animals | |
| Blotting, Western | |
| Calcium-Transporting ATPases | |
| Cell Aggregation | |
| Cell Division | |
| Cytoskeleton | |
| DNA, Protozoan | |
| DNA, Recombinant | |
| Fluorescent Antibody Technique | |
| Microscopy, Fluorescence | |
| Mutagenesis | |
| Phenotype | |
| Transformation, Genetic |
Source PubMed
Grants1
Each grant PubMed's record writes, matched to the NIH project NIH's grant and paper links name for this paper, and each of those links the record does not write.
| Grant, as the record writes it | Agency | Country | NIH project | Stated by |
|---|---|---|---|---|
| GM39264 | NIGMS NIH HHS | United States | R01GM039264 | PubMed and NIH |
Source NIH RePORTER
Trials0
The trials whose ClinicalTrials.gov record lists the paper, and the trial numbers the paper's PubMed record names.
None in this release.
Comments and corrections1
PubMed's comments and corrections, NLM's own indexing: retractions first, then expressions of concern, errata and updates, and comments last.
| Kind | PMID | Title | In Papers |
|---|---|---|---|
| Comment in | 7,806,558 | Regulation of Dictyostelium myosin II by phosphorylation: what is essential and what is important? | https://conductscience.org/library/papers/7806558 |
Source PubMed
References55
The papers the reference list in PubMed's record names, those in our copy of PubMed, in the list's order.
| Order | PMID | Title | Journal | Year | In Papers | Source |
|---|---|---|---|---|---|---|
| 1 | 1,730,409 | Analysis of G alpha 4, a G-protein subunit required for multicellular development in Dictyostelium. | Genes Dev | 1992 | https://conductscience.org/library/papers/1730409 | PubMed |
| 2 | 1,535,025 | The Dictyostelium essential light chain is required for myosin function. | Cell | 1992 | https://conductscience.org/library/papers/1535025 | PubMed |
| 3 | 1,400,421 | Mapping single cysteine mutants of light chain 2 in chicken skeletal myosin. | J Biol Chem | 1992 | https://conductscience.org/library/papers/1400421 | PubMed |
| 4 | 1,464,306 | Chimeric myosin regulatory light chains identify the subdomain responsible for regulatory function. | EMBO J | 1992 | https://conductscience.org/library/papers/1464306 | PubMed |
| 5 | 8,388,631 | Myosin light chain phosphorylation in vertebrate striated muscle: regulation and function. | Am J Physiol | 1993 | https://conductscience.org/library/papers/8388631 | PubMed |
| 6 | 8,316,857 | Three-dimensional structure of myosin subfragment-1: a molecular motor. | Science | 1993 | https://conductscience.org/library/papers/8316857 | PubMed |
| 7 | 8,413,589 | Skeletal muscle myosin light chains are essential for physiological speeds of shortening. | Nature | 1993 | https://conductscience.org/library/papers/8413589 | PubMed |
| 8 | 8,266,074 | A functional recombinant myosin II lacking a regulatory light chain-binding site. | Science | 1993 | https://conductscience.org/library/papers/8266074 | PubMed |
| 9 | 8,132,717 | Coupling of ATPase activity and motility in smooth muscle myosin is mediated by the regulatory light chain. | J Cell Biol | 1994 | https://conductscience.org/library/papers/8132717 | PubMed |
| 10 | 7,806,572 | Expression of a myosin regulatory light chain phosphorylation site mutant complements the cytokinesis and developmental defects of Dictyostelium RMLC null cells. | J Cell Biol | 1994 | https://conductscience.org/library/papers/7806572 | PubMed |
1 to 10 of 55
See all 55 referencesCited by39
The papers in our copy of PubMed whose reference list names this one, newest first. iCite, which reads more sources, counts 79 citations.
| PMID | Title | Journal | Year | In Papers | Source |
|---|---|---|---|---|---|
| 38,334,655 | Suggesting Dictyostelium as a Model for Disease-Related Protein Studies through Myosin II Polymerization Pathway. | Cells | 2024 | https://conductscience.org/library/papers/38334655 | PubMed |
| 37,405,768 | Evidence that tissue recoil in the early Drosophila embryo is a passive not active process. | Mol Biol Cell | 2023 | https://conductscience.org/library/papers/37405768 | PubMed |
| 32,125,482 | Strategies for enhancing gene expression in Escherichia coli. | Appl Microbiol Biotechnol | 2020 | https://conductscience.org/library/papers/32125482 | PubMed |
| 30,808,751 | Functional integrity of the contractile actin cortex is safeguarded by multiple Diaphanous-related formins. | Proc Natl Acad Sci U S A | 2019 | https://conductscience.org/library/papers/30808751 | PubMed |
| 29,552,544 | Acanthamoeba and Dictyostelium as Cellular Models for Legionella Infection. | Front Cell Infect Microbiol | 2018 | https://conductscience.org/library/papers/29552544 | PubMed |
| 28,855,377 | Centrosome defines the rear of cells during mesenchymal migration. | Mol Biol Cell | 2017 | https://conductscience.org/library/papers/28855377 | PubMed |
| 28,034,796 | Mechanics and regulation of cytokinesis in budding yeast. | Semin Cell Dev Biol | 2017 | https://conductscience.org/library/papers/28034796 | PubMed |
| 25,872,182 | Genetic control of morphogenesis in Dictyostelium. | Dev Biol | 2015 | https://conductscience.org/library/papers/25872182 | PubMed |
| 25,631,819 | Myosin‑II heavy chain and formin mediate the targeting of myosin essential light chain to the division site before and during cytokinesis. | Mol Biol Cell | 2015 | https://conductscience.org/library/papers/25631819 | PubMed |
| 25,328,163 | Cytoskeletal Mechanics Regulating Amoeboid Cell Locomotion. | Appl Mech Rev | 2014 | https://conductscience.org/library/papers/25328163 | PubMed |
1 to 10 of 39
See all 39 cited byGenes1
The genes the Gene search release ties to the paper: Swiss-Prot's references first, then PubTator's text mining.
| Gene | NCBI Gene ID | Linked by | In Genes |
|---|---|---|---|
| MYH14 | 79,784 | PubTator's text mining | https://conductscience.org/library/genes/79784 |
Source NCBI Gene
Drugs0
The drugs whose trials, in the Pipelines release, list the paper.
None in this release.
Data0
The data bank entries PubMed's record names. Trial numbers are under Trials.
None in this release.
Data dates
The date of each source this release read.
- Trials
- 2026-11-12
- Gene search
- 2026-11-11
- Pipelines
- 2026-09-18
Sources 11
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- HGNCCC0
- iCiteCC BY 4.0
- NCBI GenePublic domain (US government)
- NIH RePORTER's grant and paper linksPublic domain
- Open TargetsCC0 1.0
- PMC's ID filePublic domain (US government)
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- HGNCCC0: https://www.genenames.org/about/license/
- iCiteCC BY 4.0
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH RePORTER's grant and paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PMC's ID fileNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
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