Trial · NCT03449251
Registered outcomes58
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
21 to 40 of 58
Download this page as JSON| List | Outcome | Time frame | Description |
|---|---|---|---|
| Primary | Sub-Study 3a: Change in forearm blood flow parameters in healthy participants after incremental infusions of intra-arterial relaxin in the presence of apelin (Percentage Change) | Visit 2 to visit 3, over a period of up to 10 weeks | Percentage change in the infused arm, In % |
| Primary | Sub-Study 3b: Change in forearm blood flow parameters in healthy participants after incremental infusions of intra-arterial apelin in the presence of relaxin (Ratio) | Visit 2 to visit 3, over a period of up to 10 weeks | Ratio, expressed as a number (no units as this is a ratio) |
| Primary | Sub-Study 3b: Change in forearm blood flow parameters in healthy participants after incremental infusions of intra-arterial apelin in the presence of relaxin (Absolute Flow) | Visit 2 to visit 3, over a period of up to 10 weeks | Absolute flow in the infused arm, in mg/dL/min |
| Primary | Sub-Study 3b: Change in forearm blood flow parameters in healthy participants after incremental infusions of intra-arterial apelin in the presence of relaxin (Percentage Change) | Visit 2 to visit 3, over a period of up to 10 weeks | Percentage change in the infused arm, In % |
| Primary | Sub-study 4: Changes in markers of glucose homeostasis healthy participants, participants with increased weight and participants with type 2 diabetes mellitus after infusion of relaxin with and without apelin (Glucose) | Visit 2 to Visit 4, over a period of up to 8 weeks | Glucose, in each of the groups, in mmol/L |
| Primary | Sub-study 4: Changes in markers of glucose homeostasis healthy participants, participants with increased weight and participants with type 2 diabetes mellitus after infusion of relaxin with and without apelin (C-peptide) | Visit 2 to Visit 4, over a period of up to 8 weeks | C-peptide, in each of the groups, in pmol/L |
| Primary | Sub-study 4: Changes in markers of glucose homeostasis healthy participants, participants with increased weight and participants with type 2 diabetes mellitus after infusion of relaxin with and without apelin (Glucagon) | Visit 2 to Visit 4, over a period of up to 8 weeks | glucagon, in each of the groups,in pg/ml |
| Primary | Sub-study 4: Changes in markers of glucose homeostasis healthy participants, participants with increased weight and participants with type 2 diabetes mellitus after infusion of relaxin with and without apelin (Insulin) | Visit 2 to Visit 4, over a period of up to 8 weeks | Insulin, in each of the groups, in pmol/L |
| Primary | Sub-study 4: Changes in markers of glucose homeostasis healthy participants, participants with increased weight and participants with type 2 diabetes mellitus after infusion of relaxin with and without apelin (TNF-alpha) | Visit 2 to Visit 4, over a period of up to 8 weeks | TNF-alpha, in each of the groups, in pg/ml |
| Primary | Sub-study 5: Change in hand vein diameter after relaxin infusion in healthy participants | Visit 2 | Hand vein Demeter is measured using Aellig dorsal hand vein technique |
| Secondary | Sub-study 1a: Changes in parameters of cardiovascular haemodynamics in healthy participants after infusion of apelin (Echocardiography) | Visit 2 to visit 4, over a period of up to 8 weeks | Cardiac output measured by Echocardiography, in L/min |
| Secondary | Sub-study 1a: Changes in parameters of cardiovascular haemodynamics in healthy participants after infusion of apelin (Innocor) | Visit 2 to visit 4, over a period of up to 8 weeks | Cardiac output measured by Innocor, in L/min |
| Secondary | Sub-study 1a: Changes in parameters of cardiovascular haemodynamics in healthy participants after infusion of apelin (Bioimpedance) | Visit 2 to visit 4, over a period of up to 8 weeks | Cardiac output measured by bioimpedance, in L/min |
| Secondary | Sub-study 1b: Changes in parameters of cardiovascular haemodynamics in obese/overweight and T2DM participants after infusion of apelin (Echocardiography) | VIsit 2 to visit 4, over a period of up to 8 weeks | Cardiac output measured by Echocardiography, in L/min |
| Secondary | Sub-study 1b: Changes in parameters of cardiovascular haemodynamics in obese/overweight and T2DM participants after infusion of apelin (Innocor) | Visit 2 to visit 4, over a period of up to 8 weeks | Cardiac output measured by Innocor, in L/min |
| Secondary | Sub-study 1b: Changes in parameters of cardiovascular haemodynamics in obese/overweight and T2DM participants after infusion of apelin (Bioimpedance) | Visit 2 to visit 4, over a period of up to 8 weeks | Cardiac output measured by bioimpedance, in L/min |
| Secondary | Sub-study 1b: Changes in parameters of cardiovascular haemodynamics in obese/overweight and T2DM participants after infusion of apelin,after a mixed meal challenge (Echocardiography) | Visit 2 to visit 4, over a period of up to 8 weeks | Cardiac output measured by Echocardiography, in L/min |
| Secondary | Sub-study 1b: Changes in parameters of cardiovascular haemodynamics in obese/overweight and T2DM participants after infusion of apelin, after a mixed meal challenge (Innocor) | Visit 2 to visit 4, over a period of up to 8 weeks | Cardiac output measured by Innocor, in L/min |
| Secondary | Sub-study 1b: Changes in parameters of cardiovascular haemodynamics in obese/overweight and T2DM participants after infusion of apelin,after a mixed meal challenge (Bioimpedance) | VIsit 2 to visit 4, over a period of up to 8 weeks | Cardiac output measured by bioimpedance, in L/min |
| Secondary | Sub-study 1b: Changes in markers of glucose homeostasis after infusion of apelin in obese/overweight and T2DM, after a mixed meal challenge (Clugose) | Visit 2 to visit 5, over a period of up to 14 weeks | Glucose, in mmol/L |
Source ClinicalTrials.govtrials-2026-11-12-0.5.0
Sources 3
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
- NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
- NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
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GET https://conductscience.org/api/trials/v1/NCT03449251/registered?page=2