Paper84045
HLA-D region-associated determinants serve as targets for human cell-mediated lysis.
Feighery C and 1 other. J Exp Med, 1979. Cited by 96 papers, by iCite.
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ConductScience Library. HLA-D region-associated determinants serve as targets for human cell-mediated lysis. Papers, record 84045. Release papers-2026-11-12-0.1.0, 12 Nov 2026. https://conductscience.org/library/papers/84045
Paper
PubMed's record of the paper, with iCite's citation figures. No abstract is shown.
Topics9
NLM's MeSH indexing of the paper, its major topics first.
| MeSH term | Major |
|---|---|
| Cytotoxicity, Immunologic | Major topic |
| HLA Antigens | Major topic |
| Lymphocytes | Major topic |
| Major Histocompatibility Complex | Major topic |
| B-Lymphocytes | |
| Epitopes | |
| Humans | |
| Lymphocyte Activation | |
| Monocytes |
Source PubMed
References22
The papers the reference list in PubMed's record names, those in our copy of PubMed, in the list's order.
| Order | PMID | Title | Journal | Year | In Papers | Source |
|---|---|---|---|---|---|---|
| 1 | 1,262,462 | Mixed lymphocyte cultures in rheumatoid arthritis. | J Clin Invest | 1976 | https://conductscience.org/library/papers/1262462 | PubMed |
| 2 | 147,420 | Association of the B-cell alloantigen DRw4 with rheumatoid arthritis. | N Engl J Med | 1978 | https://conductscience.org/library/papers/147420 | PubMed |
| 3 | 179,290 | Epstein-Barr virus and nonhuman primates: natural and experimental infection. | Adv Cancer Res | 1976 | https://conductscience.org/library/papers/179290 | PubMed |
| 4 | 304,270 | Detection of human B lymphocyte alloantigens by complement fixation. | Transplantation | 1977 | https://conductscience.org/library/papers/304270 | PubMed |
| 5 | 4,125,685 | Lymphocyte activation and destruction in vitro in relation to MLC and HL-A. | Transplant Proc | 1973 | https://conductscience.org/library/papers/4125685 | PubMed |
| 6 | 4,130,076 | SD vs. LD antigens as targets for lymphocyte-mediated cytotoxicity: study of a family presenting a recombination event within the MHR. | Transplant Proc | 1973 | https://conductscience.org/library/papers/4130076 | PubMed |
| 7 | 4,137,565 | Cell mediated lympholysis in man. Occurrence of unexpected, HL-A (LA and FOUR) irrelevant lympholysis. | Tissue Antigens | 1974 | https://conductscience.org/library/papers/4137565 | PubMed |
| 8 | 4,267,208 | Cell-mediated lympholysis. Importance of serologically defined H-2 regions. | J Exp Med | 1973 | https://conductscience.org/library/papers/4267208 | PubMed |
| 9 | 4,277,395 | Cell-mediated cell lysis in vitro: genetic control of killer cell production and target specificities in the mouse. | Eur J Immunol | 1974 | https://conductscience.org/library/papers/4277395 | PubMed |
| 10 | 5,155,939 | Cell mediated lympholysis in man after sensitization of effector lymphocytes through mixed leukocyte cultures. | G Batteriol Virol Immunol Ann Osp Maria Vittor Torino | 1971 | https://conductscience.org/library/papers/5155939 | PubMed |
| 11 | 52,680 | Peritoneal macrophages as target cells for measuring virus-specific T cell mediated cytotoxicity in vitro. | J Immunol Methods | 1975 | https://conductscience.org/library/papers/52680 | PubMed |
| 12 | 53,262 | Recognitive specificity of human cytotoxic T lymphocytes. I. Antigen-specific inhibition of human cell-mediated lympholysis. | J Exp Med | 1975 | https://conductscience.org/library/papers/53262 | PubMed |
| 13 | 53,265 | Induction of cytotoxic T lymphocytes against I-region-coded determinants: in vitro evidence for a third histocompatibility locus in the mouse. | J Exp Med | 1975 | https://conductscience.org/library/papers/53265 | PubMed |
| 14 | 53,906 | Cell mediated lympholysis in man. The HL-A third locus antigen, AJ (W20) as sensitizing and/or target determinant. | Tissue Antigens | 1975 | https://conductscience.org/library/papers/53906 | PubMed |
| 15 | 5,417,055 | Mixed lymphocyte cultures produce effector cells: model in vitro for allograft rejection. | Science | 1970 | https://conductscience.org/library/papers/5417055 | PubMed |
| 16 | 59,979 | Tissue distribution of Ia antigens and their expression on lymphocyte subpopulations. | Transplant Rev | 1976 | https://conductscience.org/library/papers/59979 | PubMed |
| 17 | 62,806 | The genetics of cell-mediated lympholysis. | J Immunol | 1976 | https://conductscience.org/library/papers/62806 | PubMed |
| 18 | 65,023 | HLA restriction of non-HLA--A, --B, --C and --D cell mediated lympholysis (CML). | Tissue Antigens | 1976 | https://conductscience.org/library/papers/65023 | PubMed |
| 19 | 66,285 | Genetics of cell-mediated lympholysis in man. | J Immunol | 1977 | https://conductscience.org/library/papers/66285 | PubMed |
| 20 | 68,575 | MLC-activating HLA-D determinants: identification, tissue distribution, and significance. | Transplant Proc | 1977 | https://conductscience.org/library/papers/68575 | PubMed |
Cited by33
The papers in our copy of PubMed whose reference list names this one, newest first. iCite, which reads more sources, counts 96 citations.
| PMID | Title | Journal | Year | In Papers | Source |
|---|---|---|---|---|---|
| 42,115,776 | A new 'K'ind of T helper cell. | Nat Immunol | 2026 | https://conductscience.org/library/papers/42115776 | PubMed |
| 41,917,236 | Regulatory T cells in axial spondyloarthritis. | Commun Biol | 2026 | https://conductscience.org/library/papers/41917236 | PubMed |
| 41,803,090 | Cytotoxic CD4+ T cells: origin, biological functions, diseases and therapeutic targets. | Signal Transduct Target Ther | 2026 | https://conductscience.org/library/papers/41803090 | PubMed |
| 37,965,314 | Cytotoxic CD4+ T cells in chronic viral infections and cancer. | Front Immunol | 2023 | https://conductscience.org/library/papers/37965314 | PubMed |
| 37,654,482 | Cytotoxic CD4 T cells in the mucosa and in cancer. | Front Immunol | 2023 | https://conductscience.org/library/papers/37654482 | PubMed |
| 37,446,355 | Outline of Salivary Gland Pathogenesis of Sjögren's Syndrome and Current Therapeutic Approaches. | Int J Mol Sci | 2023 | https://conductscience.org/library/papers/37446355 | PubMed |
| 37,095,570 | Combining different CRISPR nucleases for simultaneous knock-in and base editing prevents translocations in multiplex-edited CAR T cells. | Genome Biol | 2023 | https://conductscience.org/library/papers/37095570 | PubMed |
| 29,850,628 | Tag7 (PGLYRP1) Can Induce an Emergence of the CD3+CD4+CD25+CD127+ Cells with Antitumor Activity. | J Immunol Res | 2018 | https://conductscience.org/library/papers/29850628 | PubMed |
| 28,280,496 | CD4 CTL, a Cytotoxic Subset of CD4+ T Cells, Their Differentiation and Function. | Front Immunol | 2017 | https://conductscience.org/library/papers/28280496 | PubMed |
| 26,694,968 | CRTAM determines the CD4+ cytotoxic T lymphocyte lineage. | J Exp Med | 2016 | https://conductscience.org/library/papers/26694968 | PubMed |
| 26,388,872 | MHC Class II-Restricted Epitopes Containing an Oxidoreductase Activity Prompt CD4(+) T Cells with Apoptosis-Inducing Properties. | Front Immunol | 2015 | https://conductscience.org/library/papers/26388872 | PubMed |
| 23,947,399 | Substantial increase in the frequency of circulating CD4+NKG2D+ T cells in patients with cervical intraepithelial neoplasia grade 1. | J Biomed Sci | 2013 | https://conductscience.org/library/papers/23947399 | PubMed |
| 23,533,029 | Expanding roles for CD4 T cells and their subpopulations in tumor immunity and therapy. | Front Oncol | 2013 | https://conductscience.org/library/papers/23533029 | PubMed |
| 22,174,559 | Cytotoxic CD4 T cells in antiviral immunity. | J Biomed Biotechnol | 2011 | https://conductscience.org/library/papers/22174559 | PubMed |
| 21,105,780 | Cytolytic CD4(+) T cells in viral immunity. | Expert Rev Vaccines | 2010 | https://conductscience.org/library/papers/21105780 | PubMed |
| 6,980,419 | Long-term human cytolytic T-cell lines allospecific for HLA-DR6 antigen are OKT4+. | Proc Natl Acad Sci U S A | 1982 | https://conductscience.org/library/papers/6980419 | PubMed |
| 6,968,913 | Development and characterization of allospecific long-term human cytolytic T-cell lines. | Proc Natl Acad Sci U S A | 1980 | https://conductscience.org/library/papers/6968913 | PubMed |
| 6,967,946 | Evidence for a new segregant series of B cell antigens that are encoded in the HLA-D region and that stimulate secondary allogenic proliferative and cytotoxic responses. | J Exp Med | 1980 | https://conductscience.org/library/papers/6967946 | PubMed |
| 6,967,856 | Cell-mediated cytotoxicity against HLA-D-region products expressed in monocytes and B lymphocytes. II. HLA-A- or B-antigen compatibility is not required for HLA-D-region directed cytotoxicity. | Immunogenetics | 1980 | https://conductscience.org/library/papers/6967856 | PubMed |
| 6,941,810 | Iridocyclitis in black Americans: association with HLA B8 suggests an autoimmune aetiology. | Br J Ophthalmol | 1981 | https://conductscience.org/library/papers/6941810 | PubMed |
Genes2
The genes the Gene search release ties to the paper: Swiss-Prot's references first, then PubTator's text mining.
| Gene | NCBI Gene ID | Linked by | In Genes | Source |
|---|---|---|---|---|
| HLA-A | 3,105 | PubTator's text mining | https://conductscience.org/library/genes/3105 | NCBI Gene |
| HLA-B | 3,106 | PubTator's text mining | https://conductscience.org/library/genes/3106 | NCBI Gene |
Data dates
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- Trials
- 2026-11-12
- Gene search
- 2026-11-11
- Pipelines
- 2026-09-18
None in this release
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- Trials
- Comments and corrections
- Drugs
- Data
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- ClinicalTrials.govNo license stated
- HGNCCC0
- iCiteCC BY 4.0
- NCBI GenePublic domain (US government)
- NIH RePORTER's grant and paper linksPublic domain
- Open TargetsCC0 1.0
- PMC's ID filePublic domain (US government)
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
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- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- HGNCCC0: https://www.genenames.org/about/license/
- iCiteCC BY 4.0
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH RePORTER's grant and paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PMC's ID fileNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
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