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Trial · NCT03449251

Registered outcomes58

Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.

ListOutcomeTime frameDescription
SecondarySub-study 1b: Changes in markers of glucose homeostasis after infusion of apelin in obese/overweight and T2DM, after a mixed meal challenge (C-peptide)Visit 2 to visit 5, over a period of up to 14 weeksC-peptide, in pmol/L
SecondarySub-study 1b: Changes in markers of glucose homeostasis after infusion of apelin in obese/overweight and T2DM, after a mixed meal challenge (Glucagon)Visit 2 to visit 5, over a period of up to 14 weeksGlucagon, in pg/ml
SecondarySub-study 1b: Changes in markers of glucose homeostasis after infusion of apelin in obese/overweight and T2DM, after a mixed meal challenge (Insulin)Visit 2 to visit 5, over a period of up to 14 weeksInsulin, in pmol/L
SecondarySub-study 1b: Changes in markers of glucose homeostasis after infusion of apelin in obese/overweight and T2DM, after a mixed meal challenge (TNF alpha)Visit 2 to visit 5, over a period of up to 14 weeksTNF alpha, in pg/ml
SecondarySub-study 2b: Change in forearm blood flow parameters after infusion of verapamil in the presence of L-NMMA or saline (Ratio)Visit 2 to visit 3, over a period of up to 10 weeksRatio,expressed as a number (no units as this is a ratio)
SecondarySub-study 2b: Change in forearm blood flow parameters after infusion of verapamil in the presence of L-NMMA or saline (Absolute Flow)Visit 2 to visit 3, over a period of up to 10 weeksAbsolute flow in the infused arm, in mg/dL/min
SecondarySub-study 2b: Change in forearm blood flow parameters after infusion of verapamil in the presence of L-NMMA or saline (Percentage Change)Visit 2 to visit 3, over a period of up to 10 weeksPercentage change in the infused arm, In %
SecondarySub-study 4: Change in cardiovascular haemodynamics after infusion of relaxin (Echocardiography)Visit 2 to visit 4, over a period of up to 8 weeksCardiac output measured by Echocardiography, in L/min
SecondarySub-study 4: Change in cardiovascular haemodynamics after infusion of relaxin (Bioimpedance)Visit 2 to visit 4, over a period of up to 8 weeksCardiac output measured by bioimpedance, in L/min
SecondarySub-study 4: Change in cardiovascular haemodynamics after infusion of relaxin (Innocor)Visit 2 to visit 4, over a period of up to 8 weeksCardiac output measured by Innocor, in L/min
SecondarySub-study 4: Change in cardiovascular haemodynamics after combined infusion of relaxin and apelin (Echocardiography)Visit 2 to visit 4, over a period of up to 8 weeksCardiac output measured by Echocardiography, in L/min
SecondarySub-study 4: Change in cardiovascular haemodynamics after combined infusion of relaxin and apelin (Bioimpedance)Visit 2 to visit 4, over a period of up to 8 weeksCardiac output measured by bioimpedance, in L/min
SecondarySub-study 4: Change in cardiovascular haemodynamics after combined infusion of relaxin and apelin (Innocor)Visit 2 to visit 4, over a period of up to 8 weeksCardiac output measured by Innocor, in L/min
SecondarySub-study 4: Change in glucose homeostasis after combined infusion of relaxin and apelin (Glucose)Visit 2 to visit 4, over a period of up to 8 weeksGlucose, in mmol/L
SecondarySubstudy 4: Change in glucose homeostasis after combined infusion of relaxin and apelin (C-peptide)Visit 2 to visit 4, over a period of up to 8 weeksC-peptide, in pmol/L
SecondarySub-study 4: Change in glucose homeostasis after combined infusion of relaxin and apelin (Glucagon)Visit 2 to visit 4, over a period of up to 8 weeksGlucagon, in pg/ml
SecondarySub-study 4: Change in glucose homeostasis after combined infusion of relaxin and apelin (Insulin)Visit 2 to visit 4, over a period of up to 8 weeksInsulin, in pmol/L
SecondarySub-study 4: Change in glucose homeostasis after combined infusion of relaxin and apelin (TNF alpha)Visit 2 to visit 4, over a period of up to 8 weeksTNF alpha, glucose homeostasis

Source ClinicalTrials.govtrials-2026-11-12-0.5.0

Sources 3

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ClinicalTrials.govNo license stated
  • NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ClinicalTrials.govnone stated
  • NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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