Paper · 7969164

The Saccharomyces cerevisiae checkpoint gene BUB1 encodes a novel protein kinase.

Roberts BT and 2 others. Mol Cell Biol, 1994. Cited by 187 papers, by iCite.

11 sourcespapers-2026-11-12-0.1.0

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ConductScience Library. The Saccharomyces cerevisiae checkpoint gene BUB1 encodes a novel protein kinase. Papers, record 7969164. Release papers-2026-11-12-0.1.0, 12 Nov 2026. https://conductscience.org/library/papers/7969164

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Paper

PubMed's record of the paper, with iCite's citation figures. No abstract is shown.

Title: The Saccharomyces cerevisiae checkpoint gene BUB1 encodes a novel protein kinase.; PubMed
Journal: Mol Cell Biol; PubMed
Year: 1994; PubMed
Publication types: Comparative Study, Journal Article, Research Support, U.S. Gov't, P.H.S.; PubMed
PubMed: https://pubmed.ncbi.nlm.nih.gov/7969164/; PubMed
DOI: https://doi.org/10.1128/mcb.14.12.8282-8291.1994; PubMed
PMC: https://pmc.ncbi.nlm.nih.gov/articles/PMC359367/; PubMed
The journal: https://conductscience.org/library/journal-index/8109087; PubMed
Citations, by iCite: 187; iCite
Relative citation ratio, by iCite: 2.89; iCite
Revised in PubMed: 2022-02-24; PubMed

Authors3

The authors in the order PubMed's record lists them, with the ORCID iDs it states.

Order	Author	Forename
1	Roberts BT	B T
2	Farr KA	K A
3	Hoyt MA	M A

Source PubMed

Topics19

NLM's MeSH indexing of the paper, its major topics first.

MeSH term	Major
Cell Cycle	Major topic
Cell Cycle Proteins	Major topic
Fungal Proteins	Major topic
Genes, Fungal	Major topic
Protein Kinases	Major topic
Saccharomyces cerevisiae	Major topic
Saccharomyces cerevisiae Proteins	Major topic
Amino Acid Sequence
Base Sequence
Cloning, Molecular
Molecular Sequence Data
Mutagenesis, Insertional
Nuclear Proteins
Protein Binding
Protein Serine-Threonine Kinases
Restriction Mapping
Sequence Alignment
Sequence Homology, Amino Acid
Structure-Activity Relationship

Source PubMed

Grants1

Each grant PubMed's record writes, matched to the NIH project NIH's grant and paper links name for this paper, and each of those links the record does not write.

Grant, as the record writes it	Agency	Country	NIH project	Stated by
GM49363	NIGMS NIH HHS	United States	R01GM049363	PubMed and NIH

Source NIH RePORTER

Trials0

The trials whose ClinicalTrials.gov record lists the paper, and the trial numbers the paper's PubMed record names.

None in this release.

Comments and corrections0

PubMed's comments and corrections, NLM's own indexing: retractions first, then expressions of concern, errata and updates, and comments last.

None in this release.

References34

The papers the reference list in PubMed's record names, those in our copy of PubMed, in the list's order.

Order	PMID	Title	Journal	Year	In Papers	Source
1	5,432,063	Cleavage of structural proteins during the assembly of the head of bacteriophage T4.	Nature	1970	https://conductscience.org/library/papers/5432063	PubMed
2	8,344,252	CAK, the p34cdc2 activating kinase, contains a protein identical or closely related to p40MO15.	EMBO J	1993	https://conductscience.org/library/papers/8344252	PubMed
3	7,028,745	Affinity purification of antibodies from diazotized paper blots of heterogeneous protein samples.	J Biol Chem	1981	https://conductscience.org/library/papers/7028745	PubMed
4	6,310,324	One-step gene disruption in yeast.	Methods Enzymol	1983	https://conductscience.org/library/papers/6310324	PubMed
5	3,881,765	Rapid and efficient site-specific mutagenesis without phenotypic selection.	Proc Natl Acad Sci U S A	1985	https://conductscience.org/library/papers/3881765	PubMed
6	3,526,554	A yeast gene that is essential for release from glucose repression encodes a protein kinase.	Science	1986	https://conductscience.org/library/papers/3526554	PubMed
7	3,540,600	Genetically essential and nonessential alpha-tubulin genes specify functionally interchangeable proteins.	Mol Cell Biol	1986	https://conductscience.org/library/papers/3540600	PubMed
8	3,323,813	Rapid and efficient site-specific mutagenesis without phenotypic selection.	Methods Enzymol	1987	https://conductscience.org/library/papers/3323813	PubMed
9	3,162,770	Improved tools for biological sequence comparison.	Proc Natl Acad Sci U S A	1988	https://conductscience.org/library/papers/3162770	PubMed
10	3,291,120	The RAD9 gene controls the cell cycle response to DNA damage in Saccharomyces cerevisiae.	Science	1988	https://conductscience.org/library/papers/3291120	PubMed

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Cited by92

The papers in our copy of PubMed whose reference list names this one, newest first. iCite, which reads more sources, counts 187 citations.

PMID	Title	Journal	Year	In Papers	Source
42,888,198	BUB signaling in cancer and molecular insights into targeted therapies.	Commun Biol	2026	https://conductscience.org/library/papers/42888198	PubMed
38,776,906	A conserved site on Ndc80 complex facilitates dynamic recruitment of Mps1 to yeast kinetochores to promote accurate chromosome segregation.	Curr Biol	2024	https://conductscience.org/library/papers/38776906	PubMed
38,763,998	TIP60 acetylation of Bub1 regulates centromeric H2AT120 phosphorylation for faithful chromosome segregation.	Sci China Life Sci	2024	https://conductscience.org/library/papers/38763998	PubMed
38,578,284	Phospho-KNL-1 recognition by a TPR domain targets the BUB-1-BUB-3 complex to C. elegans kinetochores.	J Cell Biol	2024	https://conductscience.org/library/papers/38578284	PubMed
38,463,586	Expression of circular RNA has-circ-0009158 and identification of associated miRNA-mRNA network in hepatocellular carcinoma.	Am J Transl Res	2024	https://conductscience.org/library/papers/38463586	PubMed
37,460,679	Toxicology knowledge graph for structural birth defects.	Commun Med (Lond)	2023	https://conductscience.org/library/papers/37460679	PubMed
35,646,932	Zombies Never Die: The Double Life Bub1 Lives in Mitosis.	Front Cell Dev Biol	2022	https://conductscience.org/library/papers/35646932	PubMed
34,925,867	Inhibitors of the Bub1 spindle assembly checkpoint kinase: synthesis of BAY-320 and comparison with 2OH-BNPP1.	R Soc Open Sci	2021	https://conductscience.org/library/papers/34925867	PubMed
34,210,579	Spindle assembly checkpoint activation and silencing at kinetochores.	Semin Cell Dev Biol	2021	https://conductscience.org/library/papers/34210579	PubMed
34,033,659	Yeast Fin1-PP1 dephosphorylates an Ipl1 substrate, Ndc80, to remove Bub1-Bub3 checkpoint proteins from the kinetochore during anaphase.	PLoS Genet	2021	https://conductscience.org/library/papers/34033659	PubMed

1 to 10 of 92

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Genes0

The genes the Gene search release ties to the paper: Swiss-Prot's references first, then PubTator's text mining.

None in this release.

Drugs0

The drugs whose trials, in the Pipelines release, list the paper.

None in this release.

Data1

The data bank entries PubMed's record names. Trial numbers are under Trials.

Data bank	Accession
GENBANK	L32027

Source GENBANK

Data dates

The date of each source this release read.

PubMed: 2026-11-06; PubMed
iCite: 2026-11-05; iCite
PMC's ID file: 2026-11-05; PMC's ID file
NIH RePORTER's grant and paper links: 2026-11-01; NIH RePORTER's grant and paper links
Trials: 2026-11-12
Gene search: 2026-11-11
Pipelines: 2026-09-18

Sources 11

ChEMBL, through Open TargetsCC BY-SA 3.0
ClinicalTrials.govNo license stated
HGNCCC0
iCiteCC BY 4.0
NCBI GenePublic domain (US government)
NIH RePORTER's grant and paper linksPublic domain
Open TargetsCC0 1.0
PMC's ID filePublic domain (US government)
PubMedNLM's terms
PubTator 3Public domain
UniProtCC BY 4.0

Each source's terms

ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
ClinicalTrials.govnone stated
HGNCCC0: https://www.genenames.org/about/license/
iCiteCC BY 4.0
NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
NIH RePORTER's grant and paper linksPublic domain (NIH RePORTER)
Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
PMC's ID fileNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
PubMedNLM's terms
PubTator 3Public domain
UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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