Trial · NCT04196777
Audit-and-feedback to Improve Antimicrobial-prescribing Among Urologists
NCT04196777, Not applicable, Completed, Iowa City Veterans Affairs Medical Center; results first posted 2024-09-19
3 sourcestrials-2026-11-12-0.5.0
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ConductScience Library. Audit-and-feedback to Improve Antimicrobial-prescribing Among Urologists. Trials, record NCT04196777. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT04196777
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Trial
As registered on ClinicalTrials.gov, in the graph's capture of the registry.
- Title
- Audit-and-feedback to Improve Antimicrobial-prescribing Among Urologists
- NCT number
- NCT04196777
- Status
- Completed
- Phases
- Not applicable
- Enrollment
- 525 participants, actual
- Lead sponsor
- Iowa City Veterans Affairs Medical Center
- Conditions
- Urologic Diseases, Antibacterial Drug Adverse Reaction
- Interventions
- Audit-and-feedback
- First posted
- 2019-12-12
- Last updated
- 2024-09-19
- Results first posted
- 2024-09-19
Source ClinicalTrials.gov
Registered outcomes7
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
| List | Outcome | Time frame | Description |
|---|---|---|---|
| Primary | Percentage of Cases Who Received Excessive Post-procedural Antimicrobials | Within 1 day of the urologic procedure | Excessive post-procedural antimicrobial use is defined as a prescription for a antimicrobial agent on post-procedural day one. For this specific outcome measure, the numerator will be the number of patients who received an excessive post-procedural antimicrobial, and the denominator will be all patients at the site who underwent a qualifying urologic procedure. |
| Secondary | Excessive Post-procedural Antimicrobial Duration (Mean) | Within 30-days of the urologic procedure | Excessive post-procedural antimicrobial duration is defined as the duration of continuous excessive post-procedural antimicrobial use, as quantified as days of therapy per National Healthcare Safety Network methodology. This outcome will be calculated for each patient who underwent a qualifying procedure and received a post-procedural antimicrobial (primary outcome). |
| Secondary | Percentage of Cases Who Received a Late Antimicrobial Prescription | Within 30-days of the urologic procedure | Late antimicrobial prescription is defined as the prescription of a designated antimicrobial that does not qualify as a post-procedural antimicrobial (see above) by any provider within 7-30 days of the date of the patient's urologic procedure. For this specific outcome measure, the numerator will be the number of patients who received a late antimicrobial, and the denominator will be all patients at the site who underwent a qualifying urologic procedure. |
| Secondary | Percentage of Cases Who Were Re-admitted to the Hospital or Presented to an Emergency Department or an Urgent Care Clinic | Within 30-days of the urologic procedure | Return visits: sought urgent/emergent healthcare for any indication within 30 days of the patient's index urologic procedure. For this specific outcome measure, the numerator will be the number of patients who had a return visit for any reason within 30-days of the urologic procedure, and the denominator will be all patients at the site who underwent a qualifying urologic procedure. |
| Secondary | Percentage of Cases Who Died (Mortality) | Within 30-days of the urologic procedure | Mortality: all-cause death within 30-days of the patient's index urologic procedure. For this specific outcome measure, the numerator will be the number of patients who died for any reason within 30-days of the urologic procedure, and the denominator will be all patients at the site who underwent a qualifying urologic procedure. |
| Secondary | Percentage of Cases Who Underwent Clostridioides Difficile Testing | Within 30-days of the urologic procedure | Clostridioides difficile testing is defined as any laboratory test ordered for C. difficile within 30-days of the patient's urologic procedure. For this specific outcome measure, the numerator will be the number of patients who underwent C. difficile testing within 30-days of the procedure, and the denominator will be all patients at the site who underwent a qualifying urologic procedure. |
| Secondary | Percentage of Cases Who Acquired Clostridioides Difficile Infection | Within 30-days of the urologic procedure | Clostridioides difficile infection (CDI) is defined as a positive laboratory test for C.difficile within 30-days of the patient's urologic procedure. For this specific outcome measure, the numerator will be the number of patients who had a positive test for C. difficile within 30-days of the procedure, and the denominator will be all patients at the site who underwent a qualifying urologic procedure. |
Source ClinicalTrials.gov
Outcomes7
Each outcome the trial posted results for, in ClinicalTrials.gov's words.
| Type | Outcome | Time frame | Population | Units | Measured as |
|---|---|---|---|---|---|
| PRIMARY | Percentage of Cases Who Received Excessive Post-procedural Antimicrobials | Within 1 day of the urologic procedure | Participants | COUNT_OF_PARTICIPANTS | |
| SECONDARY | Excessive Post-procedural Antimicrobial Duration (Mean) | Within 30-days of the urologic procedure | Days of antimicrobial therapy | MEAN | |
| SECONDARY | Percentage of Cases Who Received a Late Antimicrobial Prescription | Within 30-days of the urologic procedure | Participants | COUNT_OF_PARTICIPANTS | |
| SECONDARY | Percentage of Cases Who Were Re-admitted to the Hospital or Presented to an Emergency Department or an Urgent Care Clinic | Within 30-days of the urologic procedure | Participants | COUNT_OF_PARTICIPANTS | |
| SECONDARY | Percentage of Cases Who Died (Mortality) | Within 30-days of the urologic procedure | Participants | COUNT_OF_PARTICIPANTS | |
| SECONDARY | Percentage of Cases Who Underwent Clostridioides Difficile Testing | Within 30-days of the urologic procedure | Participants | COUNT_OF_PARTICIPANTS | |
| SECONDARY | Percentage of Cases Who Acquired Clostridioides Difficile Infection | Within 30-days of the urologic procedure | Participants | COUNT_OF_PARTICIPANTS |
Source ClinicalTrials.gov
Results by group14
Each measurement the trial posted, group by group, in the words and numbers it posted.
| Outcome | Group | Category | Value | Spread | Units |
|---|---|---|---|---|---|
| Percentage of Cases Who Received Excessive Post-procedural Antimicrobials | Intervention | 216 | Participants | ||
| Percentage of Cases Who Received Excessive Post-procedural Antimicrobials | Baseline Period | 644 | Participants | ||
| Excessive Post-procedural Antimicrobial Duration (Mean) | Intervention | 4.1 | Standard Deviation 6.4 | Days of antimicrobial therapy | |
| Excessive Post-procedural Antimicrobial Duration (Mean) | Baseline | 5.3 | Standard Deviation 6.4 | Days of antimicrobial therapy | |
| Percentage of Cases Who Received a Late Antimicrobial Prescription | Intervention | 83 | Participants | ||
| Percentage of Cases Who Received a Late Antimicrobial Prescription | Baseline Period | 169 | Participants | ||
| Percentage of Cases Who Were Re-admitted to the Hospital or Presented to an Emergency Department or an Urgent Care Clinic | Intervention | 113 | Participants | ||
| Percentage of Cases Who Were Re-admitted to the Hospital or Presented to an Emergency Department or an Urgent Care Clinic | Baseline Period | 186 | Participants | ||
| Percentage of Cases Who Died (Mortality) | Intervention | 4 | Participants | ||
| Percentage of Cases Who Died (Mortality) | Baseline Period | 4 | Participants |
1 to 10 of 14Source ClinicalTrials.gov
See all 14 results by groupParticipant flow3
How many started, completed or left each group, period by period.
| Period | Milestone | Group | Participants | Units counted |
|---|---|---|---|---|
| Overall Study | STARTED | Intervention | 525 | |
| Overall Study | COMPLETED | Intervention | 525 | |
| Overall Study | NOT COMPLETED | Intervention | 0 |
Source ClinicalTrials.gov
Adverse events2
Each adverse event the trial posted, group by group: the participants affected out of those at risk.
| Type | Event | Organ system | Group | Affected | At risk | Events |
|---|---|---|---|---|---|---|
| serious | Emergency Department, Urgent Care Clinic, or Hospital Re-admission within 30 days of the procedure | Surgical and medical procedures | Intervention | 113 | 525 | 113 |
| serious | Emergency Department, Urgent Care Clinic, or Hospital Re-admission within 30 days of the procedure | Surgical and medical procedures | Baseline | 186 | 1,272 | 186 |
Source ClinicalTrials.gov
Adverse event totals6
The totals the trial posted for each group.
| Total | Group | Affected | At risk |
|---|---|---|---|
| Total, all-cause mortality | Intervention | 4 | 525 |
| Total, all-cause mortality | Baseline | 4 | 1,272 |
| Total, other adverse events | Intervention | 0 | 525 |
| Total, other adverse events | Baseline | 0 | 1,272 |
| Total, serious adverse events | Intervention | 113 | 525 |
| Total, serious adverse events | Baseline | 186 | 1,272 |
Source ClinicalTrials.gov
Papers1
The papers the trial lists on ClinicalTrials.gov.
| PMID | Listed as |
|---|---|
| 39506499 | DERIVED |
Source PubMed
Grants0
The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.
None in this release.
Trial comparisons8
Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.
| Comparison | Source |
|---|---|
| Intervention vs Baseline Period: Percentage of Cases Who Received Excessive Post-procedural Antimicrobials | Trial comparisons |
| Intervention vs Baseline Period: Percentage of Cases Who Received a Late Antimicrobial Prescription | Trial comparisons |
| Intervention vs Baseline Period: Percentage of Cases Who Underwent Clostridioides Difficile Testing | Trial comparisons |
| Intervention vs Baseline Period: Percentage of Cases Who Acquired Clostridioides Difficile Infection | Trial comparisons |
| Intervention vs Baseline Period: Percentage of Cases Who Died (Mortality) | Trial comparisons |
| Intervention vs Baseline: deaths from any cause | Trial comparisons |
| Intervention vs Baseline Period: Percentage of Cases Who Were Re-admitted to the Hospital or Presented to an Emergency Department or an Urgent Care Clinic | Trial comparisons |
| Intervention vs Baseline: serious adverse events | Trial comparisons |
Tests0
The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.
None in this release.
Data dates
The day each source was copied for this release.
Sources 3
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
- NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
- NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this trial from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/trials/v1/NCT04196777
GET https://conductscience.org/api/trials/v1/NCT04196777/registered