Trial · NCT05714644
Community Collaboration to Advance Racial/Ethnic Equity in CRC Screening
NCT05714644, Not applicable, Completed, Massachusetts General Hospital; results first posted 2025-12-26
3 sourcestrials-2026-11-12-0.4.0
Cite this record
ConductScience Library. Community Collaboration to Advance Racial/Ethnic Equity in CRC Screening. Trials, record NCT05714644. Release trials-2026-11-12-0.4.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT05714644
On this page
Trial
As registered on ClinicalTrials.gov, in the graph's capture of the registry.
- Title
- Community Collaboration to Advance Racial/Ethnic Equity in CRC Screening
- NCT number
- NCT05714644
- Status
- Completed
- Phases
- Not applicable
- Enrollment
- 5,127 participants, actual
- Lead sponsor
- Massachusetts General Hospital
- Conditions
- Colorectal Cancer
- Interventions
- FIT kit Screening Test, Cologuard Screening Test
- First posted
- 2023-02-06
- Last updated
- 2025-12-26
- Results first posted
- 2025-12-26
- Limitations and caveats
Boston and LA used different FIT kit brands. No access to patient-level data about outreach attempts or contacts from the Exact Science patient support program because this information is proprietary.~Unable to comment on cost-effectiveness. Unable to randomize the South Dakota site because unable to identify another CHC in the region to participate.
Source ClinicalTrials.gov
Registered outcomes3
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
| List | Outcome | Time frame | Description |
|---|---|---|---|
| Primary | CRC Screening Completion Rates | 3 months | completion rate of the stool-based screening test (FIT or Cologuard) |
| Secondary | CRC Screening Completion Rates | 6 months | completion rate of the stool-based screening test (Cologuard or FIT) |
| Secondary | Diagnostic Colonoscopy Completion Rates | 6 months | completion rate of diagnostic colonoscopy after an abnormal stool test result (overall and by arm) |
Source ClinicalTrials.gov
Outcomes3
Each outcome the trial posted results for, in ClinicalTrials.gov's words.
| Type | Outcome | Time frame | Population | Units | Measured as |
|---|---|---|---|---|---|
| PRIMARY | CRC Screening Completion Rates | 3 months | Participants | COUNT_OF_PARTICIPANTS | |
| SECONDARY | CRC Screening Completion Rates | 6 months | Participants | COUNT_OF_PARTICIPANTS | |
| SECONDARY | Diagnostic Colonoscopy Completion Rates | 6 months | The number is for participants who returned an abnormal stool test within 180 days. | Participants | COUNT_OF_PARTICIPANTS |
Source ClinicalTrials.gov
Results by group6
Each measurement the trial posted, group by group, in the words and numbers it posted.
| Outcome | Group | Category | Value | Spread | Units |
|---|---|---|---|---|---|
| CRC Screening Completion Rates | Mailed FIT Kit | 550 | Participants | ||
| CRC Screening Completion Rates | Cologuard | 751 | Participants | ||
| CRC Screening Completion Rates | Mailed FIT Kit | 649 | Participants | ||
| CRC Screening Completion Rates | Cologuard | 854 | Participants | ||
| Diagnostic Colonoscopy Completion Rates | Mailed FIT Kit | 13 | Participants | ||
| Diagnostic Colonoscopy Completion Rates | Cologuard | 23 | Participants |
Source ClinicalTrials.gov
Participant flow6
How many started, completed or left each group, period by period.
| Period | Milestone | Group | Participants | Units counted |
|---|---|---|---|---|
| Overall Study | STARTED | Mailed FIT Kit | 2,435 | 4 |
| Overall Study | STARTED | Cologuard | 2,692 | 4 |
| Overall Study | COMPLETED | Mailed FIT Kit | 2,435 | 4 |
| Overall Study | COMPLETED | Cologuard | 2,692 | 4 |
| Overall Study | NOT COMPLETED | Mailed FIT Kit | 0 | 0 |
| Overall Study | NOT COMPLETED | Cologuard | 0 | 0 |
Source ClinicalTrials.gov
Adverse events0
Each adverse event the trial posted, group by group: the participants affected out of those at risk.
None in this release.
Adverse event totals6
The totals the trial posted for each group.
| Total | Group | Affected | At risk |
|---|---|---|---|
| Total, all-cause mortality | Mailed FIT Kit | 0 | 2,435 |
| Total, all-cause mortality | Cologuard | 0 | 2,692 |
| Total, other adverse events | Mailed FIT Kit | 0 | 2,435 |
| Total, other adverse events | Cologuard | 0 | 2,692 |
| Total, serious adverse events | Mailed FIT Kit | 0 | 2,435 |
| Total, serious adverse events | Cologuard | 0 | 2,692 |
Source ClinicalTrials.gov
Papers2
The papers the trial lists on ClinicalTrials.gov.
Grants0
The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.
None in this release.
Trial comparisons5
Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.
| Comparison | Source |
|---|---|
| Mailed FIT Kit vs Cologuard: Diagnostic Colonoscopy Completion Rates | Trial comparisons |
| Mailed FIT Kit vs Cologuard: CRC Screening Completion Rates | Trial comparisons |
| Mailed FIT Kit vs Cologuard: CRC Screening Completion Rates | Trial comparisons |
| Mailed FIT Kit vs Cologuard: deaths from any cause | Trial comparisons |
| Mailed FIT Kit vs Cologuard: serious adverse events | Trial comparisons |
Tests0
The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.
None in this release.
Data dates
The day each source was copied for this release.
Sources 3
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
- NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
- NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this trial from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/trials/v1/NCT05714644
GET https://conductscience.org/api/trials/v1/NCT05714644/registered