Paper · 9075798

Potential mechanisms by which certain foods promote or inhibit the development of spontaneous diabetes in BB rats: dose, timing, early effect on islet area, and switch in infiltrate from Th1 to Th2 cells.

Scott FW and 6 others. Diabetes, 1997. Cited by 80 papers, by iCite.

11 sourcespapers-2026-11-12-0.1.0

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ConductScience Library. Potential mechanisms by which certain foods promote or inhibit the development of spontaneous diabetes in BB rats: dose, timing, early effect on islet area, and switch in infiltrate from Th1 to Th2 cells. Papers, record 9075798. Release papers-2026-11-12-0.1.0, 12 Nov 2026. https://conductscience.org/library/papers/9075798

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Paper

PubMed's record of the paper, with iCite's citation figures. No abstract is shown.

Title: Potential mechanisms by which certain foods promote or inhibit the development of spontaneous diabetes in BB rats: dose, timing, early effect on islet area, and switch in infiltrate from Th1 to Th2 cells.; PubMed
Journal: Diabetes; PubMed
Year: 1997; PubMed
Publication types: Journal Article, Research Support, Non-U.S. Gov't; PubMed
PubMed: https://pubmed.ncbi.nlm.nih.gov/9075798/; PubMed
DOI: https://doi.org/10.2337/diab.46.4.589; PubMed
The journal: https://conductscience.org/library/journal-index/0372763; PubMed
Citations, by iCite: 80; iCite
Relative citation ratio, by iCite: 2; iCite
Revised in PubMed: 2019-05-15; PubMed

Authors7

The authors in the order PubMed's record lists them, with the ORCID iDs it states.

Order	Author	Forename
1	Scott FW	F W
2	Cloutier HE	H E
3	Kleemann R	R
4	Wöerz-Pagenstert U	U
5	Rowsell P	P
6	Modler HW	H W
7	Kolb H	H

Source PubMed

Topics17

NLM's MeSH indexing of the paper, its major topics first.

MeSH term	Major
Cytokines	Major topic
Diabetes Mellitus, Type 1	Major topic
Diet	Major topic
Pancreas	Major topic
T-Lymphocytes, Helper-Inducer	Major topic
Age Factors
Animals
Disease Models, Animal
Dose-Response Relationship, Drug
Interferon-gamma
Interleukin-10
Rats
Rats, Inbred BB
Th1 Cells
Th2 Cells
Time Factors
Transforming Growth Factor beta

Source PubMed

Grants0

Each grant PubMed's record writes, matched to the NIH project NIH's grant and paper links name for this paper, and each of those links the record does not write.

None in this release.

Trials0

The trials whose ClinicalTrials.gov record lists the paper, and the trial numbers the paper's PubMed record names.

None in this release.

Comments and corrections0

PubMed's comments and corrections, NLM's own indexing: retractions first, then expressions of concern, errata and updates, and comments last.

None in this release.

References0

The papers the reference list in PubMed's record names, those in our copy of PubMed, in the list's order.

None in this release.

Cited by19

The papers in our copy of PubMed whose reference list names this one, newest first. iCite, which reads more sources, counts 80 citations.

PMID	Title	Journal	Year	In Papers	Source
41,536,244	Diet, gut microbiome, and type 1 diabetes: from risk to translational opportunity.	Gut Microbes	2026	https://conductscience.org/library/papers/41536244	PubMed
33,803,255	Dysbiosis in the Development of Type I Diabetes and Associated Complications: From Mechanisms to Targeted Gut Microbes Manipulation Therapies.	Int J Mol Sci	2021	https://conductscience.org/library/papers/33803255	PubMed
32,174,888	The Role of Gut Microbiota and Environmental Factors in Type 1 Diabetes Pathogenesis.	Front Endocrinol (Lausanne)	2020	https://conductscience.org/library/papers/32174888	PubMed
29,293,587	Modulation of the diet and gastrointestinal microbiota normalizes systemic inflammation and β-cell chemokine expression associated with autoimmune diabetes susceptibility.	PLoS One	2018	https://conductscience.org/library/papers/29293587	PubMed
24,871,322	Dietary gluten and the development of type 1 diabetes.	Diabetologia	2014	https://conductscience.org/library/papers/24871322	PubMed
23,349,499	Promotion of autoimmune diabetes by cereal diet in the presence or absence of microbes associated with gut immune activation, regulatory imbalance, and altered cathelicidin antimicrobial Peptide.	Diabetes	2013	https://conductscience.org/library/papers/23349499	PubMed
22,913,724	Dietary gluten alters the balance of pro-inflammatory and anti-inflammatory cytokines in T cells of BALB/c mice.	Immunology	2013	https://conductscience.org/library/papers/22913724	PubMed
22,109,896	Leaky gut and autoimmune diseases.	Clin Rev Allergy Immunol	2012	https://conductscience.org/library/papers/22109896	PubMed
19,538,307	Tight junctions, intestinal permeability, and autoimmunity: celiac disease and type 1 diabetes paradigms.	Ann N Y Acad Sci	2009	https://conductscience.org/library/papers/19538307	PubMed
17,682,002	Mucosal T-cell immunoregulation varies in early and late inflammatory bowel disease.	Gut	2007	https://conductscience.org/library/papers/17682002	PubMed

1 to 10 of 19

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Genes0

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None in this release.

Drugs0

The drugs whose trials, in the Pipelines release, list the paper.

None in this release.

Data0

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None in this release.

Data dates

The date of each source this release read.

PubMed: 2026-11-06; PubMed
iCite: 2026-11-05; iCite
PMC's ID file: 2026-11-05; PMC's ID file
NIH RePORTER's grant and paper links: 2026-11-01; NIH RePORTER's grant and paper links
Trials: 2026-11-12
Gene search: 2026-11-11
Pipelines: 2026-09-18

Sources 11

ChEMBL, through Open TargetsCC BY-SA 3.0
ClinicalTrials.govNo license stated
HGNCCC0
iCiteCC BY 4.0
NCBI GenePublic domain (US government)
NIH RePORTER's grant and paper linksPublic domain
Open TargetsCC0 1.0
PMC's ID filePublic domain (US government)
PubMedNLM's terms
PubTator 3Public domain
UniProtCC BY 4.0

Each source's terms

ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
ClinicalTrials.govnone stated
HGNCCC0: https://www.genenames.org/about/license/
iCiteCC BY 4.0
NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
NIH RePORTER's grant and paper linksPublic domain (NIH RePORTER)
Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
PMC's ID fileNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
PubMedNLM's terms
PubTator 3Public domain
UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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